LOCUS Z69028 2183 bp mRNA linear HUM 07-OCT-1996
DEFINITION H.sapiens mRNA for beta 2 isoform of 61 kDa regulatory subunit of
PP2A.
ACCESSION Z69028
VERSION Z69028.1
KEYWORDS 61kDa regulatory subunit; beta 2 isoform; PP2A gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2183)
AUTHORS Zolnierowicz S., Van Hoof C., Andjelkovic N., Cron P., Stevens I.,
Merlevede W., Goris J., Hemmings B.A.
TITLE The variable subunit associated with protein phosphatase 2A0
defines a novel multimember family of regulatory subunits.
JOURNAL Biochem. J. 317, 187-194(1996).
PUBMED 8694763
REFERENCE 2 (bases 1 to 2183)
AUTHORS Hemmings B.B.A.
JOURNAL Submitted (27-JAN-1996) to the INSDC. Hemmings B.B.A., Friedrich
Miescher-Institut, Maulbeerstrasse 66, BASEL, Switzerland, CH-4002
FEATURES Location/Qualifiers
source 1..2183
/db_xref="H-InvDB:HIT000327665"
/organism="Homo sapiens"
/isolate="17-18 weeks gestation"
/mol_type="mRNA"
/sex="female"
/dev_stage="Fetus"
/clone_lib="cDNA library (Stratagene)"
/clone="PR61-P14"
/tissue_type="Brain"
/db_xref="taxon:9606"
5'UTR 1..69
CDS 70..1554
/product="beta 2 isoform of 61kDa regulatory subunit of
PP2A"
/db_xref="GOA:Q15173"
/db_xref="H-InvDB:HIT000327665.11"
/db_xref="HGNC:HGNC:9310"
/db_xref="InterPro:IPR002554"
/db_xref="InterPro:IPR011989"
/db_xref="InterPro:IPR016024"
/db_xref="UniProtKB/Swiss-Prot:Q15173"
/protein_id="CAA93152.1"
/translation="MITVNPPLPQDTVNLFSPVPPPDKVDGFSRRSLRRARPRRSHSS
SQFRYQSNQQELTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRA
ALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWP
HLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVY
GKFLGLRAYIRKQCNHIFLRFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLV
RVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLG
EMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCH
TVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQK
AQERQELWQGLEELRLRRLQGTQGAKEAPLQRLTPQVAASGGQS"
3'UTR 1555..2183
BASE COUNT 458 a 645 c 597 g 483 t
ORIGIN
1 gaattccttt tttttgaatt tctctcttta attaaggtct accccaagcc acggaaagag
61 gagtagacca tgattactgt gaaccccccc ttaccccagg acactgtgaa tctcttctcg
121 cctgtgcccc cacccgacaa ggtggacggc ttctcccgcc gttccctccg cagagcccgg
181 ccccgccgct cccacagctc ctctcagttc cgctatcaga gcaaccagca agagctcaca
241 ccgctgcccc tgctcaaaga tgtgccggct tccgagctgc acgagctgct gagccggaag
301 ctggcccagt gtggggtgat gtttgacttc ttggactgtg tggccgacct caaggggaag
361 gaggtgaagc gggcagccct caacgagctg gtggagtgtg tggggagcac ccggggtgtc
421 ctcatcgagc ccgtctaccc agacatcatc cgcatgatct cagtgaatat cttccggact
481 ctgccgccca gtgagaaccc tgaatttgac cctgaagagg atgagcccaa tcttgagcct
541 tcgtggccac acctgcagct ggtatatgag tttttcctgc gtttcttgga gagcccagac
601 ttccagccct ccgtggccaa gagatatgtg gatcaaaagt ttgtcctgat gctcctggag
661 ctatttgata gtgaggatcc ccgggagcgt gagtacctca agaccatcct gcaccgggtc
721 tatggcaagt tcctgggtct ccgggcctac atccgcaaac agtgcaacca catcttcctc
781 cggttcatct atgaattcga gcacttcaat ggtgtggctg agctgctgga gatcctagga
841 agcatcatca atggctttgc gctgcccctg aagacggagc acaagcagtt cctggttcgc
901 gtcctgatcc ccctgcactc tgtcaagtcg ctgtctgtct tccatgccca gctggcatac
961 tgtgtggtgc agttcctgga gaaggatgcc actctgacag agcacgtgat ccgggggctg
1021 ctcaaatact ggccaaaaac ctgcacccag aaggaggtga tgtttctggg ggagatggaa
1081 gagattcttg atgtcatcga gccctcccag tttgtgaaga tccaggagcc cctttttaag
1141 caggtggctc gctgtgtttc cagcccccat ttccaggttg cagagcgggc tctgtatttc
1201 tggaacaatg agtatatcct aagcctcatt gaggacaact gccacactgt gctgcctgct
1261 gtgtttggga ccctctacca agtctccaag gagcactgga accaaaccat cgtatcactg
1321 atctacaatg tgctcaagac cttcatggag atgaatggga agctgtttga tgagctcaca
1381 gcctcctaca agctggaaaa gcagcaggag cagcagaagg cccaggagcg tcaggagtta
1441 tggcaaggtc tggaggagct gcggctacgc cggctacagg ggacccaggg ggccaaggag
1501 gcccccctcc agcggcttac accccaggtg gccgccagtg ggggtcagag ctagacagca
1561 cctcagaagg ggaaaagcta aacccagagc tgtcagtccc tctatccctt ctcctgtcca
1621 ggggcccaga gagaaacaca cctacccctg gccttgccag agtggcttct gaggactccc
1681 agcccagccc agctttcact ggggggagac gaggagaggc aatggtggtc ttggcaacag
1741 aatgctcagc ccctcgtggc aggacttgac aagggcaagc ttgaccagga agctgccatc
1801 agggatcttc ccctgccccg caaagctagg ctccagctgc aggcgggctc ccaccctctg
1861 ctcctggcct tgggcaaggg cactcagcgc ctcgcctgcc cctgccttgg ccaatgcgag
1921 gtccttcctt atccccacca tggggtccat ggtctattta ttctcgccca gctcaccctc
1981 tacacagaca ctgtcctggg tgcacactcc tcccttccct cgctgtgtac ttccttgtcc
2041 cctttttatt tattgggcag ggggaggggg agggcacagg caagaagaga ttcacagtgt
2101 cctggggtaa gggggggttc acagtaatca tggtctactc ctctttccgt ggctgggggt
2161 agacttaata aagagagaaa ttc
//