LOCUS       Z83067                   968 bp    DNA     linear   HUM 14-NOV-2006
DEFINITION  H.sapiens Fanconi anaemia group A gene, exon 1 and joined CDS.
ACCESSION   Z83067
VERSION     Z83067.1
KEYWORDS    FAA gene; Fanconi anaemia.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1
  AUTHORS   Ianzano,L., D'Apolito,M., Centra,M., Savino,M., Levran,O.,
            Auerbach,A.D., Cleton-Jansen,A.M., Doggett,N.A., Pronk,J.C.,
            Tipping,A.J., Gibson,R.A., Mathew,C.G., Whitmore,S.A.,
            Apostolou,S., Callen,D.F., Zelante,L. and  Savoia,A.
  TITLE     The genomic organization of the Fanconi anemia group A (FAA) gene
  JOURNAL   Genomics 41(3), 309-314(1997).
   PUBMED   9169126
REFERENCE   2  (bases 1 to 968)
  AUTHORS   Savoia,A.
  JOURNAL   Submitted (08-NOV-1996) to the INSDC. Savoia A., Servizio di
            Genetica Medica, I.R.C.C.S. - Ospedale CSS, Viale Cappuccini,
            I-71013 San Giovanni Rotondo, Foggia, ITALY
COMMENT     Related sequences: Nature Genet. 14:320-323(1996), 14:324-328(1996)
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Homo sapiens"
                     /chromosome="16"
                     /map="16q24.3"
                     /mol_type="genomic DNA"
                     /clone_lib="chromosome 16 cosmid library"
                     /clone="c444B9"
                     /db_xref="taxon:9606"
     CDS             join(787..865,Z83068.1:205..314,Z83069.1:174..267,
                     Z83070.1:126..268,Z83070.1:395..490,Z83151.1:341..414,
                     Z83071.1:204..316,Z83072.1:254..336,Z83073.1:235..268,
                     Z83073.1:641..707,Z83074.1:143..255,Z83075.1:259..335,
                     Z83075.1:738..879,Z83075.1:1270..1403,Z83076.1:150..260,
                     Z83077.1:207..302,Z83077.1:391..450,Z83078.1:265..353,
                     Z83079.1:240..300,Z83079.1:393..442,Z83080.1:339..412,
                     Z83081.1:265..378,Z83082.1:332..468,Z83083.1:282..352,
                     Z83083.1:657..750,Z83083.1:892..1079,Z83084.1:232..328,
                     Z83085.1:324..500,Z83086.1:424..497,Z83087.1:234..362,
                     Z83088.1:196..280,Z83089.1:222..394,Z83090.1:308..416,
                     Z83091.1:100..159,Z83091.1:302..406,Z83092.1:273..385,
                     Z83093.1:251..389,Z83094.1:330..392,Z83095.1:164..269,
                     Z83095.1:710..785,Z83095.1:974..1130,Z83095.1:1290..1382,
                     Z83095.1:1556..1663)
                     /gene="FAA"
                     /db_xref="GDB:701221"
                     /db_xref="GOA:O15360"
                     /db_xref="HGNC:3582"
                     /db_xref="InterPro:IPR003516"
                     /db_xref="UniProtKB/Swiss-Prot:O15360"
                     /protein_id="CAB05445.1"
                     /translation="MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKE
                     SAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASR
                     LGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSR
                     LSFCQELWKIQSSLLLEAVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQME
                     ASCQHADVARAMLSDFVQMFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDAL
                     AAGVQEESSTHKIVRCWFGVFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAV
                     QMQREWSFARTHPLLTSLYRRLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVC
                     FPEAQQLLEDWVARLMAQAFESCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGS
                     TRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPSKYRSLLTDYISLAKTR
                     LADLKVSIENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRR
                     PYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDA
                     ALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDD
                     SSVEISKIQLSINTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTM
                     CGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESRSALPEVDVGPPAPGAGL
                     PVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFL
                     MFRLFSEARQPLSEEDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQ
                     DWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDGDLQAACTILVNALM
                     DFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFL
                     FEIFRRRLQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQ
                     FFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFILAKCQTKCPLI
                     LTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWL
                     SAAALHFAIQQVREENIRKQLKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKA
                     FHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAFYSLLSYFH
                     EDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLF
                     LLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQQAAPDADLSQEPHLF"
     repeat_region   1..342
                     /rpt_family="Alu"
     exon            43..865
                     /gene="FAA"
                     /number=1
     intron          866..>968
                     /number=1
BASE COUNT          191 a          327 c          325 g          124 t
ORIGIN
        1 ctgggccaac atggcgaaac gctgtctcta ctaaaaataa caaaaaatca tccaggcgtg
       61 gtggcgcgca cctgcaatcc cagctactcg ggaggctgag gcaggagaat cacctgaacc
      121 caggaggcag acgttgcagt gagccgagat cgcgccactg cactccagcc tgggcgacag
      181 agggagactc cgtctcaaaa aaaggaaaaa aaaaaaaaag aaaagaaana aaagtgatgg
      241 ggtctcgctc tgttgcccag gctagtctgg aattcctggg ctcaagcgac cctccagcct
      301 cggcctccca aagcgctggg aatacaggcg cggctaccgc gcggtctccg gctgccgaaa
      361 caccgccctg cgcgcggacc gttcggccgc cgggaggaac agcggctgcc cggagctcag
      421 aggcgcgcgc ggctttgcgc tccccgcggc gctctgagcc tgcctcggct tggttggcca
      481 ggtggtctct tcaggaccaa ccccagtcat ttcccggcag gaaccacgct tgaggggcgg
      541 cagtctgccc gcgcgagacg cccccgcgga ctacaccgcg gcggcaaagc caaaacgcag
      601 aaacgtacct caccgcgcgc aggcgcatcc cccaggacca acatggccac gacgcaaggc
      661 ctcgacatga ggggcgtggc ctggccgccg ccagccaacg ggtgtgcgcg cctggccgca
      721 gccaatagga aggcagcgcg ggctcgggcg cagggagccg ccgccggggc tgtaggcgcc
      781 aaggccatgt ccgactcgtg ggtcccgaac tccgcctcgg gccaggaccc agggggccgc
      841 cggagggcct gggccgagct gctgggtagg tgggcgcggc aggccgcggg agtgggcggc
      901 gtccggcccg ggacggtttc gccggttccc cgatcccttc ccgccagagc ctccgccggt
      961 cggatccc
//