LOCUS Y08991 5085 bp mRNA linear HUM 09-SEP-2004
DEFINITION H.sapiens mRNA for adaptor protein p150.
ACCESSION Y08991
VERSION Y08991.1
KEYWORDS adaptor protein; p150 gene; phosphatidylinositol 3-kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Panaretou C., Domin J., Cockcroft S., Waterfield M.D.
TITLE Characterization of p150-a novel adaptor protein for PtdIns
3-kinase
JOURNAL J Biol Chem 272(4), 2477-2485(1997).
PUBMED 8999962
REFERENCE 2 (bases 1 to 5085)
AUTHORS Panaretou C.
JOURNAL Submitted (23-OCT-1996) to the INSDC. C. Panaretou, University
College London, School of Medicine, Ludwig Inst., Courtauld
Building, 91 Riding House Street, London, W1P 8BT, UK
FEATURES Location/Qualifiers
source 1..5085
/db_xref="H-InvDB:HIT000325490"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda ZAP"
/clone="3"
/cell_line="U937"
/db_xref="taxon:9606"
5'UTR 1..567
/gene="p150"
CDS 568..4644
/gene="p150"
/product="adaptor protein"
/db_xref="GOA:Q99570"
/db_xref="H-InvDB:HIT000325490.14"
/db_xref="HGNC:HGNC:8982"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR001680"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR011989"
/db_xref="InterPro:IPR015943"
/db_xref="InterPro:IPR016024"
/db_xref="InterPro:IPR017986"
/db_xref="InterPro:IPR019775"
/db_xref="InterPro:IPR021133"
/db_xref="InterPro:IPR036322"
/db_xref="UniProtKB/Swiss-Prot:Q99570"
/protein_id="CAA70176.1"
/translation="MGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVARAK
HREGLVVVKVFAIQDPTLPLTSYKQELEELKIRLNSAQNCLPFQKASEKASEKAAMLF
RQYVRDNLYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWN
WVLLTDFASFKPTYLPEDNPADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDP
STPLVDLNSNQRTRGELKRAMDIFSAGCVIAELFTEGVPLFDLSQLLAYRNGHFFPEQ
VLNKIEDHSIRELVTQMIHREPDKRLEAEDYLKQQRGNAFPEIFYTFLQPYMAQFAKE
TFLSADERILVIRKDLGNIIHNLCGHDLPEKAEGEPKENGLVILVSVITSCLQTLKYC
DSKLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVRAEALRTLTKVLALVKE
VPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLAETALRFLELVQLKNLNME
NDPNNEEIDEVTHPNGNYDTELQALHEMVQQKVVTLLSDPENIVKQTLMENGITRLCV
FFGRQKANDVLLSHMITFLNDKNDWHLRGAFFDSIVGVAAYVGWQSSSILKPLLQQGL
SDAEEFVIVKALYALTCMCQLGLLQKPHVYEFASDIAPFLCHPNLWIRYGAVGFITVV
ARQISTADVYCKLMPYLDPYITQPIIQIERKLVLLSVLKEPVSRSIFDYALRSKDITS
LFRHLHMRQKKRNGSLPDCPPPEDPAIAQLLKKLLSQGMTEEEEDKLLALKDFMMKSN
KAKANIVDQSHLHDSSQKGVIDLAALGITGRQVDLVKTKQEPDDKRARKHVKQDSNVN
EEWKSMFGSLDPPNMPQALPKGSDQEVIQTGKPPRSESSAGICVPLSTSSQVPEVTTV
QNKKPVIPVLSSTILPSTYQIRITTCKTELQQLIQQKREQCNAERIAKQMMENAEWES
KPPPPGWRPKGLLVAHLHEHKSAVNRIRVSDEHSLFATCSNDGTVKIWNSQKMEGKTT
TTRSILTYSRIGGRVKTLTFCQGSHYLAIASDNGAVQLLGIEASKLPKSPKIHPLQSR
ILDQKEDGCVVDMHHFNSGAQSVLAYATVNGSLVGWDLRSSSNAWTLKHDLKSGLITS
FAVDIHQCWLCIGTSSGTMACWDMRFQLPISSHCHPSRARIRRLSMHPLYQSWVIAAV
QGNNEVSMWDMETGDRRFTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAGSD
MKIRFWDLAYPERSYVVAGSTSSPSVSYYRKIIEGTEVVQEIQNKQKVGPSDDTPRRG
PESLPVGHHDIITDVATFQTTQGFIVTASRDGIVKVWK"
3'UTR 4645..5085
/gene="p150"
BASE COUNT 1467 a 1093 c 1132 g 1393 t
ORIGIN
