LOCUS Y08686 2026 bp mRNA linear HUM 21-OCT-2008
DEFINITION H.sapiens mRNA for serine palmitoyltransferase, subunit II.
ACCESSION Y08686
VERSION Y08686.1
KEYWORDS serine palmitoyltransferase; subunit II.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 2
AUTHORS Stoffel W.
JOURNAL Submitted (04-OCT-1996) to the INSDC. W. Stoffel, Institute For
Biochemistry, Medical Faculty, University Of Cologne,
Joseph-Stelzmann-Strasse 52, Cologne, 50931, FRG
REMARK revised by [3]
REFERENCE 3 (bases 1 to 2026)
AUTHORS Weiss B.
JOURNAL Submitted (20-OCT-1997) to the INSDC. B.Weiss, Institute For
Biochemistry, Medical Faculty, University Of Cologne,
Joseph-Stelzmann-Strasse 52, Cologne, 50931, FRG
REFERENCE 4
AUTHORS Weiss B., Stoffel W.
TITLE Human and murine serine-palmitoyl-CoA transferase--cloning,
expression and characterization of the key enzyme in sphingolipid
synthesis
JOURNAL Eur. J. Biochem. 249(1), 239-247(1997).
PUBMED 9363775
FEATURES Location/Qualifiers
source 1..2026
/db_xref="H-InvDB:HIT000325468"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="Stratagene #937208"
/cell_line="adenocarcinoma cell line"
/tissue_type="pancreas"
/db_xref="taxon:9606"
CDS 49..1737
/product="serine palmitoyltransferase, subunit II"
/EC_number="2.3.1.50"
/db_xref="GOA:O15270"
/db_xref="H-InvDB:HIT000325468.12"
/db_xref="HGNC:HGNC:11278"
/db_xref="InterPro:IPR001917"
/db_xref="InterPro:IPR004839"
/db_xref="InterPro:IPR015421"
/db_xref="InterPro:IPR015422"
/db_xref="InterPro:IPR015424"
/db_xref="UniProtKB/Swiss-Prot:O15270"
/protein_id="CAA69942.1"
/translation="MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQ
IHHVTQNGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHA
TEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSF
KYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEE
LEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGAT
IRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALK
KKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKK
ELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFR
RRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRA
RFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED"
BASE COUNT 567 a 435 c 529 g 495 t
ORIGIN
1 gctgccaccg cctacagagc ctgccttgcg cctggtgctg ccaggaagat gcggccggag
61 cccggaggct gctgctgccg ccgcacggtg cgggcgaatg gctgcgtggc gaacggggaa
121 gtacggaacg ggtacgtgag gagcagcgct gcagccgcag ccgcagccgc cgccggccag
181 atccatcatg ttacacaaaa tggaggacta tataaaagac cgtttaatga agcttttgaa
241 gaaacaccaa tgctggttgc tgtgctcacg tatgtggggt atggcgtact caccctcttt
301 ggatatcttc gagatttctt gaggtattgg agaattgaaa agtgtcacca tgcaacagaa
361 agagaagaac aaaaggactt tgtgtcattg tatcaagatt ttgaaaactt ttatacaagg
421 aatctgtaca tgaggataag agacaactgg aatcggccaa tctgtagtgt gcctggagcc
481 agggtggaca tcatggagag acagtctcat gattataact ggtccttcaa gtatacaggg
541 aatataataa agggtgttat aaacatgggt tcctacaact atcttggatt tgcacggaat
601 actggatcat gtcaagaagc agccgccaaa gtccttgagg agtatggagc tggagtgtgc
661 agtactcggc aggaaattgg aaacctggac aagcatgaag aactagagga gcttgtagca
721 aggttcttag gagtagaagc tgctatggcg tatggcatgg gatttgcaac gaattcaatg
781 aacattcctg ctcttgttgg caaaggttgc ctgattctga gtgatgaact gaaccatgca
841 tcactggttc tgggagccag actgtcagga gcaaccatta gaatcttcaa acacaacaat
901 atgcaaagcc tagagaagct attgaaagat gccattgttt atggtcagcc tcggacacga
961 aggccctgga agaaaattct catccttgtg gaaggaatat atagcatgga gggatctatt
1021 gttcgtcttc ctgaagtgat tgccctcaag aagaaataca aggcatactt gtatctggat
1081 gaggctcaca gcattggcgc cctgggcccc acaggccggg gtgtggtgga gtactttggc
1141 ctggatcccg aggatgtgga tgttatgatg ggaacgttca caaagagttt tggtgcttct
1201 ggaggatata ttggaggcaa gaaggagctg atagactacc tgcgaacaca ttctcatagt
1261 gcagtgtatg ccacgtcatt gtcacctcct gtagtggagc agatcatcac ctccatgaag
1321 tgcatcatgg ggcaggatgg caccagcctt ggtaaagagt gtgtacaaca gttagctgaa
1381 aacaccaggt atttcaggag acgcctgaaa gagatgggct tcatcatcta tggaaatgaa
1441 gactctccag tagtgccttt gatgctctac atgcctgcca aaattggcgc ctttggacgg
1501 gagatgctga agcggaacat cggtgtcgtt gtggttggat ttcctgccac cccaattatt
1561 gagtccagag ccaggttttg cctgtcagca gctcatacca aagaaatact tgatactgct
1621 ttaaaggaga tagatgaagt tggggaccta ttgcagctga agtattcccg tcatcggttg
1681 gtacctctac tggacaggcc ctttgacgag acgacgtatg aagaaacaga agactgagcc
1741 ttgttggtgc tccctcagag gaactctccc tcacccagga cagcctgtgg cctttgtgag
1801 ccagttccag gaaccacact tctgtggcca tctcacgtga aagacattgc ctcagctact
1861 gaaggtggcc acctccactc taaatgacat tttgtaaata gtaaaaaact gcttctaatc
1921 cttcctttgc taaatctcac ctttaaaaac gaaggtgact cactttgctt tttcagtcca
1981 ttaaaaaaac attttatttt gcaaccaaaa aaaaaaaaaa aaaaaa
//