LOCUS Z17227 1875 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for transmebrane receptor protein.
ACCESSION Z17227
VERSION Z17227.1
KEYWORDS CRF2-4; CRFB4; cytokine receptor; transmembrane receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1875)
AUTHORS Lutfalla G., Gardiner K., Uze G.
TITLE A new member of the cytokine receptor gene family maps on
chromosome 21 at less than 35 kb from IFNAR
JOURNAL Genomics 16(2), 366-373(1993).
PUBMED 8314576
REFERENCE 2 (bases 1 to 1875)
AUTHORS Lutfalla G.
JOURNAL Submitted (12-OCT-1992) to the INSDC. Georges LUTFALLA, CNRS, 7 rue
Guy Moquet, Villejuif, 94801, France
FEATURES Location/Qualifiers
source 1..1875
/db_xref="H-InvDB:HIT000326543"
/organism="Homo sapiens"
/chromosome="21"
/strain="Daudi cell line"
/mol_type="mRNA"
/dev_stage="Adult"
/cell_line="Daudi cell line"
/cell_type="B-lymphocyte"
/tissue_type="Lymphoid tumor"
/germline
/db_xref="taxon:9606"
CDS 44..1021
/product="transmembrane receptor precusor"
/db_xref="GOA:Q08334"
/db_xref="H-InvDB:HIT000326543.15"
/db_xref="HGNC:HGNC:5965"
/db_xref="InterPro:IPR003961"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR015373"
/db_xref="InterPro:IPR036116"
/db_xref="PDB:3LQM"
/db_xref="PDB:5T5W"
/db_xref="UniProtKB/Swiss-Prot:Q08334"
/protein_id="CAA78933.1"
/translation="MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPA
FAKGNLTFTAQYLSYRIFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVN
ITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWK
NGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETV
PSWMVAVILMASVFMVCLALLGCFSLLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHN
TLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQS"
sig_peptide 44..100
/product="leader peptide"
mat_peptide 101..1018
/product="transmembrane receptor"
misc_feature 101..703
/product="D200 extracellular domain (cytokine receptors)"
misc_feature 704..790
/product="transmembrane region"
misc_feature 791..1018
/product="intracellular domain"
repeat_region 1329..1653
/rpt_family="Alu"
regulatory 1853..1858
/regulatory_class="polyA_signal_sequence"
polyA_site 1875
BASE COUNT 517 a 425 c 451 g 482 t
ORIGIN
1 gtcgtgtgct tggaggaagc cgcggaaccc ccagcgtccg tccatggcgt ggagccttgg
61 gagctggctg ggtggctgcc tgctggtgtc agcattggga atggtaccac ctcccgaaaa
121 tgtcagaatg aattctgtta atttcaagaa cattctacag tgggagtcac ctgcttttgc
181 caaagggaac ctgactttca cagctcagta cctaagttat aggatattcc aagataaatg
241 catgaatact accttgacgg aatgtgattt ctcaagtctt tccaagtatg gtgaccacac
301 cttgagagtc agggctgaat ttgcagatga gcattcagac tgggtaaaca tcaccttctg
361 tcctgtggat gacaccatta ttggaccccc tggaatgcaa gtagaagtac ttgctgattc
421 tttacatatg cgtttcttag cccctaaaat tgagaatgaa tacgaaactt ggactatgaa
481 gaatgtgtat aactcatgga cttataatgt gcaatactgg aaaaacggta ctgatgaaaa
541 gtttcaaatt actccccagt atgactttga ggtcctcaga aacctggagc catggacaac
601 ttattgtgtt caagttcgag ggtttcttcc tgatcggaac aaagctgggg aatggagtga
661 gcctgtctgt gagcaaacaa cccatgacga aacggtcccc tcctggatgg tggccgtcat
721 cctcatggcc tcggtcttca tggtctgcct ggcactcctc ggctgcttct ccttgctgtg
781 gtgcgtttac aagaagacaa agtacgcctt ctcccctagg aattctcttc cacagcacct
841 gaaagagttt ttgggccatc ctcatcataa cacacttctg tttttctcct ttccattgtc
901 ggatgagaat gatgtttttg acaagctaag tgtcattgca gaagactctg agagcggcaa
961 gcagaatcct ggtgacagct gcagcctcgg gaccccgcct gggcaggggc cccaaagcta
1021 ggctctgaga aggaaacaca ctcggctggg cacagtgacg tactccatct cacatctgcc
1081 tcagtgaggg atcagggcag caaacaaggg ccaagaccat ctgagccagc cccacatcta
1141 gaactccaga cctggactta gccaccagag agctacattt taaaggctgt cttggcaaaa
1201 atactccatt tgggaactca ctgccttata aaggctttca tgatgttttc agaagttggc
1261 cactgagagt gtaattttca gccttttata tcactaaaat aagatcatgt tttaattgtg
1321 agaaacaggg ccgagcacag tggctcacgc ctgtaatacc agcaccttag aggtcgaggc
1381 aggcggatca cttgaggtca ggagttcaag accagcctgg ccaatatggt gaaacccagt
1441 ctctactaaa aatacaaaaa ttagctaggc atgatggcgc atgcctataa tcccagctac
1501 tcgagtgcct gaggcaggag aattgcatga acccgggagg aggaggagga ggttgcagtg
1561 agccgagata gcggcactgc actccagcct gggtgacaaa gtgagactcc atctcaaaaa
1621 aaaaaaaaaa aaattgtgag aaacagaaat acttaaaatg aggaataaga atggagatgt
1681 tacatctggt agatgtaaca ttctaccaga ttatggatgg actgatctga aaatcgacct
1741 caactcaagg gtggtcagct caatgctaca cagagcacgg acttttggat tctttgcagt
1801 actttgaatt tatttttcta cctatatatg ttttatatgc tgctggtgct ccattaaagt
1861 tttactctgt gttgc
//