LOCUS Z75945 340 bp mRNA linear HUM 17-JUL-1997 DEFINITION H.sapiens mRNA for T cell receptor alpha chain variable region (clone P6_40). ACCESSION Z75945 VERSION Z75945.1 KEYWORDS joining region; T cell receptor; T cell receptor alpha chain; variable region. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 AUTHORS McIntosh R.S., Watson P.F., Weetman A.P. TITLE Analysis of the T cell receptor V alpha repertoire in Hashimoto's thyroiditis: evidence for the restricted accumulation of CD8+ T cells in the absence of CD4+ T cell restriction JOURNAL J. Clin. Endocrinol. Metab. 82(4), 1140-1146(1997). PUBMED 9100586 REFERENCE 2 (bases 1 to 340) AUTHORS McIntosh R.S. JOURNAL Submitted (12-JUL-1996) to the INSDC. R.S. McIntosh, Univ. of Sheffield, Dept. of Medicine, Univ.Sheffield Clinical Sciences Centre, Northern General Hospital, Sheffield S5 7AU, UK FEATURES Location/Qualifiers source 1..340 /db_xref="H-InvDB:HIT000328112" /organism="Homo sapiens" /chromosome="14" /map="14q11.2" /isolate="patient HT139" /mol_type="mRNA" /clone_lib="TCR Valpha 6 PBL CD8+" /clone="P6_40" /cell_type="CD8+ T cells" /tissue_type="peripheral blood" /rearranged /db_xref="taxon:9606" V_region 1..340 /product="T cell receptor alpha chain variable region" V_segment 1..248 N_region 249..252 J_segment 253..306 /product="J9 region" C_region 307..>340 BASE COUNT 99 a 79 c 80 g 82 t ORIGIN 1 aaaaggaggc tgtgactctg gactgcacat atgacaccag tgatccaagt tatggtctat 61 tctggtacaa gcagcccagc agtcgggaaa tgatttttct tatttatcag gggtcttatg 121 accagcaaaa tgcaacagaa ggtcgctact cattgaattt ccagaaggca agaaaatccg 181 ccaaccttgt catctccgct tcacaactgg gggactcagc aatgtacttc tgtgcaatga 241 gagagggccg ggctggaggc ttcaaaacta tctttggagc aggaacaaga ctatttgtta 301 aagcaaatat ccagaaccct gaccctgccg tgtaccagct //