LOCUS BC013361 2776 bp mRNA linear HUM 11-SEP-2007
DEFINITION Homo sapiens vav 1 guanine nucleotide exchange factor, mRNA (cDNA
clone MGC:15356 IMAGE:3842829), complete cds.
ACCESSION BC013361
VERSION BC013361.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2776)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2776)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC013361.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 25 Row: a Column: 16.
FEATURES Location/Qualifiers
source 1..2776
/db_xref="H-InvDB:HIT000036231"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15356 IMAGE:3842829"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2776
/gene="VAV1"
/db_xref="GeneID:7409"
/db_xref="HGNC:HGNC:12657"
/db_xref="MIM:164875"
CDS 86..2458
/gene="VAV1"
/codon_start=1
/product="VAV1 protein"
/protein_id="AAH13361.2"
/db_xref="GeneID:7409"
/db_xref="HGNC:HGNC:12657"
/db_xref="MIM:164875"
/translation="MIVLPLYSRLDKRFLCLKNIRTFLSTCCEKFGLKRSELFEAFDL
FDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDE
DLYDCVENEEAEGDEIYEDLMRSEPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGS
IQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKY
KERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQ
RVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLS
IENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRGDSYDLKDFV
NLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISN
IYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPP
CGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNP
GDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERA
GAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRG
LTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCA
RDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC"
BASE COUNT 737 a 699 c 795 g 545 t
ORIGIN
1 gtggtgcacg cctatagtct cagctactca ggaagttgag gcaggaggat cgcttgagcc
61 caggagtttg atgctgcagt gagctatgat tgtgctacca ctgtactcca gactggacaa
121 aagattcctg tgccttaaga acattagaac cttcctgtcc acctgctgtg agaagttcgg
181 cctcaagcgg agcgagctct tcgaagcctt tgacctcttc gatgtgcagg attttggcaa
241 ggtcatctac accctgtctg ctctgtcctg gaccccgatc gcccagaaca gggggatcat
301 gcccttcccc accgaggagg agagtgtagg tgatgaagac atctacagtg gcctgtccga
361 ccagatcgac gacacggtgg aggaggatga ggacctgtat gactgcgtgg agaatgagga
421 ggcggaaggc gacgagatct atgaggacct catgcgctcg gagcccgtgt ccatgccgcc
481 caagatgaca gagtatgaca agcgctgctg ctgcctgcgg gagatccagc agacggagga
541 gaagtacact gacacgctgg gctccatcca gcagcatttc ttgaagcccc tgcaacggtt
601 cctgaaacct caagacattg agatcatctt tatcaacatt gaggacctgc ttcgtgttca
661 tactcacttc ctaaaggaga tgaaggaagc cctgggcacc cctggcgcag ccaatctcta
721 ccaggtcttc atcaaataca aggagaggtt cctcgtctat ggccgctact gcagccaggt
781 ggagtcagcc agcaaacacc tggaccgtgt ggccgcagcc cgggaggacg tgcagatgaa
841 gctggaggaa tgttctcaga gagccaacaa cgggaggttc accctgcggg acctgctgat
901 ggtgcctatg cagcgagttc tcaaatatca cctccttctc caggagctgg tgaaacacac
961 gcaggaggcg atggagaagg agaacctgcg gctggccctg gatgccatga gggacctggc
1021 tcagtgcgtg aacgaggtca agcgagacaa cgagacactg cgacagatca ccaatttcca
1081 gctgtccatt gagaacctgg accagtctct ggctcactat ggccggccca agatcgacgg
1141 ggaactcaag atcacctcgg tggaacggcg ctccaagatg gacaggtatg ccttcctgct
1201 cgacaaagct ctactcatct gtaagcgcag gggagactcc tatgacctca aggactttgt
1261 aaacctgcac agcttccagg ttcgggatga ctcttcagga gaccgagaca acaagaagtg
1321 gagccacatg ttcctcctga tcgaggacca aggtgcccag ggctatgagc tgttcttcaa
1381 gacaagagaa ttgaagaaga agtggatgga gcagtttgag atggccatct ccaacatcta
1441 tccggagaat gccaccgcca acgggcatga cttccagatg ttctcctttg aggagaccac
1501 atcctgcaag gcctgtcaga tgctgcttag aggtaccttc tatcagggct accgctgcca
1561 tcggtgccgg gcatctgcac acaaggagtg tctggggagg gtccctccat gtggccgaca
1621 tgggcaagat ttcccaggaa ctatgaagaa ggacaaacta catcgcaggg ctcaggacaa
1681 aaagaggaat gagctgggtc tgcccaagat ggaggtgttt caggaatact acgggcttcc
1741 tccaccccct ggagccattg gaccctttct acggctcaac cctggagaca ttgtggagct
1801 cacgaaggct gaggctgaac agaactggtg ggagggcaga aatacatcta ctaatgaaat
1861 tggctggttt ccttgtaaca gggtgaagcc ctatgtccat ggccctcctc aggacctgtc
1921 tgttcatctc tggtacgcag gccccatgga gcgggcaggg gcagagagca tcctggccaa
1981 ccgctcggac gggactttct tggtgcggca gagggtgaag gatgcagcag aatttgccat
2041 cagcattaaa tataacgtcg aggtcaagca cattaaaatc atgacagcag aaggactgta
2101 ccggatcaca gagaaaaagg ctttccgggg gcttacggag ctggtggagt tttaccagca
2161 gaactctcta aaggattgct tcaagtctct ggacaccacc ttgcagttcc ccttcaagga
2221 gcctgaaaag agaaccatca gcaggccagc agtgggaagc acaaagtatt ttggcacagc
2281 caaagcccgc tatgacttct gcgcccgaga ccgatcagag ctgtcgctca aggagggtga
2341 catcatcaag atccttaaca agaagggaca gcaaggctgg tggcgagggg agatctatgg
2401 ccgggttggc tggttccctg ccaactacgt ggaggaagat tattctgaat actgctgagc
2461 cctggtgcct tggcagagag acgagaaact ccaggctctg agcccggcgt gggcaggcag
2521 cggagccagg ggctgtgaca gctcccggcg ggtggagact ttgggatgga ctggaggagg
2581 ccagcgtcca gctggcggtg ctcccgggat gtgccctgac atggttaatt tataacaccc
2641 cgatttcctc ttgggtcccc tcaagcagac ggggctcaag ggggttacat ttaataaaag
2701 gatgaagatg gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaa
//