LOCUS Y12735 2144 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for protein kinase, Dyrk3.
ACCESSION Y12735
VERSION Y12735.2
KEYWORDS dual specificity protein kinase; Dyrk3 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 2
AUTHORS Becker W.
JOURNAL Submitted (22-APR-1997) to the INSDC. W. Becker, Institut fur
Pharmakologie und Toxikologie, Wendlingweg 2, D- 52057 Aachen, FRG
REMARK Revised by [4]
REFERENCE 3
AUTHORS Becker W., Weber Y., Wetzel K., Eirmbter K., Tejedor F.J.,
Joost H.G.
TITLE Sequence characteristics, subcellular localization, and substrate
specificity of DYRK-related kinases, a novel family of dual
specificity protein kinases
JOURNAL J Biol Chem 273(40), 25893-25902(1998).
PUBMED 9748265
REFERENCE 4 (bases 1 to 2144)
AUTHORS Becker W.
JOURNAL Submitted (24-MAY-2000) to the INSDC. W. Becker, Institut fur
Pharmakologie und Toxikologie, Wendlingweg 2, D- 52057 Aachen, FRG
FEATURES Location/Qualifiers
source 1..2144
/db_xref="H-InvDB:HIT000325734"
/organism="Homo sapiens"
/chromosome="1"
/map="q32"
/mol_type="mRNA"
/dev_stage="foetus"
/tissue_type="brain"
/db_xref="taxon:9606"
CDS 149..1915
/gene="Dyrk3"
/product="Dyrk3 protein"
/note="dual specificity protein kinase"
/db_xref="GOA:O43781"
/db_xref="H-InvDB:HIT000325734.14"
/db_xref="HGNC:HGNC:3094"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR042521"
/db_xref="PDB:5Y86"
/db_xref="UniProtKB/Swiss-Prot:O43781"
/protein_id="CAA73266.2"
/translation="MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCP
PCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQS
DGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKL
EIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKG
SFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLE
SFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHC
DLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDI
WSFRCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPR
YCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPS
ARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLK
ANLMSETNGSIPLCSVLPKLIS"
polyA_site 2141
BASE COUNT 599 a 486 c 530 g 529 t
ORIGIN
1 cgggagcgaa agtgcgctga gctgcagtgt ctggtcgaga gtacccgtgg gagcgtcgcg
61 ccgcggaggc agccgtcccg gcgtaggtgg cgtggccgac cggaccccca actggcgcct
121 ctccccgcgc ggggtcccga gctaggagat gggaggcaca gctcgtgggc ctgggcggaa
181 ggatgcgggg ccgcctgggg ccgggctccc gccccagcag cggaggttgg gggatggtgt
241 ctatgacacc ttcatgatga tagatgaaac caaatgtccc ccctgttcaa atgtactctg
301 caatccttct gaaccacctc cacccagaag actaaatatg accactgagc agtttacagg
361 agatcatact cagcactttt tggatggagg tgagatgaag gtagaacagc tgtttcaaga
421 atttggcaac agaaaatcca atactattca gtcagatggc atcagtgact ctgaaaaatg
481 ctctcctact gtttctcagg gtaaaagttc agattgcttg aatacagtaa aatccaacag
541 ttcatccaag gcacccaaag tggtgcctct gactccagaa caagccctga agcaatataa
601 acaccacctc actgcctatg agaaactgga aataattaat tatccagaaa tttactttgt
661 aggtccaaat gccaagaaaa gacatggagt tattggtggt cccaataatg gagggtatga
721 tgatgcagat ggggcctata ttcatgtacc tcgagaccat ctagcttatc gatatgaggt
781 gctgaaaatt attggcaagg ggagttttgg gcaggtggcc agggtctatg atcacaaact
841 tcgacagtac gtggccctaa aaatggtgcg caatgagaag cgctttcatc gtcaagcagc
901 tgaggagatc cggattttgg agcatcttaa gaaacaggat aaaactggta gtatgaacgt
961 tatccacatg ctggaaagtt tcacattccg gaaccatgtt tgcatggcct ttgaattgct
1021 gagcatagac ctttatgagc tgattaaaaa aaataagttt cagggtttta gcgtccagtt
1081 ggtacgcaag tttgcccagt ccatcttgca atctttggat gccctccaca aaaataagat
1141 tattcactgc gatctgaagc cagaaaacat tctcctgaaa caccacgggc gcagttcaac
1201 caaggtcatt gactttgggt ccagctgttt cgagtaccag aagctctaca catatatcca
1261 gtctcggttc tacagagctc cagaaatcat cttaggaagc cgctacagca caccaattga
1321 catatggagt tttcgctgca tccttgcaga acttttaaca ggacagcctc tcttccctgg
1381 agaggatgaa ggagaccagt tggcctgcat gatggagctt ctagggatgc caccaccaaa
1441 acttctggag caatccaaac gtgccaagta ctttattaat tccaagggca taccccgcta
1501 ctgctctgtg actacccagg cagatgggag ggttgtgctt gtggggggtc gctcacgtag
1561 gggtaaaaag cggggtcccc caggcagcaa agactggggg acagcactga aagggtgtga
1621 tgactacttg tttatagagt tcttgaaaag gtgtcttcac tgggacccct ctgcccgctt
1681 gaccccagct caagcattaa gacacccttg gattagcaag tctgtcccca gacctctcac
1741 caccatagac aaggtgtcag ggaaacgggt agttaatcct gcaagtgctt tccagggatt
1801 gggttctaag ctgcctccag ttgttggaat agccaataag cttaaagcta acttaatgtc
1861 agaaaccaat ggtagtatac ccctatgcag tgtattgcca aaactgatta gctagtggac
1921 agagatatgc ccagagatgc atatgtgtat atttttatga tcttacaaac ctgcaaatgg
1981 aaaaaatgca agcccattgg tggatgtttt tgttagagta gacttttttt aaacaagaca
2041 aaacattttt atatgattat aaaagaattc ttcaagggct aattacctaa ccagcttgta
2101 ttggccatct ggaatatgca ttaaatgact ttttataggt caaa
//