LOCUS Y00805 1397 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human mRNA for CD8 T lymphocyte surface glycoprotein beta chain
(mouse and rat Ly-3, Lyt-3 homologue).
ACCESSION Y00805
VERSION Y00805.1
KEYWORDS CD8 antigen; CD8 beta-chain glycoprotein; CD8 glycoprotein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1397)
AUTHORS Parnes J.R.
JOURNAL Submitted (30-NOV-1988) to the INSDC. Parnes J.R., Standford
University, Division of Immunology and Rheumatology S-021,
Standford University Medical Center, Standford , CA 94305.
REFERENCE 2 (bases 1 to 1397)
AUTHORS Shiue L., Gorman S.D., Parnes J.R.
TITLE A second chain of human CD8 is expressed on peripheral blood
lymphocytes
JOURNAL J. Exp. Med. 168(6), 1993-2005(1988).
PUBMED 3264320
FEATURES Location/Qualifiers
source 1..1397
/db_xref="H-InvDB:HIT000325324"
/organism="Homo sapiens"
/chromosome="2."
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 46..678
/note="CD8 beta chain precursor"
/db_xref="GOA:P10966"
/db_xref="H-InvDB:HIT000325324.12"
/db_xref="HGNC:HGNC:1707"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013106"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036179"
/db_xref="InterPro:IPR042414"
/db_xref="UniProtKB/Swiss-Prot:P10966"
/protein_id="CAA68750.1"
/translation="MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAK
ISLSNMRIYWLRQRQAPSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILN
LTSVKPEDSGIYFCMIVGSPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRP
ETQKGPLCSPITLGLLVAGVLVLLVSLGVAIHLCCRRRRARLRFMKQFYK"
sig_peptide 46..108
/note="signal peptide (AA -21 to -1)"
mat_peptide 109..675
/note="mature CD8 beta chain (AA 1-189)"
misc_feature 1376..1381
/note="put. polyA signal"
polyA_site 1397..1397
/note="polyA site"
BASE COUNT 288 a 374 c 391 g 344 t
ORIGIN
1 tgtctccgcc gagcccccgg ggccaggtgt cccgggcgcg ccacgatgcg gccgcggctg
61 tggctcctcc tggccgcgca gctgacagtt ctccatggca actcagtcct ccagcagacc
121 cctgcataca taaaggtgca aaccaacaag atggtgatgc tgtcctgcga ggctaaaatc
181 tccctcagta acatgcgcat ctactggctg agacagcgcc aggcaccgag cagtgacagt
241 caccacgagt tcctggccct ctgggattcc gcaaaaggga ctatccacgg tgaagaggtg
301 gaacaggaga agatagctgt gtttcgggat gcaagccggt tcattctcaa tctcacaagc
361 gtgaagccgg aagacagtgg catctacttc tgcatgatcg tcgggagccc cgagctgacc
421 ttcgggaagg gaactcagct gagtgtggtt gatttccttc ccaccactgc ccagcccacc
481 aagaagtcca ccctcaagaa gagagtgtgc cggttaccca ggccagagac ccagaagggc
541 ccactttgta gccccatcac ccttggcctg ctggtggctg gcgtcctggt tctgctggtt
601 tccctgggag tggccatcca cctgtgctgc cggcggagga gagcccggct tcgtttcatg
661 aaacaatttt acaaataagc agagaatacg gttttggtgt cctgctacaa aaagacatcg
721 gtcagtaatg agcacgatgt ggaaaaatga gagaagggac acattcaacc ctggagagtt
781 caatggctgc tgaagctgcc tgcttttcac tgctgcaagg cctttctgtg tgtgatgtgc
841 atgggagcaa cttgttcgtg ggtcatcggg aatactaggg agaaggtttc attgccccca
901 gggcacttca cagagtgtgc tggaggactg agtaagaaat gctgcccatg ccaccgcttc
961 cggctcctgt gctttccctg aactgggacc tttagtggtg gccatttagc caccatcttt
1021 gcaggttgct ttgccctggt agggccgtaa cattgggtcc tgggtctttc atggggtgat
1081 gctgggctgg ctccctcttg gtcttcccag gctggggctg accttcctcg cagagaggcc
1141 aggtgcaggt tgggaatgag gcttgctgag aggggctgtc cagttcccag aaggcatatc
1201 agtctctgag ggcttccttt ggggccggga acttgcgggt ttgaggatag gagttcactt
1261 catcttctca gctcccattt ttactcttaa gtttctcagc tcccatttct actctcccat
1321 ggcttcatgc ttctttcatt ttctgtttgt tttatacaaa tgtcttagtt gtacaaataa
1381 agtcccaggt taaagat
//