LOCUS Y13620 6267 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for B-cell CLL/lymphoma 9 (BCL9 gene).
ACCESSION Y13620
VERSION Y13620.1
KEYWORDS B-cell CLL/lymphoma 9; BCL9 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Willis T.G., ZALCBERG I.R., Coignet L.J.A., Wlodarska I., STUL M.,
Jadayel D.M., Bastard C., Treleaven J.G., Catovsky D.,
Silva M.L.M., Dyer M.J.S.
TITLE Molecular cloning of translocation t(1;14)(q21;q32) defines a novel
gene (BC19) at chromosome 1q21
JOURNAL Blood 91, 1871-1873(1998).
REFERENCE 2 (bases 1 to 6267)
AUTHORS Willis T.G.
JOURNAL Submitted (05-JUN-1997) to the INSDC. T.G. Willis, Institute of
Cancer Research, Academic Haematology and Cytogenetics, Haddow
Laboratories, Sutton, Surrey SM2 5NG, UK
FEATURES Location/Qualifiers
source 1..6267
/db_xref="H-InvDB:HIT000325784"
/organism="Homo sapiens"
/chromosome="1"
/map="1q21"
/mol_type="mRNA"
/germline
/db_xref="taxon:9606"
CDS 740..4924
/gene="BCL9"
/product="B-cell CLL/lymphoma 9"
/db_xref="GOA:O00512"
/db_xref="H-InvDB:HIT000325784.14"
/db_xref="HGNC:HGNC:1008"
/db_xref="InterPro:IPR015668"
/db_xref="InterPro:IPR024670"
/db_xref="PDB:2GL7"
/db_xref="PDB:2VP7"
/db_xref="PDB:2VPB"
/db_xref="PDB:2VPD"
/db_xref="PDB:2VPE"
/db_xref="PDB:2VPG"
/db_xref="PDB:3SL9"
/db_xref="UniProtKB/Swiss-Prot:O00512"
/protein_id="CAA73942.1"
/translation="MHSSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDS
KFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERS
ISADSFDQRDPGTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQ
TTATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTA
PLNTQISALRNDPKPLPQQPPVPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDR
ESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP
PVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNP
GVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSM
NSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKPEQVVVQQCSLQDMMVHQHGPR
GVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFA
GMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGRGIFSGPGRGERFPNP
QGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPV
EGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREA
GAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLR
NLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVH
SPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSA
AASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPP
PTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIK
TVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSH
SNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQS
PPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSF
TVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQ
PQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPA
FLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSP
GMMMSMQGMMGPNRTS"
BASE COUNT 1509 a 1789 c 1532 g 1437 t
ORIGIN
1 cttccatgtg tgaaagctac ttggcatgaa tgcctgggcc gtaccaagtg tcaccgcagc
61 aagaggggga gtcagaagaa aaacagatca gaccaagcag acaataggcc cctaaagtgt
121 tccccctaag ttgctttgat gttgtcctgg tgtcttgata ccaggaggcc agggattgcg
181 ggaaaagggt cttttttgtc ttcattcact ttcccccctc agtttctgaa atgattctcc
241 agaatttctc ctcataaaaa aggactgaat gtgggcccag ttggcgtcat tctgctttga
301 cctaaacatt cccatctgat tgggtggcag agatcatttt tggaaagttc ttccgtgtcc
361 cgatgtagaa gaaatagcaa attggacata ttgaaagaca agggtcatct ttgagaaggg
421 ggttcctgga ctcctcacct ccaggatgag cactgcagtg tcgtgaccct tggggttttg
