LOCUS       Z75940                   337 bp    mRNA    linear   HUM 17-JUL-1997
DEFINITION  H.sapiens mRNA for T cell receptor alpha chain variable region
            (clone P6_20).
ACCESSION   Z75940
VERSION     Z75940.1
KEYWORDS    joining region; T cell receptor; T cell receptor alpha chain;
            variable region.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1
  AUTHORS   McIntosh R.S., Watson P.F., Weetman A.P.
  TITLE     Analysis of the T cell receptor V alpha repertoire in Hashimoto's
            thyroiditis: evidence for the restricted accumulation of CD8+ T
            cells in the absence of CD4+ T cell restriction
  JOURNAL   J. Clin. Endocrinol. Metab. 82(4), 1140-1146(1997).
   PUBMED   9100586
REFERENCE   2  (bases 1 to 337)
  AUTHORS   McIntosh R.S.
  JOURNAL   Submitted (12-JUL-1996) to the INSDC. R.S. McIntosh, Univ. of
            Sheffield, Dept. of Medicine, Univ.Sheffield Clinical Sciences
            Centre, Northern General Hospital, Sheffield S5 7AU, UK
FEATURES             Location/Qualifiers
     source          1..337
                     /db_xref="H-InvDB:HIT000328107"
                     /organism="Homo sapiens"
                     /chromosome="14"
                     /map="14q11.2"
                     /isolate="patient HT139"
                     /mol_type="mRNA"
                     /clone_lib="TCR Valpha 6 PBL CD8+"
                     /clone="P6_20"
                     /cell_type="CD8+ T cells"
                     /tissue_type="peripheral blood"
                     /rearranged
                     /db_xref="taxon:9606"
     V_region        1..337
                     /product="T cell receptor alpha chain variable region"
     V_segment       1..235
     N_region        236..239
     J_segment       240..296
                     /product="J5 region"
     C_region        297..>337
BASE COUNT           98 a           83 c           79 g           77 t
ORIGIN      
        1 tgtgactctg gactgcacat atgacaccag tgatccaagt tatggtctat tctggtacaa
       61 gcagcccagc agtggggaaa tgatttttct tatttatcag gggtcttatg accagcaaaa
      121 tgcaacagaa ggtcgctact cattgaattt ccagaaggca agaaaatccg ccaaccctgt
      181 catctccgct tcacaactgg gggactcagc aatgtacttc tgtgcaatga gagagccata
      241 cacgggcagg agagcactta cttttgggag tggaacaaga ctccaagtgc aaccaaatat
      301 ccagaaccct gaccctgccg tgtaccagct gagagac
//