LOCUS BC009395 1624 bp mRNA linear HUM 08-OCT-2003
DEFINITION Homo sapiens interferon regulatory factor 3, mRNA (cDNA clone
MGC:15293 IMAGE:4135383), complete cds.
ACCESSION BC009395
VERSION BC009395.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1624)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1624)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC009395.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 26 Row: l Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504724.
FEATURES Location/Qualifiers
source 1..1624
/db_xref="H-InvDB:HIT000034334"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15293 IMAGE:4135383"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1624
/gene="IRF3"
/db_xref="GeneID:3661"
/db_xref="MIM:603734"
CDS 181..1539
/gene="IRF3"
/codon_start=1
/product="IRF3 protein"
/protein_id="AAH09395.1"
/db_xref="GeneID:3661"
/db_xref="MIM:603734"
/translation="MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQ
DAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHD
PHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSL
AVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQ
TISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWR
AGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRS
DYLHGRKRTLTTLCPLVLCGGVMAPGPAVDQEARDGQGCAHVPQGLGRNGPGRGCLLP
GEYCGPAHFQQPPTLPHLRPVQGLPAGLGGGHGFPGPWGDLSPRSSWCASNPPVPHHL
NQ"
misc_feature 181..513
/gene="IRF3"
/note="IRF; Region: interferon regulatory factor"
/db_xref="CDD:smart00348"
BASE COUNT 385 a 472 c 486 g 281 t
ORIGIN
1 aaagaatgat aaagttggtt ttatttcaag aagtcgatcg aaaagaaagc cccagcgctc
61 tagagctcag ctgacgggaa agggggtgcg cagcctcgag tttgagagct acccggagcc
121 ccaagacagg ggggggttcc agctgcccgc acgccccgac cttccatcgt aggccggacc
181 atgggaaccc caaagccacg gatcctgccc tggctggtgt cgcagctgga cctggggcaa
241 ctggagggcg tggcctgggt gaacaagagc cgcacgcgct tccgcatccc ttggaagcac
301 ggcctacggc aggatgcaca gcaggaggat ttcggaatct tccaggcctg ggccgaggcc
361 actggtgcat atgttcccgg gagggataag ccagacctgc caacctggaa gaggaatttc
421 cgctctgccc tcaaccgcaa agaagggttg cgtttagcag aggaccggag caaggaccct
481 cacgacccac ataaaatcta cgagtttgtg aactcaggag ttggggactt ttcccagcca
541 gacacctctc cggacaccaa tggtggaggc agtacttctg atacccagga agacattctg
601 gatgagttac tgggtaacat ggtgttggcc ccactcccag atccgggacc cccaagcctg
661 gctgtagccc ctgagccctg ccctcagccc ctgcggagcc ccagcttgga caatcccact
721 cccttcccaa acctggggcc ctctgagaac ccactgaagc ggctgttggt gccgggggaa
781 gagtgggagt tcgaggtgac agccttctac cggggccgcc aagtcttcca gcagaccatc
841 tcctgcccgg agggcctgcg gctggtgggg tccgaagtgg gagacaggac gctgcctgga
901 tggccagtca cactgccaga ccctggcatg tccctgacag acaggggagt gatgagctac
961 gtgaggcatg tgctgagctg cctgggtggg ggactggctc tctggcgggc cgggcagtgg
1021 ctctgggccc agcggctggg gcactgccac acatactggg cagtgagcga ggagctgctc
1081 cccaacagcg ggcatgggcc tgatggcgag gtccccaagg acaaggaagg aggcgtgttt
1141 gacctggggc ccttcattgt aggctcctgg gcccccagat ctgattacct tcacggaagg
1201 aagcggacgc tcaccacgct atgccctctg gttctgtgtg ggggagtcat ggccccagga
1261 ccagccgtgg accaagaggc tcgtgatggt caaggttgtg cccacgtgcc tcagggcctt
1321 ggtagaaatg gcccgggtag ggggtgcctc ctccctggag aatactgtgg acctgcacat
1381 ttccaacagc cacccactct ccctcacctc cgaccagtac aaggcctacc tgcaggactt
1441 ggtggagggc atggatttcc agggccctgg ggagacctga gccctcgctc ctcatggtgt
1501 gcctccaacc cccctgttcc ccaccacctc aaccaataaa ctggttcctg ctatgaaaaa
1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1621 aaaa
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