LOCUS Z35309 6005 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for adenylyl cyclase.
ACCESSION Z35309
VERSION Z35309.1
KEYWORDS adenylyl cyclase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6005)
AUTHORS Defer N., Marinx O., Stengel D., Danisova A., Iourgenko V.,
Matsuoka I., Caput D., Hanoune J.
TITLE Molecular cloning of the human type VIII adenylyl cyclase
JOURNAL FEBS Lett. 351(1), 109-113(1994).
PUBMED 8076676
REFERENCE 2 (bases 1 to 6005)
AUTHORS Defer N.
JOURNAL Submitted (21-JUL-1994) to the INSDC. Nicole Defer, Inserm U99,
Hopital Henri Mondor, CRETEIL F-94010, France
FEATURES Location/Qualifiers
source 1..6005
/db_xref="H-InvDB:HIT000327026"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="cDNA library"
/tissue_type="newborn brain stem"
/db_xref="taxon:9606"
CDS 2095..5850
/product="adenylyl cyclase"
/EC_number="4.6.1.1"
/db_xref="GOA:P40145"
/db_xref="H-InvDB:HIT000327026.15"
/db_xref="HGNC:HGNC:239"
/db_xref="InterPro:IPR001054"
/db_xref="InterPro:IPR009398"
/db_xref="InterPro:IPR018297"
/db_xref="InterPro:IPR029787"
/db_xref="InterPro:IPR030672"
/db_xref="InterPro:IPR032628"
/db_xref="UniProtKB/Swiss-Prot:P40145"
/protein_id="CAA84552.1"
/translation="MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRH
ITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHS
TCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNS
FKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGF
FTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLF
TLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTA
GIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTN
VEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLA
HEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRI
GIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVE
EGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWS
PELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDK
LRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMP
MTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFL
GAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSV
LKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFY
HGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEE
LYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDI
EKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELR
IGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFA
FDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLN
RQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP"
regulatory 5901..5906
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1342 a 1760 c 1614 g 1289 t
ORIGIN
1 gactggctgc agccgcagtc ttggtggagg aggtggtgac caccaccgct cctccacctg
61 catccggctg cgggactgcg gcggccgcgt ttgccctgca gaccctgcac cccgggacgc
121 ggctcatctg tcattagcac cggcactaag ctcccaccgc tcagcgactt ggtccgccgc
181 aagctccgcc gcaggctttg tccgctagcg ctcggctgag tctgggcggg cgggaaacct
241 gggctagggc gaggcggggc ccctggacat gcctttctcc acgtccgcct cctcgaccct
301 attgtaagcg gagaaactta gtgtgcgagg caggcagggg acgtccccat tttgatgtcc
361 cgtaccctcc acccccttcg gatcgaggta gtaaagaggc tcctgtagga aactgactgc
421 ctctatgatt gcggcctctt gggggatttt gcgtttagcc cgaaagttgg ctttgccaaa
481 agacgcacgg gtaggaaggg cgaaaaggaa accctgtatt ccgtcgcgct gggctctccg
