LOCUS Y00762 1667 bp mRNA linear HUM 24-SEP-2008
DEFINITION Human mRNA for muscle acetylcholine receptor alpha-subunit.
ACCESSION Y00762
VERSION Y00762.1
KEYWORDS acetylcholine receptor alpha.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1667)
AUTHORS Schoepfer R.
JOURNAL Submitted (03-FEB-1988) to the INSDC.
REFERENCE 2 (bases 1 to 1667)
AUTHORS Schoepfer R., Luther M., Lindstrom J.
TITLE The human medulloblastoma cell line TE671 expresses a muscle-like
acetylcholine receptor. Cloning of the alpha-subunit cDNA
JOURNAL FEBS Lett. 226(2), 235-240(1988).
PUBMED 3338555
FEATURES Location/Qualifiers
source 1..1667
/db_xref="H-InvDB:HIT000325319"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="1TE"
/clone="pTE1.1"
/cell_line="medulloblastoma TE761"
/db_xref="taxon:9606"
CDS 49..1422
/note="precursor (AA -20 to 437)"
/db_xref="GOA:P02708"
/db_xref="H-InvDB:HIT000325319.14"
/db_xref="HGNC:HGNC:1955"
/db_xref="InterPro:IPR002394"
/db_xref="InterPro:IPR006029"
/db_xref="InterPro:IPR006201"
/db_xref="InterPro:IPR006202"
/db_xref="InterPro:IPR018000"
/db_xref="InterPro:IPR036719"
/db_xref="InterPro:IPR036734"
/db_xref="PDB:1Y5P"
/db_xref="PDB:1Y5T"
/db_xref="PDB:1Y6C"
/db_xref="PDB:4ZJS"
/db_xref="PDB:5HBT"
/db_xref="UniProtKB/Swiss-Prot:P02708"
/protein_id="CAA68731.1"
/translation="MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVED
HRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPS
EKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQ
NCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPY
LDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVF
LLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRK
VFIDTIPNIMFFSTMKRPSREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEV
KSAIEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRL
IELNQQG"
sig_peptide 49..108
/note="signal peptide (AA -20 to -1)"
mat_peptide 109..1419
/note="mature alpha-chain (AA 1-437)"
misc_feature 529..531
/note="pot. N-glycosylation site"
BASE COUNT 419 a 465 c 371 g 412 t
ORIGIN
1 aagcacaggc caccactctg ccctggtcca cacaagctcc ggtagcccat ggagccctgg
61 cctctcctcc tgctctttag cctttgctca gctggcctcg tcctgggctc cgaacatgag
121 acccgtctgg tggcaaagct atttaaagac tacagcagcg tggtgcggcc agtggaagac
181 caccgccagg tcgtggaggt caccgtgggc ctgcagctga tacagctcat caatgtggat
241 gaagtaaatc agatcgtgac aaccaatgtg cgtctgaaac agcaatgggt ggattacaac
301 ctaaaatgga atccagatga ctatggcggt gtgaaaaaaa ttcacattcc ttcagaaaag
361 atctggcgcc cagaccttgt tctctataac aatgcagatg gtgactttgc tattgtcaag
421 ttcaccaaag tgctcctgca gtacactggc cacatcacgt ggacacctcc agccatcttt
481 aaaagctact gtgagatcat cgtcacccac tttccctttg atgaacagaa ctgcagcatg
541 aagctgggca cctggaccta cgacggctct gtcgtggcca tcaacccgga aagcgaccag
601 ccagacctga gcaacttcat ggagagcggg gagtgggtga tcaaggagtc ccggggctgg
661 aagcactccg tgacctattc ctgctgcccc gacaccccct acctggacat cacctaccac
721 ttcgtcatgc agcgcctgcc cctctacttc atcgtcaacg tcatcatccc ctgcctgctc
781 ttctccttct taactggcct ggtattctac ctgcccacag actcagggga gaagatgact
841 ctgagcatct ctgtcttact gtctttgact gtgttccttc tggtcatcgt ggagctgatc
901 ccctccacgt ccagtgctgt gcccttgatt ggaaaataca tgctgttcac catggtgttc
961 gtcattgcct ccatcatcat cactgtcatc gtcatcaaca cacaccaccg ctcacccagc
1021 acccatgtca tgcccaactg ggtgcggaag gtttttatcg acactatccc aaatatcatg
1081 tttttctcca caatgaaaag accatccaga gaaaagcaag acaaaaagat ttttacagaa
1141 gacattgata tctctgacat ttctggaaag ccagggcctc cacccatggg cttccactct
1201 cccctgatca aacaccccga ggtgaaaagt gccatcgagg gcatcaagta catcgcagag
1261 accatgaagt cagaccagga gtctaacaat gcggcggcag agtggaagta cgttgcaatg
1321 gtgatggacc acatactcct cggagtcttc atgcttgttt gcatcatcgg aaccctagcc
1381 gtgtttgcag gtcgactcat tgaattaaat cagcaaggat gagcagaaaa tgagctgagc
1441 ttagctctgc cctggaacct accagagcag agaagggcag gagaggaaga tttgtctact
1501 tgctccactc gcacttatca aacgtgttat attccatact tattattgat gataagattt
1561 acctttatgt aagtttatgg ccttgaagtg ttttcatatt gcttctccct ttagttctgc
1621 tgtctccctg aagagtgaac cctctttagt aaatgaaact aatcact
//