LOCUS BC008090 1429 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens activating transcription factor 4 (tax-responsive
enhancer element B67), mRNA (cDNA clone MGC:9337 IMAGE:3454473),
complete cds.
ACCESSION BC008090
VERSION BC008090.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1429)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1429)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: a Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33469973.
FEATURES Location/Qualifiers
source 1..1429
/db_xref="H-InvDB:HIT000033643"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9337 IMAGE:3454473"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1429
/gene="ATF4"
/gene_synonym="CREB-2"
/gene_synonym="CREB2"
/gene_synonym="TAXREB67"
/db_xref="GeneID:468"
/db_xref="HGNC:HGNC:786"
/db_xref="MIM:604064"
CDS 265..1320
/gene="ATF4"
/gene_synonym="CREB-2"
/gene_synonym="CREB2"
/gene_synonym="TAXREB67"
/codon_start=1
/product="activating transcription factor 4
(tax-responsive enhancer element B67)"
/protein_id="AAH08090.1"
/db_xref="GeneID:468"
/db_xref="HGNC:HGNC:786"
/db_xref="MIM:604064"
/translation="MTEMSFLSSEVLVGDLMSPFDPSGLGAEESLGLLDDYLEVAKHF
KPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGI
DDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFL
QPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDND
SGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGE
KLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYL
KDLIEEVRKARGKKRVP"
BASE COUNT 383 a 365 c 382 g 299 t
ORIGIN
1 cacagatgta gttttctctg cgcgtgtgcg ttttccctcc tcccccgccc tcagggtcca
61 cggccaccat ggcgtattag gggcagcagt gcctgcggca gcattggcct ttgcagcggc
121 ggcagcagca ccaggctctg cagcggcaac ccccagcggc ttaagccatg gcgcttctca
181 cggcattcag cagcagcgtt gctgtaaccg acaaagacac cttcgaatta agcacattcc
241 tcgattccag caaagcaccg caacatgacc gaaatgagct tcctgagcag cgaggtgttg
301 gtgggggact tgatgtcccc cttcgacccg tcgggtttgg gggctgaaga aagcctaggt
361 ctcttagatg attacctgga ggtggccaag cacttcaaac ctcatgggtt ctccagcgac
421 aaggctaagg cgggctcctc cgaatggctg gctgtggatg ggttggtcag tccctccaac
481 aacagcaagg aggatgcctt ctccgggaca gattggatgt tggagaaaat ggatttgaag
541 gagttcgact tggatgccct gttgggtata gatgacctgg aaaccatgcc agatgacctt
601 ctgaccacgt tggatgacac ttgtgatctc tttgcccccc tagtccagga gactaataag
661 cagccccccc agacggtgaa cccaattggc catctcccag aaagtttaac aaaacccgac
721 caggttgccc ccttcacctt cttacaacct cttccccttt ccccaggggt cctgtcctcc
781 actccagatc attcctttag tttagagctg ggcagtgaag tggatatcac tgaaggagat
841 aggaagccag actacactgc ttacgttgcc atgatccctc agtgcataaa ggaggaagac
901 accccttcag ataatgatag tggcatctgt atgagcccag agtcctatct ggggtctcct
961 cagcacagcc cctctaccag gggctctcca aataggagcc tcccatctcc aggtgttctc
1021 tgtgggtctg cccgtcccaa accttacgat cctcctggag agaagatggt agcagcaaaa
1081 gtaaagggtg agaaactgga taagaagctg aaaaaaatgg agcaaaacaa gacagcagcc
1141 actaggtacc gccagaagaa gagggcggag caggaggctc ttactggtga gtgcaaagag
1201 ctggaaaaga agaacgaggc tctaaaagag agggcggatt ccctggccaa ggagatccag
1261 tacctgaaag atttgataga agaggtccgc aaggcaaggg ggaagaaaag ggtcccctag
1321 ttgaggatag tcaggagcgt caatgtgctt gtacatagag tgctgtagct gtgtgttcca
1381 ataaattatt ttgtagggaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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