LOCUS Y15228 1750 bp mRNA linear HUM 14-NOV-2006
DEFINITION Homo sapiens mRNA for leukemia associated gene 2.
ACCESSION Y15228
VERSION Y15228.1
KEYWORDS LEU2 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Liu Y., Corcoran M., Rasool O., Ivanova G., Ibbotson R.,
Grander D., Iyengar A., Baranova A., Kashuba V., Merup M., Wu X.,
Gardiner A., Mullenbach R., Poltaraus A., Hulstrom A.L.,
Juliusson G., Chapman R., Tiller M., Cotter F., Gahrton G.,
Yankovsky N., Zabarovsky E., Einhorn S., Oscier D.
TITLE Cloning of two candidate tumor suppressor genes within a 10 kb
region on chromosome 13q14, frequently deleted in chronic
lymphocytic leukemia
JOURNAL Oncogene 15(20), 2463-2473(1997).
PUBMED 9395242
REFERENCE 2 (bases 1 to 1750)
AUTHORS Ivanova G.M.
JOURNAL Submitted (24-OCT-1997) to the INSDC. G.M. Ivanova, Radiumhemmet,
Karolinska Hospital, Stockholm, S-17176, SWEDEN
FEATURES Location/Qualifiers
source 1..1750
/db_xref="H-InvDB:HIT000325888"
/organism="Homo sapiens"
/chromosome="13"
/map="q14.3"
/mol_type="mRNA"
/db_xref="taxon:9606"
exon 1..156
/number=1
exon 157..253
/number=2
CDS 241..495
/gene="Leu2"
/db_xref="H-InvDB:HIT000325888.14"
/protein_id="CAA75516.1"
/translation="MRLRFNNDRMKTTIKETTILSSAILTFLTYLMKMSFERCTARNK
MFVNSPFYPRVDNYCTSSWKKFYLKCYFSLNTIKKEKKMT"
exon 254..386
/number=3
exon 387..1735
/number=4
regulatory 1717..1721
/regulatory_class="polyA_signal_sequence"
polyA_site 1735
BASE COUNT 582 a 264 c 279 g 625 t
ORIGIN
1 gatgcctgat ctcatcaatc tagcgggaga gacaggataa cctgtccgag agtatagcgc
61 cacttatgac tccgccggaa aaattacttt aaaaatcgcc aaaaattact tggagcaaag
121 ggcagtccgg cggcgttcgc caaggtggcg cagtcggttt tgacctgtag cagagaacca
181 attctggaga acagcctcac ttctttgatt gaatacttac ataatgcatt ggaacatgac
241 atgagattaa ggtttaataa tgatagaatg aagaccacaa taaaagagac cacaatcctt
301 agctcagcaa ttcttacctt tcttacctat ttgatgaaga tgtcttttga aaggtgtact
361 gcaaggaaca aaatgtttgt aaattctccc ttttacccaa gggtggataa ttactgtacc
421 tcctcatgga aaaagtttta tttaaagtgt tatttctcat tgaatactat caaaaaggaa
481 aaaaaaatga cctaaacttt tgagatagat ttggctctag taagtattta gttatatcac
541 ttgcatatct gggagaagaa ataagagact atcatcagta cattcccatc tactaaaaaa
601 atttatttta cacatgtcaa gggattactt ataacttcca ttttattact aatagcttga
661 acccttttaa tgaagaccta actcctccac cagaaattta agtttatgtt cttactttgt
721 ttacttataa aatacatctc aggtatttcg gatgtctttt ttttttctaa gcctatatga
781 aatgaaaaat atattggcaa agtaaatgtt taaacctttt acgttaaaat tactttgaaa
841 gatgaaaagt tagtgctgtt tttgtcacgt tatactgaaa ttaaatgttt ataatttata
901 ttttgggttt atgtataaat catggaattt atgcaaaaat atgagtagta cagattctcc
961 tctaattctg taggactttg aataatgtga tatttttctt ataattggac ccttgtgttt
1021 tgaagaaatg ccaactgctt gaagaatctc cttgttattt gtattatttg ctatagggtt
1081 agatgttgag aaattctgct gacaaaaaat tttaagccag ttttacacta aatgttcctc
1141 agtctgatta atttgttatt ggatgtattc tgtatctttc ttttgtaatt tgtgactttt
1201 atccacttag cacgaatgat tctattaaag aaaatcatta ggaagtggta gaaactttaa
1261 atcgccccag agtttgcctg tttccatatt ttattatctt ataatcttcg ggagtgctta
1321 cacttatgga gctaacattt tcagagatac agcttcttat agtaacacta aaactttctt
1381 cctctttgga ctgaatacct ataattataa ctatatggta gtttaagttt ccttgtgatt
1441 agtcaaaaat accattttag tatgaagcaa tgaagtctat tatttgttgt cccataattg
1501 agaaagctta aatacacctt ttatgtaaga gtttagtaag attctagctt agtctacaca
1561 gatttttata tcaatttgtt tatattttta ttaatgtcat ttctggaagt gtgaaaatgt
1621 taatgttcaa caagcaacat taaaaataga tttgaaacat ttatatatag agaggtacac
1681 atttatttac tgtttaggta ctgaagatta tcacttaata aaaaatatat atcccaaaaa
1741 aaaaaaaaaa
//