LOCUS Z33998 2235 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for human lymphoid tyrosine kinase related to murine
Blk.
ACCESSION Z33998
VERSION Z33998.1
KEYWORDS protein tyrosine kinase; protein-tyrosine kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2235)
AUTHORS Islam K.B., Rabbani H., Larsson C., Sanders R., Smith C.I.
TITLE Molecular cloning, characterization, and chromosomal localization
of a human lymphoid tyrosine kinase related to murine Blk
JOURNAL J. Immunol. 154(3), 1265-1272(1995).
PUBMED 7822795
REFERENCE 2 (bases 1 to 2235)
AUTHORS Islam K.B.
JOURNAL Submitted (26-MAY-1994) to the INSDC. Khalid B. Islam, Center for
BioTechnology, NOVUM, Karolinska, Institute, Halsovagen 7,
Huddinge, 141 57, Sweden
FEATURES Location/Qualifiers
source 1..2235
/db_xref="H-InvDB:HIT000326958"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="cDNA library BL-29 of Dr. P. Sideras"
/clone="clone BLK 1A.1"
/cell_line="Burkitt's lymphoma cell line BL-29"
/cell_type="B-lymphocyte"
/germline
/db_xref="taxon:9606"
CDS 223..1740
/standard_name="Human lymphoid protein tyrosine kinase
related to murine BLK"
/product="Protein-Tyrosine Kinase"
/db_xref="GOA:P51451"
/db_xref="H-InvDB:HIT000326958.14"
/db_xref="HGNC:HGNC:1057"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR000980"
/db_xref="InterPro:IPR001245"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR020635"
/db_xref="InterPro:IPR035853"
/db_xref="InterPro:IPR036028"
/db_xref="InterPro:IPR036860"
/db_xref="UniProtKB/Swiss-Prot:P51451"
/protein_id="CAA83965.1"
/translation="MGLVSSKKPDKEKPIKEKDKGQWSPLKVSAQDKDAPPLPPLVVF
NHLTPPPPDEHLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLKGTGDWWLARSLVT
GREGYVPSNFVARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAF
SLSVKDVTTQGELIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTL
PCVRPAPQNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTM
SPEAFLGEANMMKALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSL
PRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQ
EGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLER
GYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTATERQYELQP"
regulatory 2211..2216
/regulatory_class="polyA_signal_sequence"
polyA_site 2231
BASE COUNT 484 a 661 c 674 g 416 t
ORIGIN
1 gggaggctct gatcgcagac cgggggtgct gccacctctg tctgctgccg gcagaaagcc
61 acaagccatg aaaactgatt gagatgagaa gaattcatct gggactggct tttgctttag
121 gatggtgttg gaagttgctc gttgtcgcta ggagcctgct ccactgtaag ggtgtcggga
181 tctgaagagc tatggtgaaa caccactgaa gcattgccaa ggatggggct ggtaagtagc
241 aaaaagccgg acaaggaaaa gccgatcaaa gagaaggaca agggccaatg gagccccctg
301 aaggtcagcg cccaagacaa ggacgccccg ccactgccgc ccctggttgt cttcaaccac
361 cttactcctc caccgcccga tgaacacctg gatgaagaca agcatttcgt ggtggctctg
421 tatgactaca ccgctatgaa tgatcgggac ctgcagatgc tgaaggggga gaagctacag
481 gtcctgaagg gaactggaga ctggtggctg gccaggtcac tcgtcacagg aagagaaggc
541 tatgtgccca gcaactttgt ggcccgagtg gagagcctgg aaatggaaag gtggttcttt
601 agatcacagg gtcggaagga ggctgagagg cagcttcttg ctccaatcaa caaggccggc
661 tcctttctta tcagagagag tgaaaccaac aaaggtgcct tctccctgtc tgtgaaggat
721 gtcaccaccc agggggagct gatcaagcac tataagatcc gctgcctgga tgaagggggc
781 tactacatct ccccccggat caccttcccc tcgctccagg ccctggtgca gcactattct
841 aagaaggggg atggtctatg ccagaggctg accctgccct gtgtgcgccc ggccccgcag
901 aatccctggg cccaggatga atgggagatc ccccggcagt ctctcaggct ggtcaggaaa
961 ctcgggtctg gacaattcgg cgaagtctgg atgggttact acaaaaacaa catgaaggtg
1021 gccattaaga cgctgaagga gggaaccatg tctccagaag ccttcctggg tgaggccaac
1081 atgatgaagg ctctgcagca cgagcggctg gtccgactct acgcagtggt caccaaggag
1141 cccatctaca ttgtcaccga gtacatggcc agaggatgcc tgctggattt cctgaagaca
1201 gatgaaggga gcagattgtc actcccaagg ctgattgaca tgtcggcgca gattgctgaa
1261 gggatggcat acattgagcg catgaattcc atccaccgcg acctgcgggc ggccaacatc
1321 ctggtgtctg aggccttgtg ctgcaaaatt gctgattttg gcttggctcg aatcatcgac
1381 agtgaataca cggcccaaga gggggccaag ttccccatca agtggacagc cccggaagcc
1441 atccacttcg gggtcttcac catcaaagca gacgtgtggt cgtttggagt cctcctgatg
1501 gaagttgtca cttatgggcg ggtgccatac ccagggatga gcaaccccga ggtcatccgc
1561 aacctggagc gcggctaccg catgccgcgc cccgacacct gcccgcccga gctgtaccgc
1621 ggcgtcatcg ccgagtgctg gcgcagccgg cccgaggagc ggcccacctt cgagttcctg
1681 cagtcggtgc tggaggactt ctacacggcc accgagcggc agtacgagct gcagccctag
1741 ccggccgcgc ccgcctgcgc cccgtgccca cctctgcgcg gacgaccccg acttccgtgc
1801 catcccagac gggccgcgaa ggcggggtgt cgcctgtgcc cttttctcag acccggaatc
1861 cagtgggcag aggcagcttc gcagggggtc cccggacgga ctccttcacc gactgcaccc
1921 ccgggcgagt tacgcggcct ctctgtgccg cttcatttgt agagggctgt aacagtgacc
1981 tcgcacggtc atccggagta ctaagcccca gtaaggtgtt caggactggt aagcgactgt
2041 catcaagtaa ggcccccgtg ctgggcaccc cccgtgctgg ccgcgtcccc gcctctgcgc
2101 cctgcgtgga ccccgccctg ccccgctaca gaagccagac tgggtcccgc ggacgccagc
2161 aggggcaacc ccagcctagg ctgcgctcca gcactgcggg gcttttctgc aataaagtca
2221 cgagcgttcg aaaaa
//