LOCUS Z19002 2197 bp mRNA linear HUM 09-SEP-2004
DEFINITION H.sapiens of PLZF gene encoding kruppel-like zinc finger protein.
ACCESSION Z19002
VERSION Z19002.1
KEYWORDS kruppel-like zinc finger protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2197)
AUTHORS Chen Z., Brand N.J., Chen A., Chen S.J., Tong J.H., Wang Z.Y.,
Waxman S., Zelent A.Z.
TITLE Fusion between a novel Kruppel-like zinc finger gene and the
retinoic acid receptor-alpha locus due to a variant t(11;17)
translocation associated with acute promyelocytic leukaemia
JOURNAL EMBO J. 12(3), 1161-1167(1993).
PUBMED 8384553
REFERENCE 2 (bases 1 to 2197)
AUTHORS Zelent A.Z.
JOURNAL Submitted (09-DEC-1992) to the INSDC. Zelent A. Z., Institute of
Cancer Research, Leukaemia Research Fund Centre, Fulham Road,
London, United Kingdom, SW3 6JB
FEATURES Location/Qualifiers
source 1..2197
/db_xref="H-InvDB:HIT000326606"
/organism="Homo sapiens"
/chromosome="11q23.1"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="human ventricular cDNA lambda ZapII library"
/clone="PLZF"
/tissue_type="heart"
/germline
/db_xref="taxon:9606"
5'UTR 1..75
CDS 76..2097
/gene="PLZF"
/product="kruppel-like zinc finger protein"
/function="transcription factor"
/db_xref="GOA:Q05516"
/db_xref="H-InvDB:HIT000326606.13"
/db_xref="HGNC:HGNC:12930"
/db_xref="InterPro:IPR000210"
/db_xref="InterPro:IPR011333"
/db_xref="InterPro:IPR013087"
/db_xref="InterPro:IPR036236"
/db_xref="PDB:1BUO"
/db_xref="PDB:1CS3"
/db_xref="UniProtKB/Swiss-Prot:Q05516"
/protein_id="CAA79489.1"
/translation="MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQE
FHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDL
LYAAEILEIEYLEEQCLKMLETIQASDDNDTEATMADGGAEEEEDRKARYLKNIFISK
HSSEESGYASVAGQSLPGPMVDQSPSVSTSFGLSAMSPTKAAVDSLMTIGQSLLQGTL
QPPAGPEEPTLAGGGRHPGVAEVKTEMMQVDEVPSQDSPGAAESSISGGMGDKVEERG
KEGPGTPTRSSVITSARELHYGREESAEQVPPPAEAGQAPTGRPEHPAPPPEKHLGIY
SVLPNHKADAVLSMPSSVTSGLHVQPALAVSMDFSTYGGLLPQGFIQRELFSKLGELA
VGMKSESRTIGEQCSVCGVELPDNEAVEQHRKLHSGMKTYGCELCGKRFLDSLRLRMH
LLAHSAGAKAFVCDQCGAQFSKEDALETHRQTHTGTDMAVFCLLCGKRFQAQSALQQH
MEVHAGVRSYICSECNRTFPSHTALKRHLRSHTGDHPYECEFCGSCFRDESTLKSHKR
IHTGEKPYECNGCDKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTH
NGASPYQCTICTEYCPSLSSMQKHMKGHKPEEIPPDWRIEKTYLYLCYV"
3'UTR 2098..2197
BASE COUNT 518 a 628 c 683 g 368 t
ORIGIN
1 caggaagccc acccagcccc gccacgcaga gcccagaagg aaagaaagcc tcatgcctga
61 gccgagggga gcaccatgga tctgacaaaa atgggcatga tccagctgca gaaccctagc
121 caccccacgg ggctactgtg caaggccaac cagatgcggc tggccgggac tttgtgcgat
181 gtggtcatca tggtggacag ccaggagttc cacgcccacc ggacggtgct ggcctgcacc
241 agcaagatgt ttgagatcct cttccaccgc aatagtcaac actatacttt ggacttcctc
301 tcgccaaaga ccttccagca gattctggag tatgcatata cagccacgct gcaagccaag
361 gcggaggacc tggatgacct gctgtatgcg gccgagatcc tggagatcga gtacctggag
421 gaacagtgcc tgaagatgct ggagaccatc caggcctcag acgacaatga cacggaggcc
481 accatggccg atggcggggc cgaggaagaa gaggaccgca aggctcggta cctcaagaac
541 atcttcatct cgaagcattc cagcgaggag agtgggtatg ccagtgtggc tggacagagc
601 ctccctgggc ccatggtgga ccagagccct tcagtctcca cttcatttgg tctttcagcc
661 atgagtccca ccaaggctgc agtggacagt ttgatgacca taggacagtc tctcctgcag
721 ggaactcttc agccacctgc agggcccgag gagccaactc tggctggggg tgggcggcac
781 cctggggtgg ctgaggtgaa gacggagatg atgcaggtgg atgaggtgcc cagccaggac
841 agccctgggg cagccgagtc cagcatctca ggagggatgg gggacaaggt tgaggaaaga
901 ggcaaagagg ggcctgggac cccgactcga agcagcgtca tcaccagtgc tagggagcta
961 cactatgggc gagaggagag tgccgagcag gtgccacccc cagctgaggc tggccaggcc
1021 cccactggcc gacctgagca cccagcaccc ccgcctgaga agcatctggg catctactcc
1081 gtgttgccca accacaaggc tgacgctgta ttgagcatgc cgtcttccgt gacctctggc
1141 ctccacgtgc agcctgccct ggctgtctcc atggacttca gcacctatgg ggggctgctg
1201 ccccagggct tcatccagag ggagctgttc agcaagctgg gggagctggc tgtgggcatg
1261 aagtcagaga gccggaccat cggagagcag tgcagcgtgt gtggggtcga gcttcctgat
1321 aacgaggctg tggagcagca caggaagctg cacagtggga tgaagacgta cgggtgcgag
1381 ctctgcggga agcggttcct ggatagtttg cggctgagaa tgcacttact ggctcattca
1441 gcgggtgcca aagcctttgt ctgtgatcag tgcggtgcac agttttcgaa ggaggatgcc
1501 ctggagacac acaggcagac ccatactggc actgacatgg ccgtcttctg tctgctgtgt
1561 gggaagcgct tccaggcgca gagcgcactg cagcagcaca tggaggtcca cgcgggcgtg
1621 cgcagctaca tctgcagtga gtgcaaccgc accttcccca gccacacggc tctcaaacgc
1681 cacctgcgct cacatacagg cgaccacccc tacgagtgtg agttctgtgg cagctgcttc
1741 cgggatgaga gcacactcaa gagccacaaa cgcatccaca cgggtgagaa accctacgag
1801 tgcaatggct gtgacaagaa gttcagcctc aagcatcagc tggagacgca ctatagggtg
1861 cacacaggtg agaagccctt tgagtgtaag ctctgccacc agcgctcccg ggactactcg
1921 gccatgatca agcacctgag aacgcacaac ggcgcctcgc cctaccagtg caccatctgc
1981 acagagtact gccccagcct ctcctccatg cagaagcaca tgaagggcca caagcccgag
2041 gagatcccgc ccgactggag gatagagaag acgtacctct acctgtgcta tgtgtgaagg
2101 gaggcccgcg gcggtggagc cgagcgggga gccaggaaag aagagttgga gtgagatgaa
2161 ggaaggacta tgacaaataa aaaaaaaaaa ggaattc
//