541 agtccgtgcg caaagcggcc tacgagtcct ggctccgcac ctgcagagga caagagccaa
601 tgcctaaaaa agaacagcgg aggaaccggc tggcgcggcc agctggaacg ctggatcgca
661 gtgcgcccag ggaaggccgg gggcgcccgc cggccctagc cctcagtggt cctctcccac
721 gccggcccgc gcgtgcctct gcctacaaga cctggggcgt cctggccaga tctggatggc
781 aggtccctcc gccacccccg gcccggttcc gggggcgtgg cttggcgcgg gggcgggttt
841 aagtcaccgc gggtgtctga ccactctgac aggtctccaa atttctccca gtcgcctggc
901 gcccgcggtg cgtttcagag ctccagggtg gcacgcggcg gcgcttccct agatccagag
961 gcgtctctgt cgacttccac gcggcctcgg gcctcccttc tcctccaaac cttcgcctca
1021 tccgccaagc ttcggttctc agcctcagat atccgcaccg gcggcttctc ttcgttctcg
1081 gagctcttgg ctttggagcc ctcaccactt tttccttccc ccgcctctcc tgatcctcct
1141 agctccgagc caaatggact ccaaagaacg aaataaaggg gatgagaact gtgtgctgcg
1201 acccttcgaa agcacagctg aaagcgttga cctcgtctta tagatcaggc tgggaccctg
1261 gggcgagagt ccccacaccc cctccgggag ggatgcttct ggccagagcc agcgctgcgc
1321 tgtcagtcct tgctcccgaa ctaggaaaga gcctaggagg gagcctcagc ataccccttc
1381 ctccaaatta actatttggt gaattgttag cgccgaggct accacctctc caaccctgtc
1441 gcggggcgcg ccgccacctc accgtgaccc cctcctcctc cttctttgcc accgccccca
1501 gctccgcccc tgctccccat cccggcgcaa tggagttctc cgaagggcga tgattccagc
1561 cacatctgct aacttcgcac ccatcgctgc cgccggtcac cgccggccag gccccctgca
1621 gccgcggagc agtgggcgtc caaagcccag tgcagcagcc aggacccgcc cgacgcgcag
1681 cagaagcacg gcgcccaggc gcttaggcgt ctcttggaga gcaaaggctg cgccaaaacg
1741 ctgagcctag aatcaaccaa ggagcctgag cccaggaagg ggctgcgtgg ctcacagcgc
1801 tgcggctcct gaggacaaat agccactgcc gctgcgtacc caagctgcgc cggctggcgg
1861 gagagcagca cgcaaggacg ccgaggtccg ccgcgatctt ccaggtgccc tttgcccctg
1921 ggcacagtat gacccgacct acagggagcc ctagcgcagg gctcctgcaa cgggtcagcc
1981 taggataaaa aggatccttg ccaagctcct accaggccgc ctttgagtct ttaggaaccc
2041 ctcctccggc tgcctcccca aggttctggg cctccttccc tgcggcccag agccatggag
2101 ctctccgatg tgcgctgcct tacaggcagc gaggaactct acaccatcca cccgacgccc
2161 ccggccggcg acggcaggag cgcctcccgg ccgcagcggc tgctgtggca gacggcggtg
2221 cgacacatca cggagcagcg cttcattcac gggcaccggg gaggcagcgg cagcgggagt
2281 ggaggctcgg gcaaagcctc ggaccctgcg ggcggcggcc ccaaccacca cgcgccgcag
2341 ctgtcaggcg actcggcgct gcccctctac tcgctgggcc cgggagagcg agcgcacagc
2401 acctgcggca ccaaagtctt cccggaacgc agcgggagcg gcagtgccag cggcagcgga
2461 ggcgggggcg acctgggctt cctgcacctt gactgtgccc ctagcaactc ggatttcttt
2521 cttaatgggg gctatagcta ccgaggggtc attttcccca ccctgcgcaa ctccttcaaa
2581 tctcgggatt tggaacgcct ctaccagcgc tatttcttgg gccaaaggcg caaatcggaa
2641 gtggtgatga acgtgctgga cgtgctgacc aaactcactc tcttggtcct acacttgagc
2701 ctggcctcgg cccccatgga cccgctcaag ggcatcctgc tgggcttctt caccggcatt
2761 gaggtagtga tctgcgccct ggtggtggtc aggaaggaca ccacctccca cacgtacctg
2821 cagtacagcg gcgtggtcac ctgggtggcc atgaccaccc agatcctggc agcaggcctc
2881 ggctacgggc tcctgggcga cggcataggc tacgtgctct tcacgctctt cgccacctac
2941 agtatgctgc cgctgccgct cacctgggcc atcctggccg gcctgggcac ctcgctgctg
3001 caggtcatcc tccaagtggt cataccccgg ctggcggtca tttccatcaa ccaggttgtg
3061 gcccaggcag tgctattcat gtgtatgaac acagctggaa tcttcatcag ttacctgtca
3121 gaccgggccc agcgccaagc tttcctggag actcggaggt gtgtggaggc caggctgcgc
3181 ctggagacag agaaccaaag acaggagcgg ctcgtgcttt ctgtgctccc ccggtttgtt
3241 gtcctggaaa tgatcaacga catgaccaat gtggaagatg agcacctgca gcaccagttc
