LOCUS Z13009 4778 bp mRNA linear HUM 01-JUL-1999
DEFINITION H.sapiens mRNA for E-cadherin.
ACCESSION Z13009
VERSION Z13009.1
KEYWORDS E-cadherin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4778)
AUTHORS Bussemakers M.J., van Bokhoven A., Mees S.G., Kemler R.,
Schalken J.A.
TITLE Molecular cloning and characterization of the human E-cadherin cDNA
JOURNAL Mol. Biol. Rep. 17(2), 123-128(1993).
PUBMED 8459805
REFERENCE 2 (bases 1 to 4778)
AUTHORS Bussemakers M.
JOURNAL Submitted (22-JUN-1992) to the INSDC. Bussemakers M., University
Hospital Nijmegen, Geert Grooteplein 16, Nijmegen, The Netherlands.
REFERENCE 3 (bases 1 to 4778)
AUTHORS Bussemakers M.J.G., Giroldi L.A., van Bokhoven A., Schalken J.A.
TITLE Transcriptional regulation of the human E-cadherin gene in human
prostate cancer cell lines: characterization of the human
E-cadherin gene promoter
JOURNAL Biochem. Biophys. Res. Commun. 203(2), 1284-1290(1994).
PUBMED 8093045
FEATURES Location/Qualifiers
source 1..4778
/db_xref="H-InvDB:HIT000326429"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..4778
CDS 95..2743
/product="E-cadherin"
/db_xref="GOA:P12830"
/db_xref="H-InvDB:HIT000326429.15"
/db_xref="HGNC:HGNC:1748"
/db_xref="InterPro:IPR000233"
/db_xref="InterPro:IPR002126"
/db_xref="InterPro:IPR014868"
/db_xref="InterPro:IPR015919"
/db_xref="InterPro:IPR020894"
/db_xref="InterPro:IPR027397"
/db_xref="InterPro:IPR039808"
/db_xref="PDB:1O6S"
/db_xref="PDB:2O72"
/db_xref="PDB:2OMT"
/db_xref="PDB:2OMU"
/db_xref="PDB:2OMV"
/db_xref="PDB:2OMX"
/db_xref="PDB:2OMY"
/db_xref="PDB:2OMZ"
/db_xref="PDB:3FF7"
/db_xref="PDB:3FF8"
/db_xref="PDB:3L6X"
/db_xref="PDB:3L6Y"
/db_xref="PDB:4ZT1"
/db_xref="PDB:4ZTE"
/db_xref="PDB:6CXY"
/db_xref="PDB:6OLE"
/db_xref="PDB:6OLF"
/db_xref="PDB:6OLG"
/db_xref="UniProtKB/Swiss-Prot:P12830"
/protein_id="CAA78353.1"
/translation="MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRR
HLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYA
WDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPP
ISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTE
PLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGAL
PGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLD
RESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVV
ITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQY
ILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSY
TAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALII
ATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTS
PFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLE
VSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEP
LLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYL
PRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKD
QDYDYLNEWGNRFKKLADMYGGGEDD"
mat_peptide 557..2740
/product="E-cadherin"
BASE COUNT 1237 a 1177 c 1128 g 1236 t
