LOCUS Z23022 3013 bp mRNA linear HUM 14-NOV-2006
DEFINITION H.sapiens of BCL1 mRNA encoding cyclin.
ACCESSION Z23022
VERSION Z23022.1
KEYWORDS cyclin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3013)
AUTHORS Rimokh R., Berger F., Bastard C., Klein B., French M.,
Archimbaud E., Rouault J.P., Santa Lucia B., Duret L., Vuillaume M.
TITLE Rearrangement of CCND1 (BCL1/PRAD1) 3' untranslated region in
mantle-cell lymphomas and t(11q13)-associated leukemias
JOURNAL Blood 83(12), 3689-3696(1994).
PUBMED 8204893
REFERENCE 2 (bases 2276 to 3013)
AUTHORS Kaplan D.J., Jurka J., Solus J.F., Duncan C.H.
TITLE Medium reiteration frequency repetitive sequences in the human
genome
JOURNAL Nucleic Acids Res. 19(17), 4731-4738(1991).
PUBMED 1891362
REFERENCE 3 (bases 1 to 2275)
AUTHORS Motokura T., Bloom T., Jueppner H., Ruderman J., Kronenberg H.,
Arnold A.
TITLE A novel cyclin encoded by a bcl1-linked candidate oncogene
JOURNAL Nature 350(6318), 512-515(1991).
PUBMED 1826542
REFERENCE 4 (bases 1 to 3013)
AUTHORS Rimokh R.
JOURNAL Submitted (16-JUN-1993) to the INSDC. Ruth Rimokh, Laboratoire de
Cytogenetique Moleculaire, Hopital, Edouard Herriot, Pavillon E,
Place d'Arsonval, Lyon, 69437, FRANCE
FEATURES Location/Qualifiers
source 1..3013
/organism="Homo sapiens"
/chromosome="11q13.3"
/mol_type="mRNA"
/cell_type="tumoral lymphoid Bcell t(11:19)(q13:q13)
translocation"
/db_xref="taxon:9606"
CDS 147..1034
/gene="BCL1"
/standard_name="PRAD1/BCL1 cyclin gene"
/product="cyclin"
/db_xref="GOA:P24385"
/db_xref="HGNC:HGNC:1582"
/db_xref="InterPro:IPR004367"
/db_xref="InterPro:IPR006671"
/db_xref="InterPro:IPR013763"
/db_xref="InterPro:IPR015451"
/db_xref="InterPro:IPR036915"
/db_xref="InterPro:IPR039361"
/db_xref="PDB:2W96"
/db_xref="PDB:2W99"
/db_xref="PDB:2W9F"
/db_xref="PDB:2W9Z"
/db_xref="PDB:5VZU"
/db_xref="UniProtKB/Swiss-Prot:P24385"
/protein_id="CAA80558.1"
/translation="MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSY
FKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLL
GATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDF
IEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLR
SPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEE
EEEEVDLACTPTDVRDVDI"
misc_difference 870
/replace="a"
/note="conflict"
/citation=[3]
misc_difference 1100
/replace="a"
/note="conflict"
/citation=[3]
repeat_region 2276..3013
/rpt_family="MER11"
/citation=[2]
BASE COUNT 783 a 741 c 771 g 718 t
ORIGIN
1 gcgcagtagc agcgagcagc agagtccgca cgctccggcg aggggcagaa gagcgcgagg
61 gagcgcgggg cagcagaagc gagagccgag cgcggaccca gccaggaccc acagccctcc
121 ccagctgccc aggaagagcc ccagccatgg aacaccagct cctgtgctgc gaagtggaaa
181 ccatccgccg cgcgtacccc gatgccaacc tcctcaacga ccgggtgctg cgggccatgc
241 tgaaggcgga ggagacctgc gcgccctcgg tgtcctactt caaatgtgtg cagaaggagg
301 tcctgccgtc catgcggaag atcgtcgcca cctggatgct ggaggtctgc gaggaacaga
361 agtgcgagga ggaggtcttc ccgctggcca tgaactacct ggaccgcttc ctgtcgctgg
421 agcccgtgaa aaagagccgc ctgcagctgc tgggggccac ttgcatgttc gtggcctcta
