LOCUS Z28409 2307 bp mRNA linear HUM 16-JUN-1994
DEFINITION H.sapiens coprox gene for coproporphyrinogen oxidase.
ACCESSION Z28409
VERSION Z28409.1
KEYWORDS coproporphyrinogen oxidase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2307)
AUTHORS Martasek P., Camadro J.M., Delfau-Larue M.H., Dumas J.B.,
Montagne J.J., de Verneuil H., Labbe P., Grandchamp B.
TITLE Molecular cloning, sequencing, and functional expression of a cDNA
encoding human coproporphyrinogen oxidase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 91(8), 3024-3028(1994).
PUBMED 8159699
REFERENCE 2 (bases 1 to 2307)
AUTHORS Grandchamp B.
JOURNAL Submitted (03-DEC-1993) to the INSDC. Grandchamp B., Faculte Xavier
Bichat Genetique Moleculaire 16 Rue Huchard Paris FRANCE 75018
FEATURES Location/Qualifiers
source 1..2307
/db_xref="H-InvDB:HIT000326841"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_type="fibroblast"
/tissue_type="foreskin"
/db_xref="taxon:9606"
mRNA <1..2307
/gene="coprox"
/standard_name="coproporphyrinogen oxidase"
CDS <1..1065
/codon_start=1
/product="coproporphyrinogen oxidase"
/function="enzyme"
/EC_number="1.3.3.3"
/db_xref="GOA:P36551"
/db_xref="H-InvDB:HIT000326841.13"
/db_xref="HGNC:HGNC:2321"
/db_xref="InterPro:IPR001260"
/db_xref="InterPro:IPR018375"
/db_xref="InterPro:IPR036406"
/db_xref="PDB:2AEX"
/db_xref="UniProtKB/Swiss-Prot:P36551"
/protein_id="CAA82250.1"
/translation="MLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRR
PGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEK
AGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVTHPKNPHAPTIHFN
YRYFEVEEADGHKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKW
CDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDS
FTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPS
ENSKEAEILEVLRHPRDWVR"
prim_transcript 1..2307
mat_peptide 31..1065
/product="coproporphyrinogen oxidase"
/EC_number="1.3.3.3"
regulatory 2277..2282
/regulatory_class="polyA_signal_sequence"
BASE COUNT 629 a 419 c 536 g 723 t
ORIGIN
1 atgttgccta agacctcggg gacgcgggcc acttcgctgg ggaggccgga ggaggaggag
61 gatgagctgg cccaccgctg cagcagcttc atggccccgc ctgtgaccga cctgggcgag
121 ctgcgaagga ggccgggcga catgaagacc aagatggagc tgctgattct ggagacccag
181 gcccaggtgt gccaggctct ggcacaggta gacgggggcg ccaacttttc tgtggaccgg
241 tgggagagga aggaaggagg tggcggcatc agctgtgtac ttcaagatgg gtgtgttttc
301 gaaaaggctg gggtgagcat ttctgttgtt catggaaatc tttcagagga agctgcaaaa
361 caaatgagaa gcagaggaaa agttctgaag actaaagatg gtaaattgcc attttgtgct
421 atgggcgtga gctctgttac ccaccccaag aatcctcatg ctcctactat ccatttcaac
481 tacagatact ttgaagtaga agaagctgat ggccacaagc agtggtggtt tggtggtgga
541 tgtgacctca ctccaacata cttgaatcaa gaagacgctg tccattttca cagaactctg
601 aaggaggctt gtgaccagca tggtccagat ctctacccca aatttaaaaa atggtgtgat
661 gattacttct ttatagccca tcgtggagag cggcggggca ttggtggtat cttttttgat
721 gatcttgact ctccgtccaa ggaggaggtg tttcgctttg tacagagctg tgccagggct
781 gtagttcctt cttacattcc ccttgtgaaa aagcactgtg atgactcatt caccccccag
841 gagaagctgt ggcagcagct cagaagagga cggtatgtag aatttaatct gctgtatgat
901 cggggcacaa agtttggcct cttcactcca ggatccagaa ttgaaagtat cttgatgtct
961 ttacctctaa ctgcccgatg ggagtacatg cattcaccct cagagaattc caaagaagct
1021 gaaattctgg aagttctacg ccatccaagg gactgggtgc gttgatgcag gcagaatggc
1081 tgtgcagggg tttggagggc acacgatgtg tgctccccca tgccactggc actttgccac
1141 tgtgtggcag ttacccgtgc cttagtcttc tccactctgc accctacctc gtgggcagat
1201 gataacatgt tttggatgct gtcagtgatg aatggtggga tggccagatt gtcagagtca
1261 attgattaaa cctcatttat acttctagtg tcattttata tgactagttt acaaaatagg
1321 acattgagtt tccaagtatt gagataaggg aatataaata gtattatatg tatcaggaaa
1381 tctctcatct tgtttttgtt tcatgtattt tttaaagttt tcatttgtgc cacaaaaatc
1441 tgtcgtggaa tatattttat tttcattaat tcagtgaagt tgagacttca tagtaatttt
1501 agaatgcaac ttgaaggtaa aaattttact ttgtcaatac tgaagtctct gctgtaatcc
1561 ttatatatct tctccagaga acataatatt gtcaaataga tacacatttt tctaataggt
1621 atttagaagc acttgaaata ttcttaatct ctgcatgtgt tacaattcag ttatttctgt
1681 cgtttgtaaa ctctaaagtg acattactat tattttagag atgtctaagt tgtaattttg
1741 atttttgtgg aaccattgtt tgttaatgtt gggatttctg cacttttgaa tgtgaaagct
1801 tatatccctg aattctgata cttaagagtt ttctatttct gacatctctg tgtggaagtt
1861 gagactaaga ataatcctag ggatgtcatg aatttaggca atgtttctca tttggaaaat
1921 gaaatgagaa ataatttcct tctttaaagc aagtatatat agtatgagaa acttggaggc
1981 atttcataca cacgtttctt aggaaaatgg acacattgaa aatgtcctct tttttatatt
2041 agagattctg cagctctttg ctcttaagag caaatcacaa caggattctt aatgtatgat
2101 ttctttgttc atatattatg aatgtattat tttatttgct tcgtaataaa gtttataaga
2161 aagagcatct catacatatc attatcgtgg aacacgttga atgtttgtga ttctgtgtgg
2221 cctttttggg gctggaaaat gtatgaattc ttcaactgtc ttacaagaga tctgctaata
2281 aattttatta ttaaataaga aaaaaaa
//