LOCUS Z72499 4022 bp mRNA linear HUM 09-SEP-2004
DEFINITION H.sapiens mRNA for herpesvirus associated ubiquitin-specific
protease (HAUSP).
ACCESSION Z72499
VERSION Z72499.1
KEYWORDS ubiquitin-specific protease.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4022)
AUTHORS Everett R.D., Meredith M.R., Orr A., Cross A., Kathoria M.,
Parkinson J.
TITLE A novel ubiquitin-specific protease is dynamically associated with
the PML nuclear domain and binds to a herpesvirus regulatory
protein
JOURNAL EMBO J. 16(3), 566-577(1997).
PUBMED 9034339
REFERENCE 2 (bases 1 to 4022)
AUTHORS Everett R.D.
JOURNAL Submitted (21-MAY-1996) to the INSDC. Everett R.D., MRC Virology
Unit Church Street Glasgow United Kingdom G11 5JR
FEATURES Location/Qualifiers
source 1..4022
/db_xref="H-InvDB:HIT000327987"
/organism="Homo sapiens"
/mol_type="mRNA"
/sex="female"
/clone_lib="lambda ZAP"
/cell_line="HeLa"
/cell_type="fibroblast"
/db_xref="taxon:9606"
CDS 200..3508
/product="herpesvirus associated ubiquitin-specific
protease (HAUSP)"
/db_xref="GOA:Q93009"
/db_xref="H-InvDB:HIT000327987.14"
/db_xref="HGNC:HGNC:12630"
/db_xref="InterPro:IPR001394"
/db_xref="InterPro:IPR002083"
/db_xref="InterPro:IPR008974"
/db_xref="InterPro:IPR018200"
/db_xref="InterPro:IPR024729"
/db_xref="InterPro:IPR028889"
/db_xref="InterPro:IPR029346"
/db_xref="InterPro:IPR038765"
/db_xref="PDB:1NB8"
/db_xref="PDB:1NBF"
/db_xref="PDB:1YY6"
/db_xref="PDB:1YZE"
/db_xref="PDB:2F1W"
/db_xref="PDB:2F1X"
/db_xref="PDB:2F1Y"
/db_xref="PDB:2F1Z"
/db_xref="PDB:2FOJ"
/db_xref="PDB:2FOO"
/db_xref="PDB:2FOP"
/db_xref="PDB:2KVR"
/db_xref="PDB:2XXN"
/db_xref="PDB:2YLM"
/db_xref="PDB:3MQR"
/db_xref="PDB:3MQS"
/db_xref="PDB:4JJQ"
/db_xref="PDB:4KG9"
/db_xref="PDB:4M5W"
/db_xref="PDB:4M5X"
/db_xref="PDB:4PYZ"
/db_xref="PDB:4WPH"
/db_xref="PDB:4WPI"
/db_xref="PDB:4YOC"
/db_xref="PDB:4YSI"
/db_xref="PDB:4Z96"
/db_xref="PDB:4Z97"
/db_xref="PDB:5C56"
/db_xref="PDB:5C6D"
/db_xref="PDB:5FWI"
/db_xref="PDB:5GG4"
/db_xref="PDB:5J7T"
/db_xref="PDB:5JTJ"
/db_xref="PDB:5JTV"
/db_xref="PDB:5KYB"
/db_xref="PDB:5KYC"
/db_xref="PDB:5KYD"
/db_xref="PDB:5KYE"
/db_xref="PDB:5KYF"
/db_xref="PDB:5N9R"
/db_xref="PDB:5N9T"
/db_xref="PDB:5NGE"
/db_xref="PDB:5NGF"
/db_xref="PDB:5UQV"
/db_xref="PDB:5UQX"
/db_xref="PDB:5VS6"
/db_xref="PDB:5VSB"
/db_xref="PDB:5VSK"
/db_xref="PDB:5WHC"
/db_xref="PDB:6F5H"
/db_xref="UniProtKB/Swiss-Prot:Q93009"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAA96580.1"
/translation="MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVING
NVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVM
PRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFH
KENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKN
QGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGT
KKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQC
KEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKG
VKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYIL
HAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVR
HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQ
VQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWP
MQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKD
HDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKP
NLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIF
CDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHN
YEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDK
HGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRI
EEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDI
QEKEFEKFKFAIVMTGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKR
SRYTYLEKAIKIHN"
polyA_site 4013
BASE COUNT 1183 a 845 c 1012 g 982 t
ORIGIN
1 gtacgtgcgc gtctccctgc cgccgccgcc gcccgccgcg ggccgccccg gggccgccgt
61 cgccgacgac gcgcgggagg aggaggagga ggccgccccg ccgccgccgc cgccgccgcc
121 gccccggctc gccgccgccc gcccgccggg ctcgcagccc cggcccccgg ccgcaggcga
181 ggcccaggcc gcggccgaca tgaaccacca gcagcagcag cagcagcaga aagcgggcga
241 gcagcagttg agcgagcccg aggacatgga gatggaagcg ggagatacag atgacccacc
301 aagaattact cagaaccctg tgatcaatgg gaatgtggcc ctgagtgatg gacacaacac
361 cgcggaggag gacatggagg atgacaccag ttggcgctcc gaggcaacct ttcagttcac
421 tgtggagcgc ttcagcagac tgagtgagtc ggtccttagc cctccgtgtt ttgtgcgaaa
481 tctgccatgg aagattatgg tgatgccacg cttttatcca gacagaccac accaaaaaag
541 cgtaggattc tttctccagt gcaatgctga atctgattcc acgtcatggt cttgccatgc
601 acaagcagtg ctgaagataa taaattacag agatgatgaa aagtcgttca gtcgtcgtat
661 tagtcatttg ttcttccata aagaaaatga ttggggattt tccaatttta tggcctggag
721 tgaagtgacc gatcctgaga aaggatttat agatgatgac aaagttacct ttgaagtctt
781 tgtacaggcg gatgctcccc atggagttgc gtgggattca aagaagcaca caggctacgt
841 cggcttaaag aatcagggag cgacttgtta catgaacagc ctgctacaga cgttattttt
901 cacgaatcag ctacgaaagg ctgtgtacat gatgccaacc gagggggatg attcgtctaa
961 aagcgtccct ttagcattac aaagagtgtt ctatgaatta cagcatagtg ataaacctgt
1021 aggaacaaaa aagttaacaa agtcatttgg gtgggaaact ttagatagct tcatgcaaca
1081 tgatgttcag gagctttgtc gagtgttgct cgataatgtg gaaaataaga tgaaaggcac
1141 ctgtgtagag ggcaccatac ccaaattatt ccgcggcaaa atggtgtcct atatccagtg
1201 taaagaagta gactatcggt ctgatagaag agaagattat tatgatatcc agctaagtat
1261 caaaggaaag aaaaatatat ttgaatcatt tgtggattat gtggcagtag aacagctcga
1321 tggggacaat aaatacgacg ctggggaaca tggcttacag gaagcagaga aaggtgtgaa
1381 attcctaaca ttgccaccag tgttacatct acaactgatg agatttatgt atgaccctca
1441 gacggaccaa aatatcaaga tcaatgatag gtttgaattc ccagagcagt taccacttga
1501 tgaatttttg caaaaaacag atcctaagga ccctgcaaat tatattcttc atgcagtcct
1561 ggttcatagt ggagataatc atggtggaca ttatgtggtt tatctaaacc ccaaagggga
1621 tggcaaatgg tgtaaatttg atgacgacgt ggtgtcaagg tgtactaaag aggaagcaat