481 tatgccctgg agatgcgaga ttttcctctg gcagcaggag gcacgcaccc agagaatgct
541 ggagctgcaa ggggaaagga cccacttcca cagcagagaa aaacaaagag gaaaaaggca
601 tacaggcagc gagcgctaag ggacgcaccc agcaagcagt gggccagtgc cactgccccc
661 agcagctgtt tctgctgcaa cccgagagga actcggtgag cctgtcccgt ttgtgactgc
721 aagctcagga tttcaatcaa tgcattccag taaccctaaa gtgaggagct ctccatcagg
781 aaacacacag agtagcccta agtcaaagca ggaggtgatg gtccgtcccc ctacagtgat
841 gtccccatct ggaaaccccc agctggattc caaattctcc aatcagggta aacagggggg
901 ctcagccagc caatcccagc catccccctg tgactccaag agtgggggcc atacccctaa
961 agcactccct ggcccaggtg ggagcatggg gctgaagaat ggggctggaa atggtgccaa
1021 gggcaagggg aaaagggagc gaagtatttc cgccgactcc tttgatcaga gagatcctgg
1081 gactccaaac gatgactctg acattaaaga atgtaattct gctgaccaca taaagtccca
1141 ggattcccag cacacaccac actcgatgac cccatcaaat gctacagccc ccaggtcttc
1201 taccccctcc catggccaaa ctactgccac agagcccaca cctgctcaga agactccagc
1261 caaagtggtg tacgtgtttt ctactgagat ggccaataaa gctgcagaag ctgttttgaa
1321 gggccaggtt gaaactatcg tctctttcca catccagaac atttctaaca acaagacaga
1381 gagaagcaca gcgcctctga acacacagat atctgccctt cggaatgatc cgaaacctct
1441 cccacaacag cccccagttc cggccaacca ggaccagaat tcttcccaga ataccagact
1501 gcagccaact ccacccattc cggcaccagc acccaagcct gccgcacccc cacgtcccct
1561 ggaccgggag agtcctgggg tagaaaacaa actgattcct tctgtaggaa gtcctgccag
1621 ctccactcca ctgcccccag atggtactgg gcccaactca actcccaaca atagggcagt
1681 gacccctgtc tcccagggga gcaatagctc ttcagcagat cccaaagccc ctccgcctcc
1741 accagtgtcc agtggcgagc cccccacact gggagagaat cccgatggct tatctcagga
1801 gcagctggag caccgggagc gctccttaca aactctcaga gatatccagc gcatgctttt
1861 tcctgatgag aaagaattca caggagcaca aagtggggga ccgcagcaga atcctggggt
1921 attagatggg cctcagaaaa aaccagaagg gccaatacag gccatgatgg cccaatccca
1981 aagcctaggt aagggacctg ggccccggac agacgtggga gctccatttg gccctcaagg
2041 acatagagat gtaccctttt ctccagatga aatggttcca ccttctatga actcccagtc
2101 tgggaccata ggacccgacc accttgacca tatgactccc gagcagatag cgtggctgaa
2161 actgcagcag gagttttatg aagagaagag gaggaagccg gaacaagtgg ttgtccagca
2221 gtgttccctc caggacatga tggtccatca gcacgggcct cggggagtgg tccgaggacc
2281 cccccctcca taccagatga cccctagtga aggctgggca cctgggggta cagagccatt
2341 ttctgatggt atcaacatgc cacattctct gcccccgagg ggcatggctc cccaccccaa
2401 catgccaggg agccagatgc gcctccctgg atttgcaggc atgataaact ctgaaatgga
2461 agggccgaat gtccccaacc ctgcatctag accaggtctt tctggagtca gttggccaga
2521 tgatgtgcca aaaatcccag atggtcgaaa ttttcctcct ggccggggca ttttcagcgg
2581 ccctggccga ggggaacgct tcccaaaccc ccaaggattg tctgaagaga tgtttcagca
2641 gcagctggca gagaaacagc tgggtctccc cccagggatg gccatggaag gcatcaggcc
2701 cagcatggag atgaacagga tgattccagg ctcccagcgc cacatggagc ctgggaataa
2761 ccccattttc cctcgaatac cagttgaggg ccctctgagt ccttctaggg gtgactttcc
2821 aaaaggaatt cccccacaga tgggccctgg tcgggaactt gagtttggga tggttcctag
2881 tgggatgaag ggagatgtca atctaaatgt caacatggga tccaactctc agatgatacc
2941 tcagaagatg agagaggctg gggcgggccc tgaggagatg ctgaaattac gcccaggtgg
3001 ctcagacatg ctgcctgctc agcagaagat ggtgccactg ccatttggtg agcaccccca
3061 gcaggagtat ggcatgggcc ccagaccatt ccttcccatg tctcagggtc caggcagcaa
3121 cagtggcttg cggaatctca gagaaccaat tgggcccgac cagaggacta acagccggct
3181 cagtcatatg ccaccactac ctctcaaccc ttccagtaac cccaccagcc tcaacacagc
3241 tcctccagtt cagcgcggcc tggggcggaa gcccttggat atatctgtgg caggcagcca
3301 ggtgcattcc ccaggcatta accctctgaa gtctcccacg atgcaccaag tccagtcacc
