LOCUS Y16792 4667 bp DNA linear HUM 14-NOV-2006
DEFINITION Homo sapiens KRTHA6 gene for type I hair keratin 6.
ACCESSION Y16792
VERSION Y16792.1
KEYWORDS Ha6 gene; KRTHA6 gene; type I hair keratin 6.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Rogers M.A., Winter H., Wolf C., Heck M., Schweizer J.
TITLE Characterization of a 190-kilobase pair domain of human type I hair
keratin genes
JOURNAL J Biol Chem 273(41), 26683-26691(1998).
PUBMED 9756910
REFERENCE 2 (bases 1 to 4667)
AUTHORS Schweizer J.
JOURNAL Submitted (04-MAR-1998) to the INSDC. J. Schweizer, German Cancer
Research Center, Research Program 2, Im Neuenheimer Feld 280, 69120
Heidelberg, FRG
FEATURES Location/Qualifiers
source 1..4667
/organism="Homo sapiens"
/chromosome="17"
/map="17q12-21"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
regulatory 598..603
/gene="KRTHA6"
/regulatory_class="TATA_box"
exon 660..1133
/gene="KRTHA6"
/number=1
CDS join(675..1133,1814..1896,2139..2295,2802..2963,
3063..3188,3369..3589,3968..4163)
/gene="KRTHA6"
/product="type I hair keratin 6"
/note="formerly hHa6 gene"
/db_xref="GOA:O76013"
/db_xref="HGNC:HGNC:6454"
/db_xref="InterPro:IPR002957"
/db_xref="InterPro:IPR018039"
/db_xref="InterPro:IPR039008"
/db_xref="InterPro:IPR042180"
/db_xref="UniProtKB/Swiss-Prot:O76013"
/protein_id="CAA76388.1"
/translation="MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAG
AAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLND
RLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSE
NARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVE
SLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENN
RRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLE
STLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIAT
YRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQVGTQIRTITEEI
RDGKVISSREHVQSRPL"
intron 1134..1813
/gene="KRTHA6"
/number=1
exon 1814..1896
/gene="KRTHA6"
/number=2
intron 1897..2138
/gene="KRTHA6"
/number=2
exon 2139..2295
/gene="KRTHA6"
/number=3
intron 2296..2801
/gene="KRTHA6"
/number=3
exon 2802..2963
/gene="KRTHA6"
/number=4
intron 2964..3062
/gene="KRTHA6"
/number=4
exon 3063..3188
/gene="KRTHA6"
/number=5
intron 3189..3368
/gene="KRTHA6"
/number=5
exon 3369..3589
/gene="KRTHA6"
/number=6
intron 3590..3967
/gene="KRTHA6"
/number=6
exon 3968..4382
/gene="KRTHA6"
/number=7
regulatory 4370..4375
/gene="KRTHA6"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 991 a 1251 c 1303 g 1122 t
ORIGIN
1 ccctagtttc agacccaagc tctgccagtc acttcctgtt caccctgagc aagctattaa
61 accattcgga gccccagttt ccacactggt aaaaatgaag ataaaatcag ccacctccta
121 gggttgttac gaggtgtaaa tgaaataaca atgagcctgg tacatcacag gtgctccctg
181 aattttagtt cctttgctcc cttttaccat cccagtagcc caggcagggg tgagcagcta
241 tgaggcgtgg cagcagtgga tggaagtgac aagggacaga tgaggatccc caggggaagg
301 gaggtggaga aagcaggaac caaatgtcat tcgtgcagcc actcccgatt tatgggatct
361 ggtgcagaga ctctttgaag aggcaataaa actcatattc tgctaggaaa tgacaacagt
421 ggagagtcct gacttagcaa accaaattca acgatttcat tttttttttt tttttacaag
481 gcatggggtt ccggatgggt agcaaaaatc acattctaat attagctatc tggggtagga
541 acaggctttc ccaagagcaa gagatgtgta ccatgccaac acccaatggt gagtgtacat
601 aaatgctcca tagaggcctt gagagtccag aacctgagct ccttgctaag ctgcaacctt
661 cctctgctag caccatggcc acccagacct gcacccctac cttctccact gggtctatca
721 agggcctctg tggcacagca ggcggcatct ctcgggtgtc ctccatccgt tctgtgggct
781 cctgcagggt ccccagtctc gccggtgctg cagggtacat ctcttctgct aggtcgggcc
841 tctctggcct tgggagctgc ttgcctggct cctacctgtc ttctgagtgc cacacctctg
901 gctttgtggg gagcgggggc tggttctgcg agggctcctt caacggcagc gagaaggaga
961 ctatgcagtt cctgaacgac cgcctggcca actacctgga gaaggtgcgt cagctggagc
1021 gggagaacgc ggagctggag agccgcatcc aggagtggta cgagtttcag atcccataca
1081 tctgcccaga ctaccagtcc tacttcaaga ccatcgaaga tttccagcag aaggtgaggg
1141 agacctggcc cctttccagc tgagcagccc aactcttagg aggcgtctgt ctcattccag
1201 ggcctttcca gatgggacgg tagcttttag ggaattctcc tggtagggca aacttttctc
1261 tctagggctt tggtttcctg ggggacccag gcttctctgc tggtctcttg cttgtacctt
