LOCUS Z48923 3871 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for BMPR-II.
ACCESSION Z48923
VERSION Z48923.1
KEYWORDS BMPR-II.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3871)
AUTHORS Rosenzweig B.L., Imamura T., Okadome T., Cox G.N., Yamashita H.,
ten Dijke P., Heldin C.H., Miyazono K.
TITLE Cloning and characterization of a human type II receptor for bone
morphogenetic proteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92(17), 7632-7636(1995).
PUBMED 7644468
REFERENCE 2 (bases 1 to 3871)
AUTHORS Miyazono K.
JOURNAL Submitted (30-MAR-1995) to the INSDC. Kohei Miyazono, Ludwig
Institute for Cancer Research, Biomedical Center, Uppsala, S-751
24, Sweden
FEATURES Location/Qualifiers
source 1..3871
/db_xref="H-InvDB:HIT000327437"
/organism="Homo sapiens"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="substantia nigra lambda gt10 cDNA library"
/tissue_type="substantia nigra"
/db_xref="taxon:9606"
5'UTR 1..381
CDS 382..3498
/product="BMPR-II precursor"
/db_xref="GOA:Q13873"
/db_xref="H-InvDB:HIT000327437.14"
/db_xref="HGNC:HGNC:1078"
/db_xref="InterPro:IPR000333"
/db_xref="InterPro:IPR000472"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR015770"
/db_xref="InterPro:IPR017441"
/db_xref="PDB:2HLQ"
/db_xref="PDB:3G2F"
/db_xref="UniProtKB/Swiss-Prot:Q13873"
/protein_id="CAA88759.1"
/translation="MTSSLQRPWRVPWLPWTILLVSTAAASQNQERLCAFKDPYQQDL
GIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVT
TTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDETIIIALASVSV
LAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAASEPSLDLDNLKLLELIGRGRYGAVY
KGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYL
LVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDL
NSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAV
NLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQ
VLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIW
ERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNI
SSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPST
GMTTISEMPYPDETNLHTTNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSD
ENLMEHSLKQFSGPDPLSSTSSSLLYPLIKLAVEATGQQDFTQTANGQACLIPDVLPT
QIYPLPKQQNLPKRPTSLPLNTKNSTKEPRLKFGSKHKSNLKQVETGVAKMNTINAAE
PHVVTVTMNGVAGRNHSVNSHAATTQYANRTVLSGQTTNIVTHRAQEMLQNQFIGEDT
RLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPCSEQD
VLAQGVPSTAADPGPSKPRRAQRPNSLDLSATNVLDGSSIQIGESTQDGKSGSGEKIK
KRVKTPYSLKRWRPSTWVISTESLDCEVNNNGSNRAVHSKSSTAVYLAEGGTATTMVS
KDIGMNCL"
mat_peptide 457..3495
/product="BMPR-II"
3'UTR 3499..3871
BASE COUNT 1119 a 909 c 914 g 929 t
ORIGIN
1 ggcctccgca ccctggatat gttttctccc agacctggat atttttttga tatcgtgaaa
61 ctacgaggga aataatttgg gggatttctt cttggctccc tgctttcccc acagacatac
121 cttccgtttg gagggccgcg gcaccccgtc cgaggcgaag gaaccccccc atccgcgagg
181 gagagaaatg aagggaattt ctgcagcggc atgaaagctc tgcagctagg tcctctcatc
241 agccatttgt cctttcaaac tgtattgtga tacgggcagg atcagtccac gggagagaag
301 acgagcctcc cggctgtttc tccgccggtc tacttcccat atttcttttc tttgccctcc
361 tgattcttgg ctggcccagg gatgacttcc tcgctgcagc ggccctggcg ggtgccctgg
421 ctaccatgga ccatcctgct ggtcagcact gcggctgctt cgcagaatca agaacggcta
481 tgtgcgttta aagatccgta tcagcaagac cttgggatag gtgagagtag aatctctcat
541 gaaaatggga caatattatg ctcgaaaggt agcacctgct atggcctttg ggagaaatca
601 aaaggggaca taaatcttgt aaaacaagga tgttggtctc acattggaga tccccaagag
661 tgtcactatg aagaatgtgt agtaactacc actcctccct caattcagaa tggaacatac
721 cgtttctgct gttgtagcac agatttatgt aatgtcaact ttactgagaa ttttccacct
781 cctgacacaa caccactcag tccacctcat tcatttaacc gagatgagac aataatcatt