3361 aatgctgggc tcgccctcgg ggaacctcaa gtccccccag actccatcgc agctggcagg
3421 catgctggcg ggcccagctg ctgctgcttc cattaagtcc ccccctgttt tggggtctgc
3481 tgctgcttca cctgtccacc tcaagtctcc atcacttcct gccccgtcac ctggatggac
3541 ctcttctcca aaacctcccc ttcagagtcc tgggatccct ccaaaccata aagcacccct
3601 caccatggcc tccccagcca tgctgggaaa tgtagagtca ggtggccccc cacctcctac
3661 agccagccag cctgcctctg tgaatatccc tggaagtctt ccctctagta caccttatac
3721 catgcctcca gagccaaccc tttcccagaa cccactctct attatgatgt ctcgaatgtc
3781 caagtttgca atgcccagtt ccaccccgtt ataccatgat gctatcaaga ctgtggccag
3841 ctcagatgac gactcccctc cagctcgttc tcccaacttg ccatcaatga ataatatgcc
3901 aggaatgggc attaatacac agaatcctcg aatttcaggt ccaaaccccg tggttccgat
3961 gccaaccctc agcccaatgg gaatgaccca gccactttct cactccaatc agatgccctc
4021 tccaaatgcc gtgggaccca acatacctcc tcatggggtc ccaatggggc ctggcttgat
4081 gtcacacaat cctatcatgg ggcatgggtc ccaagagcca ccgatggtac ctcaaggacg
4141 gatgggcttc ccccagggct tccctccagt acagtctccc ccacagcagg ttccattccc
4201 tcacaatggc cccagtgggg ggcagggcag cttcccagga gggatgggtt tcccaggaga
4261 aggccccctt ggccgcccca gcaacctgcc ccaaagttca gcagatgcag cactttgcaa
4321 gcctggaggc cccgggggtc ctgactcctt cactgtcctg gggaacagca tgccttcggt
4381 gtttacagac ccagatctgc aggaggtcat ccgacctgga gccaccggaa tacctgagtt
4441 tgatctatcc cgcattattc catctgagaa gcccagccag acgctgcaat atttccctcg
4501 aggggaagtt ccaggccgta aacagcccca gggtcctgga cctgggtttt cacacatgca
4561 ggggatgatg ggcgaacaag cccccagaat gggactagca ttacctggca tgggaggtcc
4621 agggccagtg ggaactccgg acatccctct tggtacagct ccatccatgc caggccacaa
4681 ccccatgaga ccaccagcct ttctccaaca aggcatgatg ggacctcacc atcggatgat
4741 gtcaccagca caatctacaa tgcccggcca gcccaccctg atgagcaatc cagctgctgc
4801 cgtgggcatg attcctggca aggatcgggg gcctgccggg ctctacaccc accctgggcc
4861 tgtgggctct ccaggcatga tgatgtccat gcagggcatg atgggaccca acagaacatc
4921 atgatccccc cacagatgag gccccggggc atggctgctg acgtgggcat gggtggattt
4981 agccaaggac ctggcaaccc aggaaacatg atgttttaag ctgctaagat gggatgtgcc
5041 gatccttgtc aaaatgagat tccaggtcct gagagctgct ttgagggagt tccaggagta
5101 cttactattg gtcatgcaat aggagaacag agacccgagg gctgctttgg gggagggggg
5161 aactcgagaa tgtatggatt tacctgaaaa caaattattc atttaatcaa caggtgtgtt
5221 ttttttaaga tttatttttt aaaaattatt tttgtggact tgggtatcaa tgatggcacc
5281 tacttttggg aatctgtagc tgtgctttga gaattgccat cggtcatgtg ttgcaccgtt
5341 ctctgtatgt ttacgtcctt tggactggct tctcccagga ttcttttctg tttttgtttt
5401 tttgatttgg gctttatttt tttctgtgta ctgtactata ttgtaaaagg gattttagca
5461 gagactttag tctttggggc aagaggagaa caggaatgct gggctgttta ctttaggtgg
5521 agaatccatc ttcagacctt tggactattt tctttcaact gcagtgtata gaaaaaccaa
5581 actacgacct cagagcagag tattaatgaa aagcacaaaa aaaggaacta agttcagcga
5641 ggggtggggg gaggggggag atttttcttt tgaaaaataa tgactcttag gacatttgtt
5701 tttaagttca agtgctcttc agcactgtct tgtctcccaa tataccaacc cactggcaca
5761 ttttctctgt ttctctctcc gattttgctc tgtctcctca gttaagtgtt tccttccttt
5821 gtgccccccg ctggtgaccc tctgcttccc tctctctttc cctttggcag ctgcaataca
5881 cagtgttatt ttggggaaat aaatctagca aagcctcgcc ttccatgccg agcgtcctct
5941 tggctctgag agggaaagtc tgtcctggga tgcttctctg tcttttttcc ccctaagtct
6001 ttctctttcc catcataccc ttccctgccc caccttgttt tctgttcccc ttttattagg
6061 aattcccaag tgaattttat taatgtggga gtggaacaga tgctaaaagc tatccaggat
6121 tttgtttctg tttgttttaa attttgtggt tccttccctt tcctccccct cccatgcgta
6181 agacgttctg tgtaacctcc attaaatttg gtacaaaacc actcgccaga gctgtggtgt
6241 cagaaaaata aaatatattg tttctta
//