1 ggatcccccg ggctgcagga attcggcacg aggggagttc ggcgtttgct ggggctgcag
61 cagctgaagt gtagtgtttt cttgggactg gcggtctgca cttctctccc gggttccatc
121 tccccccgcc cggtggtgag gccctcgagg agggctcgga cgggtgtagc gatccgcgct
181 agaggaagac gaggcccggg aacgcatgtc ccccagggca ggttaggggg ctggaggggt
241 caaatcccgg ggtacttgtg gagactcttt agcgtggctt cttctctctg ctgagacccc
301 gagagctttc ccagttctcc tcccaggacc accggggttc ctgaagatcg ggacttttct
361 gcgcccctcc accaacagcc catctcctgt ctatgaagaa agacccttcg tagaaacaac
421 ttccccgctg ctgacgcgtt ttcccgtccc gtccccgaag tagtctacta tgacctcgtt
481 gtgagcctct gaacgatttt gacactttcc cgaggcctag ggtattatat cctaacctta
541 ctaaagacca cagaggtgct tgccattatg ggaaatcagc ttgctggcat tgctccctcc
601 cagatccttt ctgtagagag ttatttttca gatattcatg actttgaata tgataaaagc
661 ctggggagta ctcggttttt taaagttgct cgagccaagc accgagaagg cctggtcgtt
721 gtgaaggttt ttgcaattca ggatcccaca ttgcctttaa ccagctataa acaagagctg
781 gaggaactga aaatcaggct taattctgca cagaattgtc tacctttcca gaaagcatca
841 gaaaaagcat ctgagaaagc agctatgctc tttaggcagt atgtgcgaga caatctctat
901 gatcgcatca gtacccgtcc attcttgaat aacattgaga agcgctggat tgctttccag
961 atcctgacag ctgtggacca agcacacaaa tctggagttc gtcatgggga catcaagact
1021 gagaatgtga tggtcaccag ttggaattgg gttcttctaa ctgattttgc cagttttaag
1081 cccacttatc ttccagaaga caacccggca gatttcaatt atttctttga cacatcacgg
1141 aggagaactt gctatattgc tcctgaacgt tttgttgatg gtgggatgtt tgccactgag
1201 ttagaatata tgagagatcc ttcaactccg cttgtagact taaatagcaa tcagagaaca
1261 agaggagagt tgaagagagc aatggacatc ttttcagcag gttgtgtgat agctgagctt
1321 tttacagaag gtgtaccatt atttgatctc tctcaacttt tggcttatag aaatggacat
1381 tttttccctg aacaagtgct aaataaaatt gaagatcaca gtatcagaga attggtaact
1441 cagatgattc accgtgagcc agataaacgt ttagaggcag aagattactt aaaacagcag
1501 cgtggcaatg cctttcctga aatattttac acttttcttc agccctacat ggcccagttt
1561 gccaaggaaa cgtttctttc tgcagatgag cgtattctgg ttatacggaa ggatttgggc
1621 aacattattc acaatctctg tggacatgat ctgccagaaa aagccgaagg agagcctaag
1681 gaaaatgggc tggttatctt ggtatctgtt ataacatcct gcctacagac ccttaaatac
1741 tgtgattcca aactagctgc tttggaactg attcttcatt tggctccaag attaagtgtt
1801 gaaatccttt tggatcgtat tactccatat cttttgcatt tcagcaatga ctctgttcct
1861 agggtgaggg ctgaagcctt gaggacgttg accaaagttc ttgctctcgt caaagaggtt
1921 cctcgtaatg atatcaatat ttatccggaa tacattctgc caggcatagc ccacttagcc
1981 caagatgatg ctactatcgt tagactagcc tatgctgaaa acatagctct gctggcagaa
2041 acagctctga gattcctgga attagtacag ttaaaaaatc ttaatatgga aaatgacccc
2101 aataatgaag aaatagatga ggttacacat ccaaatggaa attatgacac agagctccaa
2161 gccttacatg aaatggtcca gcagaaagtt gttactttgc taagtgaccc tgaaaatatt
2221 gtaaaacaaa ccttgatgga aaatggaata acacggctgt gtgtattctt tggacgtcag
2281 aaagccaacg atgttttgtt gtcccacatg attactttcc taaatgataa gaatgattgg
2341 catctacgtg gagcattttt tgatagtata gttggtgttg ctgcctatgt tggctggcaa
2401 agctcctcaa ttctcaagcc tctgctgcaa caaggtctta gtgatgctga ggaatttgtc
2461 attgtgaaag ctctttatgc ccttacttgt atgtgccagt taggactgct acaaaaaccc
2521 catgtttacg aatttgccag tgatattgcc cccttcctgt gtcatcccaa tttatggata