1321 gttgccagcc gttcctcacc cccctcccct tgctgtagga agggaaggaa catgtaccaa
1381 gcccctaccg gatacagcac tgtgcctgac actttcctat tccctggctt atttattctt
1441 catcttggag agattggtat tactggaccc atctgacaga tgtggaagtt gaattttgag
1501 gggttcagca acttgctcaa gagcacacag gctcagtgtt agatgcagaa cctgaactca
1561 ggtctgcctc accctggtgt atcttgctgt gccactctga aggctacagg cgccaggact
1621 gatggtcact gacatcctcg ggatgcccct gtggggtgga tgctccccca cacctggggt
1681 gtggctcagg gctggaaatg gtgaaggggc tggtggtaca cagtggcatg gcctctgtga
1741 gctgagctat ccccctacct gcccccacac tgctgggcct cctgtagctt atgggaagcc
1801 tcttgttccc cagatcctgc tgactaagtc tgagaatgcc aggctggtcc tgcagattga
1861 taatgccaag ctggctgctg acgacttccg gaccaagtga gtgggcctga tcagggaagg
1921 tttgccatgc cactcccttg cctctgtccc ctgcctttgg gagctggtga tgtgggaata
1981 aggctggatg ggaaaatgtg gcatgagccc tggacctcag gggaaaggag tgtcatgctc
2041 ctgatcccgt cagccactgc agctggacag tagggcaggg gtccctgctg gtgtgtggtt
2101 tcctttgctg cagacttggc agggttctgt gtgtgcaggt atgagacaga gctgtctctg
2161 cggcagctag tggaggccga catcaacggc ctgcgtagga tcctggatga gctgaccctg
2221 tgcaaggctg acctggaggc tcaggtggag tccctgaagg aggagctgat gtgcctcaag
2281 aagaatcacg aggaggtgag gctggtgcca tgtgacttcc cagtgtttcc catccagctt
2341 aggaagccac tgctgggctt tcagttttct gtgcggcagg aactatacaa aggccttgca
2401 tttcattctc gtttcatttc atccttacaa taatcccaag aattataaac tgttacaagc
2461 tccattttac agatgagaaa acttaggcac aaagaggtta agttgcttgc ctaaggtcat
2521 agagggtcta cacttttgcc cataacacta catgtctatt tgggctctag tgtcctgata
2581 acagcaattt aatttgccta gggtttgtat catctcacaa atatcccata gaaggaggta
2641 ggtatatacg gagaaggaga ccaaggctca gagatattta agtatcctgt ctaatgctat
2701 gcagctggtg actgagggaa gagggtttga attcaggtca ttgaaacctg caatccagca
2761 tctttttcac aacctcatgc cgtcttgcct cctctctgca ggaagtcagt gtactccgtt
2821 gccaacttgg ggaccgactg aatgtggagg tggacgctgc tcccccagtg gatctcaaca
2881 agatcctgga ggatatgaga tgccagtacg aggccctggt ggagaataac cgcagagatg
2941 tggaggcctg gttcaacacc caggtggggc tggggtgccc tgggaccaca ggctcctggg
3001 ctggggttac ccttggaagt agcttggttt gaccatgctc tgggccctgg catgtgtttc
3061 agactgagga gctgaaccag caggtggtgt ccagctcgga gcagctgcag tgctgccaga
3121 cggagatcat cgagctgaga cgtacggtca acgcgctaga gattgagctg caggctcagc
3181 acagcatggt gagtggcccc tgcctgcgtc gctggccacg gcctgtggca ggtccccgac
3241 gcaccagcct cagcgtgcag gctctcatgg ggtgtgatca caggtcgtag gcagatgccc
3301 agggctgtgg gtttctgggg tcaggggatt cctccccaat aggcagctct tcctctttcc
3361 cattgcagcg gaattccttg gaatccaccc tggccgaaac cgaggcccgc tacagctccc
3421 agctggccca gatgcagtgc ctgatcagca acgtggaggc ccagctgtct gagatccgct
3481 gcgacctgga gcggcagaac caggagtacc aggtgttact ggacgtcaag gcccggctgg
3541 agggcgagat cgctacctac cgccacctgc tggagggaga ggactgcaag tgagtggccc
3601 ttgggctggg gtagggcttg actgaaccct cagtgccatg tggagggcgt caagcccaga
3661 agtggttgtc gcccagatga agggaactaa accaaagccc cttgagattc tccatttagt
3721 cccaggcttt ggtaatgcac agcgggagaa tccaacccaa cacacgccgc gtgttttccg
3781 ccatcttttc tgattggcag tttctgctct tcattcctgt agctcagtcc tctcaccctt
3841 ggggaattca gaggcactga gatgatccgg ggccaccggt ctcgcttgat cctctagatc
3901 tgtttaacac gaatctcagc ccagtgctcc gatgccaaat gcaccctgca tgattttgtt
3961 tcctcaggct tcctccccaa ccttgtgcca cggcatgcaa gcctgttatt agagttcctt
4021 ctgtcccccc ggtgccctgt gtcccctctg tgccctgcac cccggctccc caggttggca
4081 ctcagatccg caccatcacc gaggagatca gagatgggaa agtcatctcc tccagggagc
4141 acgtgcagtc ccgcccgctg tgacagccca cttggtccac cagggcaggg ccctgaccac
4201 aggaaggagg acacccctgt ggctcctgga ggcttaacga ccctgccctt ctctagaggg
4261 gtccccctac gcttagcagg tttttctacc aaaacactcc ccgtattgtg tttccggact
4321 taactgtgct tttacgccat gcaaaaccag gtttcctgga aatttaccca ataaagtgtg
4381 ttctcctggc atagcaaact caaccctggc tgactctgtt gatgctcatg tgctcgtgtg
4441 gttcatgggg gtgtctgaca ggggctgcag tatagttgtg gggtttccat ttaggtctat
4501 cttctcgggc tctgagtggg aggcggtggc agggtgattt gaagtattta ataacaaaga
4561 tgcctcagag gctggccaat gagaacagac actgacccag tctggatggg tgcggccata
4621 gctctcagct tggccctgcc tgtgagtaga caccttaggg cggcccc
//