LOCUS BC030981 2269 bp mRNA linear HUM 16-DEC-2006
DEFINITION Homo sapiens high-mobility group box 1, mRNA (cDNA clone MGC:32637
IMAGE:4041682), complete cds.
ACCESSION BC030981
VERSION BC030981.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2269)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2269)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 41 Row: a Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56806672.
FEATURES Location/Qualifiers
source 1..2269
/db_xref="H-InvDB:HIT000041185"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:32637 IMAGE:4041682"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_61"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..2269
/gene="HMGB1"
/gene_synonym="HMG3"
/gene_synonym="SBP-1"
/db_xref="GeneID:3146"
/db_xref="HGNC:HGNC:4983"
/db_xref="MIM:163905"
CDS 96..743
/gene="HMGB1"
/gene_synonym="HMG3"
/gene_synonym="SBP-1"
/codon_start=1
/product="high-mobility group box 1"
/protein_id="AAH30981.1"
/db_xref="GeneID:3146"
/db_xref="HGNC:HGNC:4983"
/db_xref="MIM:163905"
/translation="MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKK
CSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAF
FLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIA
AYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE"
BASE COUNT 754 a 367 c 465 g 683 t
ORIGIN
1 cagtacattg agctccatag agacagcgcc ggggcaagtg agagccggac gggcactggg
61 cgactctgtg cctcgctgag gaaaaataac taaacatggg caaaggagat cctaagaagc
121 cgagaggcaa aatgtcatca tatgcatttt ttgtgcaaac ttgtcgggag gagcataaga
181 agaagcaccc agatgcttca gtcaacttct cagagttttc taagaagtgc tcagagaggt
241 ggaagaccat gtctgctaaa gagaaaggaa aatttgaaga tatggcaaaa gcggacaagg
301 cccgttatga aagagaaatg aaaacctata tccctcccaa aggggagaca aaaaagaagt
361 tcaaggatcc caatgcaccc aagaggcctc cttcggcctt cttcctcttc tgctctgagt
421 atcgcccaaa aatcaaagga gaacatcctg gcctgtccat tggtgatgtt gcgaagaaac
481 tgggagagat gtggaataac actgctgcag atgacaagca gccttatgaa aagaaggctg
541 cgaagctgaa ggaaaaatac gaaaaggata ttgctgcata tcgagctaaa ggaaagcctg
601 atgcagcaaa aaagggagtt gtcaaggctg aaaaaagcaa gaaaaagaag gaagaggagg
661 aagatgagga agatgaagag gatgaggagg aggaggaaga tgaagaagat gaagatgaag
721 aagaagatga tgatgatgaa taagttggtt ctagcgcagt tttttttttt tcttgtctat
781 aaagcattta acccccctgt acacaactca ctccttttaa agaaaaaaat tgaaatgtaa
841 ggctgtgtaa gatttgtttt taaactgtac agtgtctttt tttgtatagt taacacacta
901 ccgaatgtgt ctttagatag ccctgtcctg gtggtatttt caatagccac taaccttgcc
961 tggtacagta tgggggttgt aaattggcat ggaaatttaa agcaggttct tgttggtgca
1021 cagcacaaat tagttatata tggggatggt agttttttca tcttcagttg tctctgatgc
1081 agcttatacg aaataattgt tgttctgtta actgaatacc actctgtaat tgcaaaaaaa
1141 aaaaagttgc agctgttttg ttgacattct gaatgcttct aagtaaatac aatttttttt
1201 attagtattg ttgtcctttt cataggtctg aaatttttct tcttgagggg aagctagtct
1261 tttgcttttg cccattttga atcacatgaa ttattacagt gtctatcctt tcatatagtt
1321 agctaataaa aagcttttgt ctacacaccc tgcatatcat aatgggggta aagttaagtt
1381 gagatagttt tcatccataa ctgaacatcc aaaatcttga tcagttaaga aatttcacat
1441 agcccactta catttacaaa ctgaagagta atcaatctac tcaaagcatg ggattattag
1501 aatcaaacat tttgaaagtc tgtccttgaa ggactaatag aaaagtatgt tctaaccttt
1561 acatgaggac tctattcttt aactcccatt accatgtaat ggcagttata ttttgcagtt
1621 cccacattaa agaagacctg agaatgtatc cccaaaagcg tgagcttaaa atacaagact
1681 gccatattaa attttttgtt gacattagtc tcagtgaaga ctatgaaaat gctggctata
1741 gatgtctttt cccatttatc taaatatgga ctgctcagga aacgagactt tcattacaag
1801 tatttttaat taattgggcc agcttttcaa acaaagatgc cacattcaaa atagggtata
1861 ttttcctata ttacggtttg cccctttata aatccaagta gataggaaga aagaagacaa
1921 actttgcatc tcagtatgaa ttattcaatt tatttgaatg atttttcttt acaaaacaaa
1981 ctcattcatt agtcatgttt atctgcttag gagtttaggg aacaatttgg caattttgtg
2041 gttttcgaga ttatcgtttt cttaaagtgc cagtatttta aaatagcgtt cttgtaattt
2101 tacacgcttt tgtgatggag tgctgttttg ttatataatt tagacttgga ttctttccat
2161 ttgcatttgt ttatgtaatt tcaggaggaa tactgaacat ctgagtcctg gatgatacta
2221 ataaactaat aattgcagta aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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