ORIGIN
1 gcttgcggaa gtcagttcag actccagccc gctccagccc ggcccgaccc gaccgcaccc
61 ggcgcctgcc ctcgctcggc gtccccggcc agccatgggc ccttggagcc gcagcctctc
121 ggcgctgctg ctgctgctgc aggtctcctc ttggctctgc caggagccgg agccctgcca
181 ccctggcttt gacgccgaga gctacacgtt cacggtgccc cggcgccacc tggagagagg
241 ccgcgtcctg ggcagagtga attttgaaga ttgcaccggt cgacaaagga cagcctattt
301 ttccctcgac acccgattca aagtgggcac agatggtgtg attacagtca aaaggcctct
361 acggtttcat aacccacaga tccatttctt ggtctacgcc tgggactcca cctacagaaa
421 gttttccacc aaagtcacgc tgaatacagt ggggcaccac caccgccccc cgccccatca
481 ggcctccgtt tctggaatcc aagcagaatt gctcacattt cccaactcct ctcctggcct
541 cagaagacag aagagagact gggttattcc tcccatcagc tgcccagaaa atgaaaaagg
601 cccatttcct aaaaacctgg ttcagatcaa atccaacaaa gacaaagaag gcaaggtttt
661 ctacagcatc actggccaag gagctgacac accccctgtt ggtgtcttta ttattgaaag
721 agaaacagga tggctgaagg tgacagagcc tctggataga gaacgcattg ccacatacac
781 tctcttctct cacgctgtgt catccaacgg gaatgcagtt gaggatccaa tggagatttt
841 gatcacggta accgatcaga atgacaacaa gcccgaattc acccaggagg tctttaaggg
901 gtctgtcatg gaaggtgctc ttccaggaac ctctgtgatg gaggtcacag ccacagacgc
961 ggacgatgat gtgaacacct acaatgccgc catcgcttac accatcctca gccaagatcc
1021 tgagctccct gacaaaaata tgttcaccat taacaggaac acaggagtca tcagtgtggt
1081 caccactggg ctggaccgag agagtttccc tacgtatacc ctggtggttc aagctgctga
1141 ccttcaaggt gaggggttaa gcacaacagc aacagctgtg atcacagtca ctgacaccaa
1201 cgataatcct ccgatcttca atcccaccac gtacaagggt caggtgcctg agaacgaggc
1261 taacgtcgta atcaccacac tgaaagtgac tgatgctgat gcccccaata ccccagcgtg
1321 ggaggctgta tacaccatat tgaatgatga tggtggacaa tttgtcgtca ccacaaatcc
1381 agtgaacaac gatggcattt tgaaaacagc aaagggcttg gattttgagg ccaagcagca
1441 gtacattcta cacgtagcag tgacgaatgt ggtacctttt gaggtctctc tcaccacctc
1501 cacagccacc gtcaccgtgg atgtgctgga tgtgaatgaa gcccccatct ttgtgcctcc
1561 tgaaaagaga gtggaagtgt ccgaggactt tggcgtgggc caggaaatca catcctacac
1621 tgcccaggag ccagacacat ttatggaaca gaaaataaca tatcggattt ggagagacac
1681 tgccaactgg ctggagatta atccggacac tggtgccatt tccactcggg ctgagctgga
1741 cagggaggat tttgagcacg tgaagaacag cacgtacaca gccctaatca tagctacaga
1801 caatggttct ccagttgcta ctggaacagg gacacttctg ctgatcctgt ctgatgtgaa
1861 tgacaacgcc cccataccag aacctcgaac tatattcttc tgtgagagga atccaaagcc
1921 tcaggtcata aacatcattg atgcagacct tcctcccaat acatctccct tcacagcaga
1981 actaacacac ggggcgagtg ccaactggac cattcagtac aacgacccaa cccaagaatc
2041 tatcattttg aagccaaaga tggccttaga ggtgggtgac tacaaaatca atctcaagct
2101 catggataac cagaataaag accaagtgac caccttagag gtcagcgtgt gtgactgtga
2161 aggggccgcc ggcgtctgta ggaaggcaca gcctgtcgaa gcaggattgc aaattcctgc
2221 cattctgggg attcttggag gaattcttgc tttgctaatt ctgattctgc tgctcttgct
2281 gtttcttcgg aggagagcgg tggtcaaaga gcccttactg cccccagagg atgacacccg
2341 ggacaacgtt tattactatg atgaagaagg aggcggagaa gaggaccagg actttgactt