841 gctttggcat cagtctctgt attagctgtt ttgatagttg ccttatgctt tggatacaga
901 atgttgacag gagaccgtaa acaaggtctt cacagtatga acatgatgga ggcagcagca
961 tccgaaccct ctcttgatct agataatctg aaactgttgg agctgattgg ccgaggtcga
1021 tatggagcag tatataaagg ctccttggat gagcgtccag ttgctgtaaa agtgttttcc
1081 tttgcaaacc gtcagaattt tatcaacgaa aagaacattt acagagtgcc tttgatggaa
1141 catgacaaca ttgcccgctt tatagttgga gatgagagag tcactgcaga tggacgcatg
1201 gaatatttgc ttgtgatgga gtactatccc aatggatctt tatgcaagta tttaagtctc
1261 cacacaagtg actgggtaag ctcttgccgt cttgctcatt ctgttactag aggactggct
1321 tatcttcaca cagaattacc acgaggagat cattataaac ctgcaatttc ccatcgagat
1381 ttaaacagca gaaatgtcct agtgaaaaat gatggaacct gtgttattag tgactttgga
1441 ctgtccatga ggctgactgg aaatagactg gtgcgcccag gggaggaaga taatgcagcc
1501 ataagcgagg ttggcactat cagatatatg gcaccagaag tgctagaagg agctgtgaac
1561 ttgagggact gtgaatcagc tttgaaacaa gtagacatgt atgctcttgg actaatctat
1621 tgggagatat ttatgagatg tacagacctc ttcccagggg aatccgtacc agagtaccag
1681 atggcttttc agacagaggt tggaaaccat cccacttttg aggatatgca ggttctcgtg
1741 tctagggaaa aacagagacc caagttccca gaagcctgga aagaaaatag cctggcagtg
1801 aggtcactca aggagacaat cgaagactgt tgggaccagg atgcagaggc tcggcttact
1861 gcacagtgtg ctgaggaaag gatggctgaa cttatgatga tttgggaaag aaacaaatct
1921 gtgagcccaa cagtcaatcc aatgtctact gctatgcaga atgaacgcaa cctgtcacat
1981 aataggcgtg tgccaaaaat tggtccttat ccagattatt cttcctcctc atacattgaa
2041 gactctatcc atcatactga cagcatcgtg aagaatattt cctctgagca ttctatgtcc
2101 agcacacctt tgactatagg ggaaaaaaac cgaaattcaa ttaactatga acgacagcaa
2161 gcacaagctc gaatccccag ccctgaaaca agtgtcacca gcctctccac caacacaaca
2221 accacaaaca ccacaggact cacgccaagt actggcatga ctactatatc tgagatgcca
2281 tacccagatg aaacaaatct gcataccaca aatgttgcac agtcaattgg gccaacccct
2341 gtctgcttac agctgacaga agaagacttg gaaaccaaca agctagaccc aaaagaagtt
2401 gataagaacc tcaaggaaag ctctgatgag aatctcatgg agcactctct taaacagttc
2461 agtggcccag acccactgag cagtactagt tctagcttgc tttacccact cataaaactt
2521 gcagtagaag caactggaca gcaggacttc acacagactg caaatggcca agcatgtttg
2581 attcctgatg ttctgcctac tcagatctat cctctcccca agcagcagaa ccttcccaag
2641 agacctacta gtttgccttt gaacaccaaa aattcaacaa aagagccccg gctaaaattt
2701 ggcagcaagc acaaatcaaa cttgaaacaa gtcgaaactg gagttgccaa gatgaataca
2761 atcaatgcag cagaacctca tgtggtgaca gtcaccatga atggtgtggc aggtagaaac
2821 cacagtgtta actcccatgc tgccacaacc caatatgcca ataggacagt actatctggc
2881 caaacaacca acatagtgac acatagggcc caagaaatgt tgcagaatca gtttattggt
2941 gaggacaccc ggctgaatat taattccagt cctgatgagc atgagccttt actgagacga
3001 gagcaacaag ctggccatga tgaaggtgtt ctggatcgtc ttgtggacag gagggaacgg
3061 ccactagaag gtggccgaac taattccaat aacaacaaca gcaatccatg ttcagaacaa
3121 gatgttcttg cacagggtgt tccaagcaca gcagcagatc ctgggccatc aaagcccaga
3181 agagcacaga ggcctaattc tctggatctt tcagccacaa atgtcctgga tggcagcagt
3241 atacagatag gtgagtcaac acaagatggc aaatcaggat caggtgaaaa gatcaagaaa
3301 cgtgtgaaaa ctccctattc tcttaagcgg tggcgcccct ccacctgggt catctccact
3361 gaatcgctgg actgtgaagt caacaataat ggcagtaaca gggcagttca ttccaaatcc
3421 agcactgctg tttaccttgc agaaggaggc actgctacaa ccatggtgtc taaagatata
3481 ggaatgaact gtctgtgaaa tgttttcaag cctatggagt gaaattattt tttgcatcat
3541 ttaaacatgc agaagatgtt taccgggcgg ggtgacagga gagagcgtca gcggcaagct
3601 gtggaggatg gggctcagaa tgcagacctg ggctggccgc atggcctctc cctgagccct
3661 gatttgtggt agggaagcag tatgggtgca gtcccctcct aggcctccct ctggggtccc
3721 ccgatcctat cccacctctt cagggtgagc cagcctcacc tcttcctagt cctgagggtg
3781 agggcaggct gaggcaacga gtgggaggtt caaacaagag tgggctggag ccaagggaaa
3841 atagagatga tgtaatttct ttccggaatt c
//