LOCUS Y18198 1655 bp mRNA linear HUM 24-SEP-2008
DEFINITION Homo sapiens mRNA for ONECUT-2 (OC-2) homeodomain transcription
factor.
ACCESSION Y18198
VERSION Y18198.1
KEYWORDS OC-2 gene; ONECUT-2 transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Jacquemin P., Lannoy V., Rousseau G.G., Lemaigre F.P.
TITLE OC-2, a novel mammalian member of the ONECUT class of homeodomain
transcription factors whose function in liver partially overlaps
with that of hepatocyte nuclear factor-6
JOURNAL J Biol Chem 274(5), 2665-2671(1999).
PUBMED 9915796
REFERENCE 2 (bases 1 to 1655)
AUTHORS Lemaigre F.P.
JOURNAL Submitted (02-OCT-1998) to the INSDC. F.P. Lemaigre, Louvain
University Medical School and, International Institute of Cellular
and, Molecular Pathology, Avenue Hippocrate 75 box 7529, B-1200
Brussels, BELGIUM
FEATURES Location/Qualifiers
source 1..1655
/db_xref="H-InvDB:HIT000326071"
/organism="Homo sapiens"
/chromosome="18"
/map="18q21.1-18q21.2"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="Lambda Zap II, Stratagene"
/cell_type="HeLa"
/db_xref="taxon:9606"
CDS 89..1546
/gene="OC-2"
/product="ONECUT-2 transcription factor (OC-2)"
/db_xref="GOA:O95948"
/db_xref="H-InvDB:HIT000326071.15"
/db_xref="HGNC:HGNC:8139"
/db_xref="InterPro:IPR001356"
/db_xref="InterPro:IPR003350"
/db_xref="InterPro:IPR009057"
/db_xref="InterPro:IPR010982"
/db_xref="UniProtKB/Swiss-Prot:O95948"
/protein_id="CAB38253.1"
/translation="MNPELTMESLGTLHGARGGGSGGGGGGGGGGGGGGPGHEQELLA
SPSPHHARRGPRGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYRP
ELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHH
HHHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLG
GLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGL
HHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQ
AIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC
KRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTT
VSNFFMNARRRSLEKWQDDLSTGGSSSTSSTCTKA"
misc_feature 1027..1224
/gene="OC-2"
/note="cut domain"
misc_feature 1306..1485
/gene="OC-2"
/note="homeodomain"
BASE COUNT 353 a 607 c 473 g 222 t
ORIGIN
1 gcccccgccc gccccgggcc ctgatggact gaatgaaggc tgcctacacc gcctatcgat
61 gcctcaccaa agacctagaa cgtgcgccat gaacccggag ctgacaatgg aaagtctggg
121 cactttgcac ggcgcgcgcg gcggcggcag tggcgggggc ggcggcgggg gcggcggggg
181 cggcggcggg ggcccgggcc atgagcagga gctgctggcc agccccagcc cccaccacgc
241 gcgccgcggc ccgcgtggct cgctgcgggg ccctccgccg cctccaaccg cgcaccagga
301 gctgggcacg gcggcagcgg cggcagcggc ggcgtcgcgc tcggccatgg tcaccagcat
361 ggcctcgatc ctggacggcg gcgactaccg gcccgagctc tccatcccgc tgcaccacgc
421 catgagcatg tcctgcgact cgtctccgcc tggcatgggc atgagcaaca cctacaccac
481 gctgacaccg ctccagccgc tgccacccat ctccaccgtg tctgacaagt tccaccaccc
541 tcacccgcac caccatccgc accaccacca ccaccaccac caccagcgcc tgtccggcaa
601 cgtcagcggc agcttcaccc tcatgcgcga cgagcgcggg ctcccggcca tgaacaacct
661 ctacagtccc tacaaggaga tgcccggcat gagccagagc ctgtccccgc tggccgccac
721 gccgctgggc aacgggctag gcggcctcca caacgcgcag cagagtctgc ccaactacgg
781 tccgccgggc cacgacaaaa tgctcagccc caacttcgac gcgcaccaca ctgccatgct
841 gacccgcggt gagcaacacc tgtcccgcgg cctgggcacc ccacctgcgg ccatgatgtc
901 gcacctgaac ggcctgcacc acccgggcca cactcagtct cacgggccgg tgctggcacc
961 cagtcgcgag cggccaccct cgtcctcatc gggctcgcag gtggccacgt cgggccagct
1021 ggaagaaatc aacaccaaag aggtggccca gcgcatcaca gcggagctga agcgctacag
1081 tatcccccag gcgatctttg cgcagagggt gctgtgccgg tctcagggga ctctctccga
1141 cctgctccgg aatccaaaac cgtggagtaa actcaaatct ggcagggaga ccttccgcag
1201 gatgtggaag tggcttcagg agcccgagtt ccagcgcatg tccgccttac gcctggcagc
1261 gtgcaaacgc aaagagcaag aaccaaacaa agacaggaac aattcccaga agaagtcccg
1321 cctggtgttc actgacctcc aacgccgaac actcttcgcc atcttcaagg agaacaaacg
1381 cccgtcaaag gagatgcaga tcaccatttc ccagcagctg ggcctggagc tcacaaccgt
1441 cagcaacttc ttcatgaacg cccggcgccg cagcctggag aagtggcaag acgatctgag
1501 cacagggggc tcctcgtcca cctccagcac gtgtaccaaa gcatgatgga aggactctca
1561 cttgggcaca agtcacctcc aaatgaggac aacagatacc aaaagaaaac aaaggaaaaa
1621 gacaccggat tcctagctgg ggcccttcac tggtg
//