LOCUS BC007033 1312 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1
(3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), mRNA (cDNA
clone MGC:12396 IMAGE:3683274), complete cds.
ACCESSION BC007033
VERSION BC007033.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1312)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1312)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 16 Row: k Column: 7.
FEATURES Location/Qualifiers
source 1..1312
/db_xref="H-InvDB:HIT000032998"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12396 IMAGE:3683274"
/tissue_type="Bladder, carcinoma"
/clone_lib="NIH_MGC_53"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1312
/gene="SRD5A1"
/db_xref="GeneID:6715"
/db_xref="HGNC:HGNC:11284"
/db_xref="MIM:184753"
CDS 138..917
/gene="SRD5A1"
/codon_start=1
/product="steroid-5-alpha-reductase, alpha polypeptide 1
(3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)"
/protein_id="AAH07033.1"
/db_xref="GeneID:6715"
/db_xref="HGNC:HGNC:11284"
/db_xref="MIM:184753"
/translation="MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALP
SHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIY
PFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLT
GMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQG
AAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF"
BASE COUNT 308 a 327 c 315 g 362 t
ORIGIN
1 cctttctgca gagtcccggc agtgcgggac tccggtagcc gcccctccgg tagccgcccc
61 tcctgccccc gcgccgccgc cctatatgtt gcccgccgcg gcctctgggg catggagcac
121 gctgcccagc cctggcgatg gcaacggcga cgggggtggc ggaggagcgc ctgctggccg
181 cgctcgccta cctgcagtgc gccgtgggct gcgcggtctt cgcgcggaat cgtcagacga
241 actcagtgta cggccgccac gcgctgccca gccacaggct ccgagtgccg gcgcgggccg
301 cctgggtggt gcaggagctg ccctcgctgg ccctgccgct ctaccagtac gccagcgagt
361 ccgccccgcg tctccgcagc gcgcccaact gcatcctcct ggccatgttc ctcgtccact
421 acgggcatcg gtgcttaatt tacccatttc tgatgcgagg aggaaagcct atgccactgt
481 tggcgtgtac aatggcgatt atgttctgta cctgtaacgg ctatttgcaa agcagatact
541 tgagccattg tgcagtgtat gctgatgact gggtaacaga tccccgtttt ctaataggtt
601 ttggcttgtg gttaacgggc atgttgataa acatccattc agatcatatc ctaaggaatc
661 tcagaaaacc aggagatact ggatacaaaa taccaagggg aggcttattt gaatacgtaa
721 ctgcagccaa ctattttgga gaaatcatgg agtggtgtgg ctatgccctg gccagctggt
781 ctgtccaagg cgcggctttt gctttcttca cgttttgttt tttatctggt agagcaaaag
841 agcatcatga gtggtacctc cggaaatttg aagagtatcc aaagttcaga aaaattataa
901 ttccattttt gttttaagtg cgtttttcat gaaattatct tcaacttgaa gctttccaat
961 ggcgcttctc tatggacttt gtaaataagt tatatctttg taattttcct gctactttat
1021 cattttcaag atgtcctcta ggaatttttt ttctagtaat tttgcaatct acctaataag
1081 tacctaaata cgctgaaatg gaggttgaat atcctactgt gtaacaggtc agaatttcaa
1141 gctctgggta ataactgctg atattttttc taatttcaaa tttacctctt ttggctatgt
1201 cttgccaagt gtgtatgaga ctagacttta caactgtctt tgatggcatt ttcagaacaa
1261 taaatgtcac aatcccttct agaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
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