LOCUS Y17999 2540 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for protein kinase Dyrk1B.
ACCESSION Y17999
VERSION Y17999.1
KEYWORDS Dyrk1B gene; protein kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 2
AUTHORS Becker W.
JOURNAL Submitted (20-AUG-1998) to the INSDC. W. Becker, Inst. fuer
Pharmakologie und Toxikologie, Wendlingweg 2, D- 52057 Aachen, FRG
REMARK revised by [4]
REFERENCE 3
AUTHORS Leder S., Weber Y., Altafaj X., Estivill X., Joost H.G., Becker W.
TITLE Cloning and characterization of DYRK1B, a novel member of the DYRK
family of protein kinases
JOURNAL Biochem. Biophys. Res. Commun. 254(2), 474-479(1999).
PUBMED 9918863
REFERENCE 4 (bases 1 to 2540)
AUTHORS Becker W.
JOURNAL Submitted (08-FEB-1998) to the INSDC. W. Becker, Inst. fuer
Pharmakologie und Toxikologie, Wendlingweg 2, D- 52057 Aachen, FRG
FEATURES Location/Qualifiers
source 1..2540
/db_xref="H-InvDB:HIT000326061"
/organism="Homo sapiens"
/chromosome="19"
/map="19q12-13.11"
/mol_type="mRNA"
/tissue_type="testis"
/db_xref="taxon:9606"
CDS 281..2170
/gene="Dyrk1B"
/product="Dyrk1B protein kinase"
/db_xref="GOA:Q9Y463"
/db_xref="H-InvDB:HIT000326061.14"
/db_xref="HGNC:HGNC:3092"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR028318"
/db_xref="UniProtKB/Swiss-Prot:Q9Y463"
/protein_id="CAA76991.1"
/translation="MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAP
LRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVR
SGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLE
LMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLA
QQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQS
RFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPA
AMLDQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAG
EPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSAST
SPAPLDTCPSSSTASSISSSGGSSGSSSDNRTYRYSNRYCGGPGPPITDCEMNSPQVP
PSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDV
SLVGGPADCSPPHPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPHLGLRGVPQS
TAASS"
CDS join(281..1411,1496..2170)
/gene="Dyrk1B"
/product="Dyrk1B protein kinase"
/note="alternative"
/db_xref="GOA:Q9Y463"
/db_xref="HGNC:HGNC:3092"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR028318"
/db_xref="UniProtKB/Swiss-Prot:Q9Y463"
/protein_id="CAA76989.1"
/translation="MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAP
LRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVR
SGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLE
LMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLA
QQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQS
RFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPA
AMLDQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEDLVLRMLEYEPAARI
SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSS
DNRTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLP
GTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRT
RMTGGRPPLPPPDDPATLGPHLGLRGVPQSTAASS"
CDS join(281..1375,1496..2170)
/gene="Dyrk1B"
/product="Dyrk1B protein kinase"
/note="alternative"
/db_xref="GOA:Q9Y463"
/db_xref="HGNC:HGNC:3092"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR028318"
/db_xref="UniProtKB/Swiss-Prot:Q9Y463"
/protein_id="CAA76990.1"
/translation="MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAP
LRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVR
SGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLE
LMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLA
QQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQS
RFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPA
AMLDQAPKARKYFERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLGALQHGFFR
RTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDNRTYRYSNRYC
GGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPRY
LGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGRPPLPPP
DDPATLGPHLGLRGVPQSTAASS"
regulatory 2517..2522
/gene="Dyrk1B"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 456 a 885 c 741 g 458 t
ORIGIN
1 gggatggggg cggagtccag ggcgtggggg ggccggtttg ttgtggtcgc cattttgctg
61 gttgcattac tgggtaatcg gggccctggc ttgccgcgtc cgccggatac cctcagccag
121 tgggcaggtc tgagctcggg ctccccgagc agtttgagtc cccttgcccg ctccttcagg
181 tctcagcggc ggtggcagcc gaggtgcagg atgcaagaag gcgccccccg gccgggctcc
241 cgctccaggc ctcgctcccc tgcggccctc tgagcccacc atggccgtcc caccgggcca
301 tggtcccttc tctggcttcc cagggcccca ggagcacacg caggtattgc ctgatgtgcg
361 gctactgcct cggaggctgc ccctggcctt ccgggatgca acctcagccc cgctgcgtaa
421 gctctctgtg gacctcatca agacctacaa gcacatcaat gaggtatact atgcgaagaa
481 gaagcggcgg gcccagcagg cgccacccca ggattcgagc aacaagaagg agaagaaggt
541 cctgaaccat ggttatgatg acgacaacca tgactacatc gtgcgcagtg gcgagcgctg
601 gctggagcgc tacgaaattg actcgctcat tggcaaaggc tcctttggcc aggtggtgaa
661 agcctatgat catcagaccc aggagcttgt ggccatcaag atcatcaaga acaaaaaggc
721 tttcctgaac caggcccaga ttgagctgcg gctgctggag ctgatgaacc agcatgacac
781 ggagatgaag tactatatag tacacctgaa gcggcacttc atgttccgga accacctgtg
841 cctggtattt gagctgctgt cctacaacct gtacgacctc ctgcgcaaca cccacttccg
901 cggcgtctcg ctgaacctga cccggaagct ggcgcagcag ctctgcacgg cactgctctt
961 tctggccacg cctgagctca gcatcattca ctgcgacctc aagcccgaaa acatcttgct
1021 gtgcaacccc aagcgcagcg ccatcaagat tgtggacttc ggcagctcct gccagcttgg
1081 ccagaggatc taccagtata tccagagccg cttctaccgc tcacctgagg tgctcctggg
1141 cacaccctac gacctggcca ttgacatgtg gtccctgggc tgcatccttg tggagatgca
1201 caccggagag cccctcttca gtggctccaa tgaggtcgac cagatgaacc gcattgtgga
1261 ggtgctgggc atcccaccgg ccgccatgct ggaccaggcg cccaaggctc gcaagtactt
1321 tgaacggctg cctgggggtg gctggaccct acgaaggacg aaagaactca ggaaggatta
1381 ccagggcccc gggacacggc ggctgcagga ggtgctgggc gtgcagacgg gcgggcccgg
1441 gggccggcgg gcgggggagc cgggccacag ccccgccgac tacctccgct tccaggacct
1501 ggtgctgcgc atgctggagt atgagcccgc cgcccgcatc agccccctgg gggctctgca
1561 gcacggcttc ttccgccgca cggccgacga ggccaccaac acgggcccgg caggcagcag
1621 tgcctccacc tcgcccgcgc ccctcgacac ctgcccctct tccagcaccg ccagctccat
1681 ctccagttct ggaggctcca gtggctcctc cagtgacaac cggacctacc gctacagcaa
1741 ccgatattgt gggggccctg ggccccctat cacagactgt gagatgaaca gcccccaggt
1801 cccaccctcc cagccgctgc ggccctgggc agggggtgat gtgccccaca agacacatca
1861 agcccctgcc tctgcctcgt cactgcctgg gaccggggcc cagttacccc cccagccccg
1921 ataccttggt cgtcccccat caccaacctc accaccaccc ccggagctga tggatgtgag
1981 cctggtgggc ggccctgctg actgctcccc acctcaccca gcgcctgccc cccagcaccc
2041 ggctgcctca gccctccgga ctcggatgac tggaggtcgt ccacccctcc cgcctcctga
2101 tgaccctgcc actctggggc ctcacctggg cctccgtggt gtaccccaga gcacagcagc
2161 cagctcgtga ccctgccccc tccctggggc ccctcctgaa gccataccct cccccatctg
2221 ggggccctgg gctcccatcc tcatctctct ccttgactgg aattgctgct acccagctgg
2281 ggtgggtgag gcctgcactg attggggcct ggggcagggg ggtcaaggag agggttttgg
2341 ccgctccctc cccactaagg actggaccct tgggcccctc tccccctttt tttctattta
2401 ttgtaccaaa gacagtggtg gtccggtgga gggaagaccc cccctcaccc caggacccta
2461 ggagggggtg ggggcaggta gggggagatg gccttgctcc tcctcgctgt acccccagta
2521 aagagctttc tcacaaaaaa
//