2401 gagccagctg cacaggggcc tggacgctcg gcctgaagtg actcgtaacg acgttgcacc
2461 aaccctcatg agtgtccccc ggtatcttcc ccgccctgcc aatcccgatg aaattggaaa
2521 ttttattgat gaaaatctga aagcggctga tactgacccc acagccccgc cttatgattc
2581 tctgctcgtg tttgactatg aaggaagcgg ttccgaagct gctagtctga gctccctgaa
2641 ctcctcagag tcagacaaag accaggacta tgactacttg aacgaatggg gcaatcgctt
2701 caagaagctg gctgacatgt acggaggcgg cgaggacgac taggggactc gagagaggcg
2761 ggccccagac ccatgtgctg ggaaatgcag aaatcacgtt gctggtggtt tttcagctcc
2821 cttcccttga gatgagtttc tggggaaaaa aaagagactg gttagtgatg cagttagtat
2881 agctttatac tctctccact ttatagctct aataagtttg tgttagaaaa gtttcgactt
2941 atttcttaaa gctttttttt ttttcccatc actctttaca tggtggtgat gtccaaaaga
3001 tacccaaatt ttaatattcc agaagaacaa ctttagcatc agaaggttca cccagcacct
3061 tgcagatttt cttaaggaat tttgtctcac ttttaaaaag aaggggagaa gtcagctact
3121 ctagttctgt tgttttgtgt atataatttt ttaaaaaaaa tttgtgtgct tctgctcatt
3181 actacactgg tgtgtccctc tgcctttttt ttttttttta agacagggtc tcattctatc
3241 ggccaggctg gagtgcagtg gtgcaatcac agctcactgc agccttgtcc tcccaggctc
3301 aagctatcct tgcacctcag cctcccaagt agctgggacc acaggcatgc accactacgc
3361 atgactaatt ttttaaatat ttgagacggg gtctccctgt gttacccagg ctggtctcaa
3421 actcctgggc tcaagtgatc ctcccatctt ggcctcccag agtattggga ttacagacat
3481 gagccactgc acctgcccag ctccccaact ccctgccatt ttttaagaga cagtttcgct
3541 ccatcgccca ggcctgggat gcagtgatgt gatcatagct cactgtaacc tcaaactctg
3601 gggctcaagc agttctccca ccagcctcct ttttattttt ttgtacagat ggggtcttgc
3661 tatgttgccc aagctggtct taaactcctg gcctcaagca atccttctgc cttggccccc
3721 caaagtgctg ggattgtggg catgagctgc tgtgcccagc ctccatgttt taatatcaac
3781 tctcactcct gaattcagtt gctttgccca agataggagt tctctgatgc agaaattatt
3841 gggctctttt agggtaagaa gtttgtgtct ttgtctggcc acatcttgac taggtattgt
3901 ctactctgaa gacctttaat ggcttccctc tttcatctcc tgagtatgta acttgcaatg
3961 ggcagctatc cagtgacttg ttctgagtaa gtgtgttcat taatgtttat ttagctctga
4021 agcaagagtg atatactcca ggacttagaa tagtgcctaa agtgctgcag ccaaagacag
4081 agcggaacta tgaaaagtgg gcttggagat ggcaggagag cttgtcattg agcctggcaa
4141 tttagcaaac tgatgctgag gatgattgag gtgggtctac ctcatctctg aaaattctgg
4201 aaggaatgga ggagtctcaa catgtgtttc tgacacaaga tccgtggttt gtactcaaag
4261 cccagaatcc ccaagtgcct gcttttgatg atgtctacag aaaatgctgg ctgagctgaa
4321 cacatttgcc caattccagg tgtgcacaga aaaccgagaa tattcaaaat tccaaatttt
4381 ttcttaggag caagaagaaa atgtggccct aaagggggtt agttgagggg tagggggtag
4441 tgaggatctt gatttggatc tctttttatt taaatgtgaa tttcaacttt tgacaatcaa
4501 agaaaagact tttgttgaaa tagctttact gtttctcaag tgttttggag aaaaaaatca
4561 accctgcaat cactttttgg aattgtcttg atttttcggc agttcaagct atatcgaata
4621 tagttctgtg tagagaatgt cactgtagtt ttgagtgtat acatgtgtgg gtgctgataa
4681 ttgtgtattt tctttggggg tggaaaagga aaacaattca agctgagaaa agtattctca
4741 aagatgcatt tttataaatt ttattaaaca attttgtt
//