LOCUS Z21876 2750 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens X-linked ALD gene.
ACCESSION Z21876 S56163
VERSION Z21876.1
KEYWORDS ADL gene; ALD protein (ALDP); X-linked.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2750)
AUTHORS Mosser J., Douar A.M., Sarde C.O., Kioschis P., Feil R., Moser H.,
Poustka A., Mandel J.L., Aubourg P.
TITLE Putative X-linked adrenoleukodystrophy gene shares unexpected
homology with ABC transporters
JOURNAL Nature 361(6414), 726-730(1993).
PUBMED 8441467
REFERENCE 2 (bases 1 to 2750)
AUTHORS Sarde C.O.
JOURNAL Submitted (03-MAR-1993) to the INSDC. C O Sarde, Genetique Humaine,
INSERM U184-LGME CNRS, Institut de Chimie Biologique, 11, Rue
Humann, Strasbourg, 67085, France
FEATURES Location/Qualifiers
source 1..2750
/db_xref="H-InvDB:HIT000326621"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="Hela random-primed cDNA library"
/clone="H7"
/db_xref="taxon:9606"
mRNA 1..2750
/gene="X-linked ALD"
CDS 387..2624
/product="ALD protein (ALDP)"
/db_xref="GOA:P33897"
/db_xref="H-InvDB:HIT000326621.13"
/db_xref="HGNC:HGNC:61"
/db_xref="InterPro:IPR003439"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR005283"
/db_xref="InterPro:IPR011527"
/db_xref="InterPro:IPR017871"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR031237"
/db_xref="InterPro:IPR036640"
/db_xref="UniProtKB/Swiss-Prot:P33897"
/protein_id="CAA79922.1"
/translation="MPVLSRPRPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPAR
GLQAPAGEPTQEASGVAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALV
SRTFLSVYVARLDGRLARCIARKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLAL
SFRSRLVAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKP
LLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRK
GELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFL
MKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLL
TAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTI
GRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGP
NGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDM
QRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPK
YALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFE
KLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGL
QGAST"
BASE COUNT 491 a 919 c 885 g 455 t
ORIGIN
1 gcggacggac gcgcctggtg ccccggggag gggcgccacc gggggaggag gaggaggaga
61 aggtggagag gaagagacgc cccctctgcc cgagacctct caaggccctg acctcagggg
121 ccagggcact gacaggacag gagagccaag ttcctccact tgggctgccc gaagaggccg
181 cgaccctgga gggccctgag cccaccgcac caggggcccc agcaccaccc cgggggccta
241 aagcgacagt ctcaggggcc atcgcaaggt ttccagttgc ctagacaaca ggcccagggt
301 cagagcaaca atccttccag ccacctgcct caactgctgc cccaggcacc agccccagtc
361 cctacgcggc agccagccca ggtgacatgc cggtgctctc caggccccgg ccctggcggg
421 ggaacacgct gaagcgcacg gccgtgctcc tggccctcgc ggcctatgga gcccacaaag
481 tctacccctt ggtgcgccag tgcctggccc cggccagggg tcttcaggcg cccgccgggg
541 agcccacgca ggaggcctcc ggggtcgcgg cggccaaagc tggcatgaac cgggtattcc
601 tgcagcggct cctgtggctc ctgcggctgc tgttcccccg ggtcctgtgc cgggagacgg
661 ggctgctggc cctgcactcg gccgccttgg tgagccgcac cttcctgtcg gtgtatgtgg
721 cccgcctgga cggaaggctg gcccgctgca tcgcccgcaa ggacccgcgg gcttttggct
781 ggcagctgct gcagtggctc ctcatcgccc tccctgctac cttcgtcaac agtgccatcc
841 gttacctgga gggccaactg gccctgtcgt tccgcagccg tctggtggcc cacgcctacc
901 gcctctactt ctcccagcag acctactacc gggtcagcaa catggacggg cggcttcgca
961 accctgacca gtctctgacg gaggacgtgg tggcctttgc ggcctctgtg gcccacctct
1021 actccaacct gaccaagcca ctcctggacg tggctgtgac ttcctacacc ctgcttcggg
1081 cggcccgctc ccgtggagcc ggcacagcct ggccctcggc catcgccggc ctcgtggtgt
1141 tcctcacggc caacgtgctg cgggccttct cgcccaagtt cggggagctg gtggcagagg
1201 aggcgcggcg gaagggggag ctgcgctaca tgcactcgcg tgtggtggcc aactcggagg
1261 agatcgcctt ctatgggggc catgaggtgg agctggccct gctacagcgc tcctaccagg
1321 acctggcctc gcagatcaac ctcatccttc tggaacgcct gtggtatgtt atgctggagc
1381 agttcctcat gaagtatgtg tggagcgcct cgggcctgct catggtggct gtccccatca
1441 tcactgccac tggctactca gagtcagatg cagaggccgt gaagaaggca gccttggaaa
1501 agaaggagga ggagctggtg agcgagcgca cagaagcctt cactattgcc cgcaacctcc
1561 tgacagcggc tgcagatgcc attgagcgga tcatgtcgtc gtacaaggag gtgacggagc
1621 tggctggcta cacagcccgg gtgcacgaga tgttccaggt atttgaagat gttcagcgct
1681 gtcacttcaa gaggcccagg gagctagagg acgctcaggc ggggtctggg accataggcc
1741 ggtctggtgt ccgtgtggag ggccccctga agatccgagg ccaggtggtg gatgtggaac
1801 aggggatcat ctgcgagaac atccccatcg tcacgccctc aggagaggtg gtggtggcca
1861 gcctcaacat cagggtggag gaaggcatgc atctgctcat cacaggcccc aatggctgcg
1921 gcaagagctc cctgttccgg atcctgggtg ggctctggcc cacgtacggt ggtgtgctct
1981 acaagccccc accccagcgc atgttctaca tcccgcagag gccctacatg tctgtgggct
2041 ccctgcgtga ccaggtgatc tacccggact cagtggagga catgcaaagg aagggctact
2101 cggagcagga cctggaagcc atcctggacg tcgtgcacct gcaccacatc ctgcagcggg
2161 agggaggttg ggaggctatg tgtgactgga aggacgtcct gtcgggtggc gagaagcaga
2221 gaatcggcat ggcccgcatg ttctaccaca ggcccaagta cgccctcctg gatgaatgca
2281 ccagcgccgt gagcatcgac gtggaaggca agatcttcca ggcggccaag gacgcgggca
2341 ttgccctgct ctccatcacc caccggccct ccctgtggaa ataccacaca cacttgctac
2401 agttcgatgg ggagggcggc tggaagttcg agaagctgga ctcagctgcc cgcctgagcc
2461 tgacggagga gaagcagcgg ctggagcagc agctggcggg cattcccaag atgcagcggc
2521 gcctccagga gctctgccag atcctgggcg aggccgtggc cccagcgcat gtgccggcac
2581 ctagcccgca aggccctggt ggcctccagg gtgcctccac ctgacacaac cgtccccggc
2641 ccctgccccg cccccaagct cggatcacat gaaggagaca gcagcaccca cccatgcacg
2701 caccccgccc ctgcatgcct ggcccctcct cctagaaaac ccttcccgcc
//