2581 cgttatggtg ccgtgggatt tatcacagtg gtagctcgtc aaataagtac agctgatgtc
2641 tactgtaaac tgatgcctta tcttgaccca tatattaccc aaccaataat acagattgaa
2701 agaaaacttg ttctgctcag tgttttaaag gaaccagtaa gtcgttctat atttgattat
2761 gctttgaggt ctaaagatat tactagcttg ttcagacatc ttcacatgcg tcagaagaaa
2821 cgaaatggtt ctcttcccga ctgccctccg ccagaggatc ctgccatagc acagcttctg
2881 aagaagttgc tctcacaggg aatgacagag gaagaggaag acaaacttct ggcactgaaa
2941 gacttcatga tgaaatctaa taaagcaaag gccaatatag tggaccagag ccatcttcat
3001 gatagtagtc agaaaggtgt aattgacttg gcagctttag gcataactgg gagacaagtt
3061 gatcttgtta aaaccaaaca agaaccagat gacaaacggg ccagaaaaca tgtaaaacaa
3121 gactcaaatg taaatgaaga atggaaaagc atgtttgggt cactggaccc accaaacatg
3181 ccacaggccc tacctaaagg gagtgatcag gaggtgattc agactgggaa acctcctcgt
3241 tccgagtcct ctgctggcat ttgtgtccct ttgtcaactt cttcacaggt tccagaagtg
3301 acaactgtcc aaaataaaaa accagtaata ccggttttaa gtagtacaat cttaccatcc
3361 acctatcaga ttcgaattac aacttgtaaa actgaacttc agcaactcat ccagcaaaag
3421 cgggagcagt gcaatgctga gagaatagct aagcagatga tggaaaatgc tgaatgggag
3481 agtaaaccac caccacctgg atggcgtcct aaagggctgt tagttgccca tcttcatgag
3541 cataaatctg ctgtgaatcg aattagagtc tctgatgaac actcactttt tgcaacatgt
3601 tcaaatgatg gcacagtgaa aatctggaac agtcaaaaga tggaggggaa gaccaccact
3661 accagatcta ttcttacata cagccgaatt ggaggacgag tcaagacgct cacattctgc
3721 caaggctccc actatttagc catagcatct gataatggtg ctgtccagct tcttggaatt
3781 gaggcttcta agctgcccaa gtctcctaaa atccatcctc tacaaagcag aattctagat
3841 cagaaggagg acggttgtgt tgtggatatg catcacttca actctggagc acagtctgtt
3901 cttgcctatg ccactgtgaa tggctctctg gttggctggg accttaggtc ttcaagcaat
3961 gcgtggactt taaagcatga tttaaagtcg ggcctcatca cttcctttgc tgtggacatc
4021 caccaatgct ggctctgcat tggtacaagc agtggtacca tggcttgttg ggacatgagg
4081 ttccagttgc caatttcaag tcactgtcat ccttccaggg ctcgaatcag acgcctctca
4141 atgcaccctc tgtatcagtc ctgggtgatt gcagctgttc agggcaacaa cgaagtgtcc
4201 atgtgggaca tggagactgg tgacagaaga tttactctct gggccagcag tgcaccacca
4261 ctttctgaat tacagccttc tcctcatagc gtccatggta tctactgtag tcctgcagat
4321 ggaaatccta tcctactaac agctggctca gatatgaaaa taaggttttg ggacttggct
4381 tacccagaaa ggtcctatgt tgttgcagga agtactagtt ccccatctgt gtcctactac
4441 aggaaaataa ttgaaggcac tgaagttgtc caggaaattc agaataagca gaaagtagga
4501 ccaagtgatg acacccctcg aaggggccca gagtccctgc ccgtgggaca tcatgacatc
4561 atcactgatg tcgccacatt ccagaccaca cagggcttca tcgtaactgc ttctagagat
4621 gggattgtga aggtgtggaa ataaaaccta ctgatttgta taaattttaa tagttataaa
4681 tataatacta taactcgaga aaaggcattt ctagagaaca gattcatttg cttaattttc
4741 aaaattatgt ctccatatta ctgtttcatg actgactgac taaatgacac ccaaaatggt
4801 taagatgtac ttgactagtt tacttatgca tctctttgca agaatcagcc agccaacaat
4861 gtctgggatt tttattgtat atgttataga ggtgagaaat gtaaaatatg aaaatgaata
4921 tgtttatttt gtattgaaaa agatggttga aaagatggtt gtaagctatt atagtataaa
4981 cacatttttg ctattaaaaa tgctattcaa agcagttaaa ctgtaaaaaa aaaaaaaaaa
5041 aaaaaaaaaa aaaaaaaaaa aaaactcgag ggggggcccg gtacc
//