LOCUS BC008366 1964 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens dopa decarboxylase (aromatic L-amino acid
decarboxylase), mRNA (cDNA clone MGC:4310 IMAGE:2819761), complete
cds.
ACCESSION BC008366
VERSION BC008366.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1964)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1964)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 9 Row: k Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 49472824.
FEATURES Location/Qualifiers
source 1..1964
/db_xref="H-InvDB:HIT000033744"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4310 IMAGE:2819761"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1964
/gene="DDC"
/gene_synonym="AADC"
/db_xref="GeneID:1644"
/db_xref="HGNC:HGNC:2719"
/db_xref="MIM:107930"
CDS 76..1518
/gene="DDC"
/gene_synonym="AADC"
/codon_start=1
/product="dopa decarboxylase (aromatic L-amino acid
decarboxylase)"
/protein_id="AAH08366.1"
/db_xref="GeneID:1644"
/db_xref="HGNC:HGNC:2719"
/db_xref="MIM:107930"
/translation="MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPA
AAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIG
FSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAAR
TKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMR
ASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAG
SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLK
HSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLV
RQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAI
CSRTVESAHVQRAWEHIKELAADVLRAERE"
BASE COUNT 517 a 463 c 506 g 478 t
ORIGIN
1 aattcgggca cgagggagga cagagagcaa gtcactcccg gctgcctttt tcacctctga
61 cagagcccag acaccatgaa cgcaagtgaa ttccgaagga gagggaagga gatggtggat
121 tacgtggcca actacatgga aggcattgag ggacgccagg tctaccctga cgtggagccc
181 gggtacctgc ggccgctgat ccctgccgct gcccctcagg agccagacac gtttgaggac
241 atcatcaacg acgttgagaa gataatcatg cctggggtga cgcactggca cagcccctac
301 ttcttcgcct acttccccac tgccagctcg tacccggcca tgcttgcgga catgctgtgc
361 ggggccattg gctgcatcgg cttctcctgg gcggcaagcc cagcatgcac agagctggag
421 actgtgatga tggactggct cgggaagatg ctggaactac caaaggcatt tttgaatgag
481 aaagctggag aagggggagg agtgatccag ggaagtgcca gtgaagccac cctggtggcc
541 ctgctggccg ctcggaccaa agtgatccat cggctgcagg cagcgtcccc agagctcaca
601 caggccgcta tcatggagaa gctggtggct tactcatccg atcaggcaca ctcctcagtg
661 gaaagagctg ggttaattgg tggagtgaaa ttaaaagcca tcccctcaga tggcaacttc
721 gccatgcgtg cgtctgccct gcaggaagcc ctggagagag acaaagcggc tggcctgatt
781 cctttcttta tggttgccac cctggggacc acaacatgct gctcctttga caatctctta
841 gaagtcggtc ctatctgcaa caaggaagac atatggctgc acgttgatgc agcctacgca
901 ggcagtgcat tcatctgccc tgagttccgg caccttctga atggagtgga gtttgcagat
961 tcattcaact ttaatcccca caaatggcta ttggtgaatt ttgactgttc tgccatgtgg
1021 gtgaaaaaga gaacagactt aacgggagcc tttagactgg accccactta cctgaagcac
1081 agccatcagg attcagggct tatcactgac taccggcatt ggcagatacc actgggcaga
1141 agatttcgct ctttgaaaat gtggtttgta tttaggatgt atggagtcaa aggactgcag
1201 gcttatatcc gcaagcatgt ccagctgtcc catgagtttg agtcactggt gcgccaggat
1261 ccccgctttg aaatctgtgt ggaagtcatt ctggggcttg tctgctttcg gctaaagggt
1321 tccaacaaag tgaatgaagc tcttctgcaa agaataaaca gtgccaaaaa aatccacttg
1381 gttccatgtc acctcaggga caagtttgtc ctgcgctttg ccatctgttc tcgcacggtg
1441 gaatctgccc atgtgcagcg ggcctgggaa cacatcaaag agctggcggc cgacgtgctg
1501 cgagcagaga gggagtagga gtgaagccag ctgcaggaat caaaaattga agagagatat
1561 atctgaaaac tggaataaga agcaaataaa tatcatcctg ccttcatgga actcagctgt
1621 ctgtggcttc ccatgtcttt ctccaaagtt atccagaggg ttgtgatttt gtctgcttag
1681 tatctcatca acaaagaaat attatttgct aattaaaaag ttaatcttca tggccatagc
1741 ttttattcat tagctgtgat ttttgttgat taaaacatta tagattttca tgttcttgca
1801 gtcatcagaa gtggtaggaa agcctcactg atatattttc cagggcaatc aatgttcacg
1861 caacttgaaa ttatatctgt ggtcttcaaa ttgtcttttg tcatgtggct aaatgcctaa
1921 taaacaattc aagtgaaata ctaaaaaaaa aaaaaaaaaa aaaa
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