LOCUS Z35284 2065 bp mRNA linear HUM 14-NOV-2006
DEFINITION H.sapiens mRNA for MDR3 P-glycoprotein.
ACCESSION Z35284
VERSION Z35284.1
KEYWORDS MDR3 P-glycoprotein; phospholipid translocator.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2065)
AUTHORS Smit J.J., Mol C.A., van Deemter L., Wagenaar E., Schinkel A.H.,
Borst P.
TITLE Characterization of the promoter region of the human MDR3
P-glycoprotein gene
JOURNAL Biochim. Biophys. Acta 1261(1), 44-56(1995).
PUBMED 7893760
REFERENCE 2 (bases 1 to 2065)
AUTHORS Smit J.J.
JOURNAL Submitted (07-JUL-1994) to the INSDC. Smit J. J., The Netherlands
Cancer Institute, Division of Molecular Biology, 121 Plesmanlaan,
Amsterdam, The Netherlands, 1066 CX
FEATURES Location/Qualifiers
source 1..2065
/db_xref="H-InvDB:HIT000327023"
/organism="Homo sapiens"
/chromosome="7"
/mol_type="mRNA"
/clone="3.11"
/tissue_type="Liver"
/germline
/db_xref="taxon:9606"
mRNA 1..2065
/partial
/citation=[1]
CDS 1850..>2065
/product="MDR3 P-glycoprotein"
/function="putative phospholipid translocator"
/note="this sequence corresponds to part of the MDR3 cDNA
reported in van der Bliek et al. (1988) Gene 71: 401-411"
/db_xref="GOA:P21439"
/db_xref="H-InvDB:HIT000327023.12"
/db_xref="HGNC:HGNC:45"
/db_xref="InterPro:IPR003439"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR011527"
/db_xref="InterPro:IPR017871"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR030275"
/db_xref="InterPro:IPR036640"
/db_xref="InterPro:IPR039421"
/db_xref="UniProtKB/Swiss-Prot:P21439"
/citation=[1]
/citation=[2]
/protein_id="CAA84542.1"
/translation="MDLEAAKNGTAWRPTSAEGDFELGISSKQKRKKTKTVKMIGVLT
LFRYSDWQDKLFMSLGTRGSSRVDLQAC"
BASE COUNT 695 a 331 c 550 g 489 t
ORIGIN
1 atctctatcc ttcttctggt ccttcctaga aaatcaggtg gagatgatag tggcttgcat
61 gatggtggta gagctggagg tgcagggcaa aggtcagatt ctgaatatat tttgaaagta
121 aaggcaacaa gatttcctga cagattgatt atggtgtgtc aaagaaagag aggaatgcag
181 gatgattcca gtgtttttgt tgacaactat aagtctggag ctgccaactg gatgcagaag
241 ttcactggag ggcccagcct ggggaaagga tcaggagcag gttaggcatg ttaagcttga
301 gatgtctgtt aaacatccag ataggaatgt caaagatgca cttgtgttta agagtcagga
361 atgcaagagg gaattttagg ctagaaacaa aaagttagaa attattcgat acagatggta
421 tttaaagctg tgtgactgac tgacatgaca gaagtggcga gaatagactg agaagtccaa
481 ggaatgagcc ttggaccact ccagtgttag gtaagtagtt gaaaaaaaga gagagagaga
541 aggcatcaaa ggagactgag gaagagtgat caggaaagca taggaaaatc cgagaaacat
601 atggtgtcct ggaatctata tgaaaaagat atattcagaa agacagagtg ataaatctgt
661 caaattattg aatttgtcag gtaaaataag aacagagaat tgatctttgg acttagcaaa
721 gcagagatta tcagtgactt ttataaaaat agtttcggta gtgtggaaag atcaaacttc
781 tgtttagagt gggtttcaga gagaacaaca ggaattgaag aagtaataaa ctttgccaac
841 cagtttagct ccaaaggaaa agagggaaat atgatggtag ctggcagggg aagtgtggtc
901 aagagaggtt ttttgtttgt ttttcaagat ggaagaaata acagtatgta tgtaagctca
961 caggagggat ccagcaggca tggggaaatt gatgatatag gacagaaagg gaagaatggc
1021 tccttgtgaa agtgaaaggg gatgggatct acaggatgaa catgcaaaca aagactggct
1081 gcaaagagag gcatgaatag ttcatttaca gaaacagcaa aggcagagtg ttggtacaga
1141 tgctggtaag tggaaaaata tcatggtagg aggttatgga gttccattct aaacacttca
1201 acttcatcag tgaaataagc acggtaattt agcagaatgt gaagatgtaa aagaacagaa
1261 tttgagaaaa cagacgatat gaaataatta ttagaaaagc agagactgaa gaaactgtca
1321 tctccttatg tgctaatgag tttaataatg tcctccagtc accacaagcc ttctttcaaa
1381 ctacacaatt ccaactgctt ccgtctcaga gtatcttgaa ataatgatct gaccgcctgt
1441 tagaccagtg aagggaagga atttgggttg atttaagaag agaatcctca tggtcatggt
1501 agactgatat ggagagaaaa cattttgagg aaaaatactc aactaaattc atttctactc
1561 cagcatgcag tttcaagtca agttccacct tagctccagg tggcaggcag agcaggatgc
1621 agaggcacag cacaagtaag ggatccaatg actgagtcaa gaattacata acctggccag
1681 acagctggta catgggaaag tgctaagagg gcaccaacag cgttcctcct ccccaaggag
1741 cataatgtga tggttcctgc cggccctggc tgactctcgc cgtccttgga gataattggg
1801 ttcagtgcca cctggaccag aactggggat gcggaagcaa gaggctgaga tggatcttga
1861 ggcggcaaag aacggaacag cctggcgccc cacgagcgcg gagggcgact ttgaactggg
1921 catcagcagc aaacaaaaaa ggaaaaaaac gaagacagtg aaaatgattg gagtattaac
1981 attgtttcga tactccgatt ggcaggataa attgtttatg tcgctgggta cccggggatc
2041 ctctagagtc gacctgcagg catgc
//