LOCUS BC018543 2498 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens ArfGAP with coiled-coil, ankyrin repeat and PH domains
1, mRNA (cDNA clone MGC:16966 IMAGE:4342840), complete cds.
ACCESSION BC018543
VERSION BC018543.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2498)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2498)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: k Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41281459.
FEATURES Location/Qualifiers
source 1..2498
/db_xref="H-InvDB:HIT000038363"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:16966 IMAGE:4342840"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2498
/gene="ACAP1"
/db_xref="GeneID:9744"
/db_xref="HGNC:HGNC:16467"
/db_xref="MIM:607763"
CDS 182..2404
/gene="ACAP1"
/codon_start=1
/product="ArfGAP with coiled-coil, ankyrin repeat and PH
domains 1"
/protein_id="AAH18543.1"
/db_xref="GeneID:9744"
/db_xref="HGNC:HGNC:16467"
/db_xref="MIM:607763"
/translation="MTVKLDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTG
LLESGRHYLAASRAFVVGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQ
HTLQQQIQTLVKEGLRGFREARRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALR
TARAGYRGRALDYALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRK
ELGAQLHQLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRA
SNAFKTWSRRWFTIQSNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVST
SKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATLGS
GGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL
GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEA
WIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDL
GSLHPGALLFRASGHPPSLPTMADALAHGADVNWVNGGQDNATPLIQATAANSLLACE
FLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAME
TANADIVTLLRLAKMREAEAAQGQAGDETYLDIFRDFSLMASDDPEKLSRRSHDLHTL
"
BASE COUNT 519 a 750 c 770 g 459 t
ORIGIN
1 gagctcctcc taggacaccc ctttcccctt ggggaaagga ttgtgccccc aggcccttcc
61 ccgcggaggt ccctctcctc cttccccctc atctcccctt cctgggacag aaagtgcctc
121 cacctgcatc cccaggggcc cggcctccag ggcccgctgg ccccacagca ggcaagctga
181 gatgacggtc aagctggatt tcgaggagtg tctcaaggac tcaccccgtt tccgagcctc
241 tattgagctg gtggaagccg aagtgtcaga attggagacc cgtctggaaa agctcctgaa
301 actgggcact ggtctcctgg aaagtgggcg ccattacctt gctgccagcc gcgccttcgt
361 tgtcggcatt tgtgacctgg cccgcctggg tccaccagag cccatgatgg cggagtgtct
421 ggaaaaattc accgtgagcc tgaaccacaa gctggacagc catgcggagc ttctagatgc
481 cacccaacac acactgcagc agcagatcca gaccctggtc aaggaaggtc tgcggggttt
541 ccgagaggct cgccgggatt tctggcgggg ggctgagagc ctggaggctg ccctgaccca
601 caacgcagag gttcccaggc gccgggccca ggaggcagaa gaggcaggag ctgctttgag
661 gacggctcga gctgggtacc ggggacgggc actggattat gccctgcaga tcaacgtgat
721 tgaggacaag aggaagtttg acatcatgga gtttgtgctg cgtttggtgg aggcccaggc
781 tacccatttc cagcagggcc atgaggagct gagccggctg tcccagtatc gaaaggagct
841 gggcgcccag ttgcaccagc tggtcttgaa ttcagcacga gagaagaggg acatggagca
901 gagacacgtg ctgctgaaac agaaggagct gggtggggag gagccagaac caagcttaag
961 agaggggcct ggtggcctgg tgatggaagg acatctcttc aaacgggcca gcaacgcatt
1021 taagacctgg agcagacgct ggttcaccat tcagagcaac caactggttt accagaagaa
1081 gtacaaggac cctgtgactg tggtggtgga tgaccttcgt ctctgcacag tgaaactctg
1141 ccctgactca gaaaggcggt tctgctttga ggtggtgtcc accagcaagt cctgcctcct
1201 ccaggctgac tcagagcgcc tcctgcagct gtgggtcagt gctgtgcaga gcagcattgc
1261 ttctgccttc agtcaggctc gccttgatga cagcccccgg ggtccaggcc agggctcagg
1321 acacctggcc ataggctctg ctgccaccct gggctctggt ggaatggcca ggggaaggga
1381 gcctggggga gtcgggcacg tggtggccca ggtccagagt gtggatggca atgcccagtg
1441 ctgcgactgc cgggagccag ccccggagtg ggccagcatc aaccttggtg tcaccctctg
1501 cattcagtgt tccggcatcc acaggagcct tggtgttcac ttctccaaag tccggtctct
1561 gacccttgac tcatgggagc cagaactagt gaagctcatg tgtgagctgg gaaatgtcat
1621 catcaaccag atctatgagg cccgcgtgga ggccatggca gtgaagaaac cagggcccag
1681 ctgctcccgg caggagaagg aggcctggat tcacgctaaa tacgtggaga agaagttcct
1741 gaccaagctg cctgagattc gagggcgaag aggtggccgg gggcgcccaa gggggcagcc
1801 tcctgtgccc ccaaagcctt ccatcaggcc ccggccaggg agcttgagat ccaagccaga
1861 gcccccctct gaggacctgg gaagcctgca ccctggggcc ctactgtttc gagcgtctgg
1921 gcatcctcca tctcttccca ccatggctga tgcccttgcc catggagctg atgtcaactg
1981 ggtcaatggg ggccaagata atgccacacc gctgatccag gccacagctg ctaattctct
2041 tctggcctgt gagtttctcc tccagaacgg ggcgaacgtg aaccaagcgg acagtgcggg
2101 ccggggcccg ctgcaccacg caaccattct tggccacacg gggctcgcct gcctgttcct
2161 gaaacgggga gctgatctgg gggctcgaga ctctgaaggc agggaccctc tgaccatcgc
2221 catggaaaca gccaacgctg acatcgtcac cctgctacga ctggcaaaga tgagggaggc
2281 tgaagcggcc caggggcagg caggagatga gacgtatctt gacatcttcc gcgacttctc
2341 cctcatggcg tcagacgacc cggagaagct gagccgtcgc agtcatgacc tccacacgct
2401 gtgacccgag gcccacgggg cccgcgcctg cctcccttcc ccgccaccgg gccctctgcc
2461 attaaagcct ccgtgcttcg ctcaaaaaaa aaaaaaaa
//