481 agatgaagga gaccatcccc ctgacggccg agaagctgtg catctacacc gacaactcca
541 tccggcccga ggagctgctg caaatggagc tgctcctggt gaacaagctc aagtggaacc
601 tggccgcaat gaccccgcac gatttcattg aacacttcct ctccaaaatg ccagaggcgg
661 aggagaacaa acagatcatc cgcaaacacg cgcagacctt cgttgccctc tgtgccacag
721 atgtgaagtt catttccaat ccgccctcca tggtggcagc ggggagcgtg gtggccgcag
781 tgcaaggcct gaacctgagg agccccaaca acttcctgtc ctactaccgc ctcacacgct
841 tcctctccag agtgatcaag tgtgacccgg actgcctccg ggcctgccag gagcagatcg
901 aagccctgct ggagtcaagc ctgcgccagg cccagcagaa catggacccc aaggccgccg
961 aggaggagga agaggaggag gaggaggtgg acctggcttg cacacccacc gacgtgcggg
1021 acgtggacat ctgagggcgc caggcaggcg ggcgccaccg ccacccgcag cgagggcgga
1081 gccggcccca ggtgctcccc tgacagtccc tcctctccgg agcattttga taccagaagg
1141 gaaagcttca ttctccttgt tgttggttgt tttttccttt gctctttccc ccttccatct
1201 ctgacttaag caaaagaaaa agattaccca aaaactgtct ttaaaagaga gagagagaaa
1261 aaaaaaatag tatttgcata accctgagcg gtgggggagg agggttgtgc tacagatgat
1321 agaggatttt ataccccaat aatcaactcg tttttatatt aatgtacttg tttctctgtt
1381 gtaagaatag gcattaacac aaaggaggcg tctcgggaga ggattaggtt ccatccttta
1441 cgtgtttaaa aaaaagcata aaaacatttt aaaaacatag aaaaattcag caaaccattt
1501 ttaaagtaga agagggtttt aggtagaaaa acatattctt gtgcttttcc tgataaagca
1561 cagctgtagt ggggttctag gcatctctgt actttgcttg ctcatatgca tgtagtcact
1621 ttataagtca ttgtatgtta ttatattccg taggtagatg tgtaacctct tcaccttatt
1681 catggctgaa gtcacctctt ggttacagta gcgtagcgtg gccgtgtgca tgtcctttgc
1741 gcctgtgacc accaccccaa caaaccatcc agtgacaaac catccagtgg aggtttgtcg
1801 ggcaccagcc agcgtagcag ggtcgggaaa ggccacctgt cccactccta cgatacgcta
1861 ctataaagag aagacgaaat agtgacataa tatattctat ttttatactc ttcctatttt
1921 tgtagtgacc tgtttatgag atgctggttt tctacccaac ggccctgcag ccagctcacg
1981 tccaggttca acccacagct acttggtttg tgttcttctt catattctaa aaccattcca
2041 tttccaagca ctttcagtcc aataggtgta ggaaatagcg ctgtttttgt tgtgtgtgca
2101 gggagggcag ttttctaatg gaatggtttg ggaatatcca tgtacttgtt tgcaagcagg
2161 actttgaggc aagtgtgggc cactgtggtg gcagtggagg tggggtgttt gggaggctgc
2221 gtgccagtca agaagaaaaa ggtttgcatt ctcacattgc caggatgata agttcaactg
2281 agccttaaac cagcaagttt tttattaagg gtttcaagag gggagggggt gtgagaacat
2341 ggagtagagc tcatgcttca aagggcaaaa aacagaacaa agatcacttg cttctgaggg
2401 aacaggagaa aaggcaacac agaactactg ataagggtcc atgttcagcg gtgcacgtat
2461 tatcttgata aacatcttga acaaaaaata gggaaacgtc tgaccacaaa ttcaccaggg
2521 tggagttttt ccccaccgta gtaagcctga gggtactgca ggagatcagg gcgtatctca
2581 gtccttatct caaccacgta agacagacat tcccagagca gctgtttata gacctctccc
2641 caggaatgca ttcctttccc agggtattaa tattaatatt gcttgctagg aaaagaattt
2701 agcgatatcc tccctacttg catgtccttt tataggctct ctgcaagaag aaaaatatgg
2761 ctttttttgc ctgaccctgc aggcagtcag accttatggt tgtcttccct tgttccctaa
2821 aatcgctgtt attctgtttt ttctcaaggt gcactgattt catattgttc aaacacacgt
2881 tttacaatca atttgtacag ttaacacaat tatcacggtg gtcctgaggt gacatacatc
2941 ctcagcttac gaagataaca ggattaagag atgagagtaa gacaggcgta agaaattata
3001 aaagtattaa ttt
//