LOCUS Y07969 1371 bp mRNA linear HUM 03-AUG-1999
DEFINITION H.sapiens mRNA for APRIL protein.
ACCESSION Y07969
VERSION Y07969.1
KEYWORDS acidic protein; APRIL protein; Leucine rich.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 2 (bases 1 to 1371)
AUTHORS Mencinger M.
JOURNAL Submitted (11-SEP-1996) to the INSDC. M. Mencinger, University
Hospital Of Lund, Department Of Clinical Genetics, Lund, S-221 85,
SWEDEN
REFERENCE 4
AUTHORS Mencinger M., Panagopoulos I., Contreras J.A., Mitelman F., Aman P.
TITLE Expression analysis and chromosomal mapping of a novel human gene,
APRIL, encoding an acidic protein rich in leucines
JOURNAL Biochim. Biophys. Acta 1395(2), 176-180(1998).
PUBMED 9473664
FEATURES Location/Qualifiers
source 1..1371
/db_xref="H-InvDB:HIT000325375"
/organism="Homo sapiens"
/chromosome="15"
/map="q25"
/mol_type="mRNA"
/dev_stage="adult"
/tissue_type="pancreas"
/db_xref="taxon:9606"
CDS 231..980
/product="APRIL"
/note="acidic protein rich in leucines"
/db_xref="GOA:Q92688"
/db_xref="H-InvDB:HIT000325375.13"
/db_xref="HGNC:HGNC:16677"
/db_xref="InterPro:IPR001611"
/db_xref="InterPro:IPR003603"
/db_xref="InterPro:IPR032675"
/db_xref="PDB:2ELL"
/db_xref="PDB:2RR6"
/db_xref="UniProtKB/Swiss-Prot:Q92688"
/protein_id="CAA69265.1"
/translation="MKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEF
LSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDIS
TLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEV
DGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDE
EDEDEDEDEEEEEGGKGEKRKRETDDEGEDD"
regulatory 1341..1346
/regulatory_class="polyA_signal_sequence"
polyA_site 1358
BASE COUNT 428 a 280 c 364 g 299 t
ORIGIN
1 tctggttcgg cccacctctg aaggttccag aatcgatagt ggagtaactt ggctccgggg
61 gctccgctcg cctgcccaca cgccgcccgc cacccaggac cgcgccgccg gcctccgccg
121 ctagcaaacc cttccgacgg ccctcgctgc gcaagccggg acgcctctcc cccctccgcc
181 cccgccgcgg aaagttaagt ttgaagaggg gggaagaggg gaacatggac atgaagagga
241 ggatccacct ggagctgagg aaccggaccc cggcagctgt tcgagaactt gtcttggaca
301 attgcaaatc aaatgatgga aaaattgagg gcttaacagc tgaatttgtg aacttagagt
361 tcctcagttt aataaatgta ggcttgatct cagtttcaaa tctccccaag ctgcctaaat
421 tgaaaaagct tgaactcagt gaaaatagaa tctttggagg tctggacatg ttagctgaaa
481 aacttccaaa tctcacacat ctaaacttaa gtggaaataa actgaaagat atcagcacct
541 tggaaccttt gaaaaagtta gaatgtctga aaagcctgga cctctttaac tgtgaggtta
601 ccaacctgaa tgactaccga gagagtgtct tcaagctcct gccccagctt acctacttgg
661 atggctatga ccgagaggac caggaagcac ctgactcaga tgccgaggtg gatggtgtgg
721 atgaagagga ggaggacgaa gaaggagaag atgaggaaga cgaggacgat gaggatggtg
781 aagaagagga gtttgatgaa gaagatgatg aagatgaaga tgtagaaggg gatgaggacg
841 acgatgaagt cagtgaggag gaagaagaat ttggacttga tgaagaagat gaagatgagg
901 atgaggatga agaggaggaa gaaggtggga aaggtgaaaa gaggaagaga gaaacagatg
961 atgaaggaga agatgattaa gaccccagat gacctgcaga aacagaactg ttcagtattg
1021 gttggactgc tcatggattt tgtagctgtt taaaaaaaaa aaaggtagct gtgatacaaa
1081 ccccaggaca cccacccacc caaagagcca aagaatagtt cctgtgacat tccgccttcc
1141 ttccatgtag tccctcttgg taatctacca ccaagcttgt ggacttcacc ccaacaaaat
1201 tgtaagcgtt gttaggtttt tgtgtaagat tcttgctgta gcgtggatag ctgtgattgg
1261 tgagtcaacc gtctgtggct accagttaca ctgagattgt aacagcattt ttactttctg
1321 tacaacaaaa aagctttgta aataaaatct taacatttaa aaaaaaaaaa a
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