1681 tgagcacaat tatgggggtc acgatgacga cctgtctgtt cgacactgca ctaatgctta
1741 catgttagtc tacatcaggg aatcaaaact gagtgaagtt ttacaggcgg tcaccgacca
1801 tgatattcct cagcagttgg tggagcgatt acaagaagag aaaaggatcg aggctcagaa
1861 gcggaaggag cggcaggaag cccatctcta tatgcaagtg cagatagtcg cagaggacca
1921 gttttgtggc caccaaggga atgacatgta cgatgaagaa aaagtgaaat acactgtgtt
1981 caaagtattg aagaactcct cgcttgctga gtttgttcag agcctctctc agaccatggg
2041 atttccacaa gatcaaattc gattgtggcc catgcaagca aggagtaatg gaacaaaacg
2101 accagcaatg ttagataatg aagccgacgg caataaaaca atgattgagc tcagtgataa
2161 tgaaaaccct tggacaatat tcctggaaac agttgatccc gagctggctg ctagtggagc
2221 gaccttaccc aagtttgata aagatcatga tgtaatgtta tttttgaaga tgtatgatcc
2281 caaaacgcgg agcttgaatt actgtgggca tatctacaca ccaatatcct gtaaaatacg
2341 tgacttgctc ccagttatgt gtgacagagc aggatttatt caagatacta gccttatcct
2401 ctatgaggaa gttaaaccga atttaacaga gagaattcag gactatgacg tgtctcttga
2461 taaagccctt gatgaactaa tggatggtga catcatagta tttcagaagg atgaccctga
2521 aaatgataac agtgaattac ccaccgcaaa ggagtatttc cgagatctct accaccgcgt
2581 tgatgtcatt ttctgtgata aaacaatccc taatgatcct ggatttgtgg ttacgttatc
2641 aaatagaatg aattattttc aggttgcaaa gacagttgca cagaggctca acacagatcc
2701 aatgttgctg cagtttttca agtctcaagg ttatagggat ggcccaggta atcctcttag
2761 acataattat gaaggtactt taagagatct tctacagttc ttcaagccta gacaacctaa
2821 gaaactttac tatcagcagc ttaagatgaa aatcacagac tttgagaaca ggcgaagttt
2881 taaatgtata tggttaaaca gccaatttag ggaagaggaa ataacactat atccagacaa
2941 gcatgggtgt gtccgggacc tgttagaaga atgtaaaaag gccgtggagc ttggggagaa
3001 agcatcaggg aaacttaggc tgctagaaat tgtaagctac aaaatcattg gtgttcatca
3061 agaagatgaa ctattagaat gtttatctcc tgcaacgagc cggacgtttc gaatagagga
3121 aatccctttg gaccaggtgg acatagacaa agagaatgag atgcttgtca cagtggcgca
3181 tttccacaaa gaggtcttcg gaacgttcgg aatcccgttt ttgctgagga tacaccaggg
3241 cgagcatttt cgagaagtga tgaagcgaat ccagagcctg ctggacatcc aggagaagga
3301 gtttgagaag tttaaatttg caattgtaat gacgggccga caccagtaca taaatgaaga
3361 cgagtatgaa gtaaatttga aagactttga gccacagccc ggtaatatgt ctcatcctcg
3421 gccttggcta gggctcgacc acttcaacaa agccccaaag aggagtcgct acacttacct
3481 tgaaaaggcc attaaaatcc ataactgatt tccaagctgg tgtgttcaag gcgaggacgg
3541 tgtgtgggtg gccccttaac agcctagaac tttggtgcac gtgccctcta gccgaagtct
3601 tcagcaagag gattcgctgc tggtgttaat tttattttat tgaggctgtt cagtttggct
3661 tctctgtatc tattgactgc cctttttgag caaaatgaag atgtttttat aaagcttgga
3721 tgccaatgag agttatttta tggtaaccac agtgcaaggc aactgtcagc gcaatggggg
3781 agaagaggtt agtggatcgg gggtccctgg ctcaaggtct ctgggctgtc cctagtgggc
3841 acgagtggct cggctgcctt cctggggtcc cgtgcaccag ccctgcagct agcaagtctt
3901 gtgtttaggc tcgtctgacc tatttccttc agttatactt tcaatgacct tttgtgcatc
3961 tgttaaggca aaacagagaa actcacaacc taataaatag cgctcttccc ttcaaaaaaa
4021 aa
//