LOCUS Z75940 337 bp mRNA linear HUM 17-JUL-1997 DEFINITION H.sapiens mRNA for T cell receptor alpha chain variable region (clone P6_20). ACCESSION Z75940 VERSION Z75940.1 KEYWORDS joining region; T cell receptor; T cell receptor alpha chain; variable region. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 AUTHORS McIntosh R.S., Watson P.F., Weetman A.P. TITLE Analysis of the T cell receptor V alpha repertoire in Hashimoto's thyroiditis: evidence for the restricted accumulation of CD8+ T cells in the absence of CD4+ T cell restriction JOURNAL J. Clin. Endocrinol. Metab. 82(4), 1140-1146(1997). PUBMED 9100586 REFERENCE 2 (bases 1 to 337) AUTHORS McIntosh R.S. JOURNAL Submitted (12-JUL-1996) to the INSDC. R.S. McIntosh, Univ. of Sheffield, Dept. of Medicine, Univ.Sheffield Clinical Sciences Centre, Northern General Hospital, Sheffield S5 7AU, UK FEATURES Location/Qualifiers source 1..337 /db_xref="H-InvDB:HIT000328107" /organism="Homo sapiens" /chromosome="14" /map="14q11.2" /isolate="patient HT139" /mol_type="mRNA" /clone_lib="TCR Valpha 6 PBL CD8+" /clone="P6_20" /cell_type="CD8+ T cells" /tissue_type="peripheral blood" /rearranged /db_xref="taxon:9606" V_region 1..337 /product="T cell receptor alpha chain variable region" V_segment 1..235 N_region 236..239 J_segment 240..296 /product="J5 region" C_region 297..>337 BASE COUNT 98 a 83 c 79 g 77 t ORIGIN 1 tgtgactctg gactgcacat atgacaccag tgatccaagt tatggtctat tctggtacaa 61 gcagcccagc agtggggaaa tgatttttct tatttatcag gggtcttatg accagcaaaa 121 tgcaacagaa ggtcgctact cattgaattt ccagaaggca agaaaatccg ccaaccctgt 181 catctccgct tcacaactgg gggactcagc aatgtacttc tgtgcaatga gagagccata 241 cacgggcagg agagcactta cttttgggag tggaacaaga ctccaagtgc aaccaaatat 301 ccagaaccct gaccctgccg tgtaccagct gagagac //