LOCUS       Z75945                   340 bp    mRNA    linear   HUM 17-JUL-1997
DEFINITION  H.sapiens mRNA for T cell receptor alpha chain variable region
            (clone P6_40).
ACCESSION   Z75945
VERSION     Z75945.1
KEYWORDS    joining region; T cell receptor; T cell receptor alpha chain;
            variable region.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1
  AUTHORS   McIntosh R.S., Watson P.F., Weetman A.P.
  TITLE     Analysis of the T cell receptor V alpha repertoire in Hashimoto's
            thyroiditis: evidence for the restricted accumulation of CD8+ T
            cells in the absence of CD4+ T cell restriction
  JOURNAL   J. Clin. Endocrinol. Metab. 82(4), 1140-1146(1997).
   PUBMED   9100586
REFERENCE   2  (bases 1 to 340)
  AUTHORS   McIntosh R.S.
  JOURNAL   Submitted (12-JUL-1996) to the INSDC. R.S. McIntosh, Univ. of
            Sheffield, Dept. of Medicine, Univ.Sheffield Clinical Sciences
            Centre, Northern General Hospital, Sheffield S5 7AU, UK
FEATURES             Location/Qualifiers
     source          1..340
                     /db_xref="H-InvDB:HIT000328112"
                     /organism="Homo sapiens"
                     /chromosome="14"
                     /map="14q11.2"
                     /isolate="patient HT139"
                     /mol_type="mRNA"
                     /clone_lib="TCR Valpha 6 PBL CD8+"
                     /clone="P6_40"
                     /cell_type="CD8+ T cells"
                     /tissue_type="peripheral blood"
                     /rearranged
                     /db_xref="taxon:9606"
     V_region        1..340
                     /product="T cell receptor alpha chain variable region"
     V_segment       1..248
     N_region        249..252
     J_segment       253..306
                     /product="J9 region"
     C_region        307..>340
BASE COUNT           99 a           79 c           80 g           82 t
ORIGIN      
        1 aaaaggaggc tgtgactctg gactgcacat atgacaccag tgatccaagt tatggtctat
       61 tctggtacaa gcagcccagc agtcgggaaa tgatttttct tatttatcag gggtcttatg
      121 accagcaaaa tgcaacagaa ggtcgctact cattgaattt ccagaaggca agaaaatccg
      181 ccaaccttgt catctccgct tcacaactgg gggactcagc aatgtacttc tgtgcaatga
      241 gagagggccg ggctggaggc ttcaaaacta tctttggagc aggaacaaga ctatttgtta
      301 aagcaaatat ccagaaccct gaccctgccg tgtaccagct
//