3301 catcggatct acatccatcg ctatgagaac gtcagtattc tttttgcaga tgttaaagga
3361 tttaccaacc tctccacgac cttgtctgct caggagctgg tcaggatgct caacgagctc
3421 tttgccagat ttgatcgact ggcccatgag catcactgcc ttcgtattaa aatcctgggg
3481 gactgctact actgcgtgtc tggacttcct gagccccgcc aggaccatgc ccactgctgt
3541 gttgaaatgg gtctcagcat gatcaaaacc atcaggtatg tgcggtcaag gacaaaacac
3601 gatgttgaca tgaggattgg aatccactcc ggctcggtgc tgtgcggtgt tttgggacta
3661 cggaagtggc agtttgatgt ctggtcttgg gatgtggata ttgcaaacaa actcgaatct
3721 ggaggaatcc ccgggaggat tcacatttcc aaagccacgc tggactgtct caacggtgac
3781 tataacgtgg aagagggcca tggtaaagag aggaatgaat tcctgaggaa gcataatatc
3841 gaaacttact taattaagca gcctgaggac agtctgctgt ccttgcctga agatatcgtc
3901 aaggagtcag tgagctcctc agaccggaga aacagtgggg ccacattcac tgaaggatcc
3961 tggagccctg aactgccctt tgataatatc gtggggaaac agaatactct ggctgcccta
4021 acaagaaatt caataaatct gcttccaaac catcttgcac aagctttgca tgtccagtct
4081 gggcctgagg aaattaacaa gagaatagaa cataccatcg acttgcggag tggcgataaa
4141 ttgagaagag agcatatcaa gccattctca ctgatgttta aagactccag cctggagcac
4201 aagtattctc aaatgaggga tgaagtgttc aagtcaaact tggtctgtgc atttatcgtt
4261 cttctattta tcacggcaat acaaagtttg cttccttctt caagagtgat gccaatgacc
4321 atccagttct ccattctgat tatgctgcac tcggctctgg tcctcatcac cacagcagag
4381 gattataaat gtttgcccct catcctccgg aaaacttgct gttggattaa tgagacctat
4441 ttggcccgga acgtcatcat ctttgcatcc attttgatta atttcctggg tgccatctta
4501 aatatcctgt ggtgtgattt tgacaagtcg atacccttga agaacctgac tttcaattcc
4561 tcagctgtgt ttacagatat ctgctcctac ccagagtact ttgtcttcac gggggtgttg
4621 gccatggtga cctgtgcagt tttcctccgg ctgaactccg tcctgaagct ggcagtgctg
4681 ctgatcatga ttgccatcta tgccctgctc actgagaccg tctacgcagg cctctttctg
4741 cgttatgaca acctcaacca cagtggagaa gatttcctgg ggaccaagga ggtatcactg
4801 ctactgatgg ccatgttcct cctggctgtg ttctaccatg gacagcagct ggagtacaca
4861 gcccgcctgg acttcctttg gcgagtacag gccaaagagg agatcaatga gatgaaggag
4921 ctgagggaac acaatgagaa catgctccgg aatatcttac ccagccatgt ggcccgccat
4981 ttcctagaga aggaccgaga caatgaggag ctgtattctc aatcctatga tgctgttggg
5041 gtgatgtttg cctccatccc aggatttgcg gacttttact ctcagactga aatgaataac
5101 cagggagtgg aatgcctgcg cttgctcaat gagatcattg ctgacttcga tgagttgctt
5161 ggtgaagacc gatttcaaga cattgaaaag attaagacca ttggcagcac ctacatggcc
5221 gtgtcaggcc tgtcacctga aaaacagcaa tgtgaagaca agtggggaca tttgtgtgct
5281 ctggctgact tctcactcgc cctgacagaa agcatacagg agatcaacaa gcattcattc
5341 aacaattttg aactccggat tggcatcagc cacggctcag tggtagctgg cgttatcggc
5401 gctaagaaac cacagtatga catttggggc aaaactgtga acctggcaag ccgaatggac
5461 agcacggggg ttagtggccg gatccaagtc ccagaggaga cctatctcat cctgaaggac
5521 cagggctttg cctttgatta ccgaggggag atctatgtga agggtatcag tgaacaggaa
5581 ggaaaaatca aaacgtactt tcttctggga agagtccaac ccaacccatt catcttgccc
5641 ccaagaagac tgcctgggca gtactccctg gccgcggttg tcctgggact tgtccagtcc
5701 ctcaataggc aaaggcagaa gcagctactc aatgagaaca acaacacagg aatcatcaag
5761 ggtcattaca accggcggac tttgttgtca cccagcggca cagagcctgg agcccaggct
5821 gaaggcaccg acaaatctga tttgccataa aagcattttc tttctgtttt tttttttttt
5881 tgtatttctt ttatatataa aataaatata ctaataaaaa ggtttaattt tttttagaac
5941 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaacccc aaaaaaaaaa
6001 aaaaa
//