LOCUS Y00661 4714 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human bcr mRNA (break point cluster gene).
ACCESSION Y00661
VERSION Y00661.1
KEYWORDS bcr gene; break point cluster gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4714)
AUTHORS Canaani E.
JOURNAL Submitted (04-DEC-1987) to the INSDC. Canaani E., Dep. Chemical
Immunology , The Weizman Institute of Science , Israel.
REFERENCE 2
AUTHORS Lifshitz B., Fainstein E., Marcelle C., Shtivelman E., Amson R.,
Gale R.P., Canaani E.
TITLE bcr genes and transcripts
JOURNAL Oncogene 2(2), 113-117(1988).
PUBMED 3285291
FEATURES Location/Qualifiers
source 1..4714
/db_xref="H-InvDB:HIT000325302"
/organism="Homo sapiens"
/map="chromosome 22"
/mol_type="mRNA"
/clone_lib="K562 cDNA tissue=liver developmental
stage=fetal"
/db_xref="taxon:9606"
CDS 597..4280
/note="bcr polypeptide"
/db_xref="GOA:P11274"
/db_xref="H-InvDB:HIT000325302.14"
/db_xref="HGNC:HGNC:1014"
/db_xref="InterPro:IPR000008"
/db_xref="InterPro:IPR000198"
/db_xref="InterPro:IPR000219"
/db_xref="InterPro:IPR001331"
/db_xref="InterPro:IPR001849"
/db_xref="InterPro:IPR008936"
/db_xref="InterPro:IPR015123"
/db_xref="InterPro:IPR035892"
/db_xref="InterPro:IPR035899"
/db_xref="InterPro:IPR036481"
/db_xref="InterPro:IPR037769"
/db_xref="PDB:1K1F"
/db_xref="PDB:2AIN"
/db_xref="PDB:5N6R"
/db_xref="PDB:5N7E"
/db_xref="PDB:5OC7"
/db_xref="UniProtKB/Swiss-Prot:P11274"
/protein_id="CAA68676.1"
/translation="MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRR
LEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPA
DGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFER
IRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHG
AGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEY
QPYQSIYVGGIMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSS
NENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRH
RHCPVVVSEATIVGVRKTGQIWPNDDEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ
DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALKSTKASELDLEKGLEMRKWVLSGILA
SEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKESYDGLFP
RVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRA
RSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQ
NFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKL
KKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKSDI
QREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAE
WRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLN
VIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNELDPQALQDRDWQ
RTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQC
VEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYF
RELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVA
EKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLY
FLQLEAIPAPDSKRQSILFSTEV"
BASE COUNT 962 a 1492 c 1514 g 746 t
ORIGIN
1 ggggggaggg tggcggctcg atgggggagc cgccccaggg ggcccccccg ccctgtgccc
61 acggcgcggc ccctttaagg aggcccgcct ggctccgctc catcgcgcat cgcggccgcc
121 tccccccggc cctcccttcc tgcggcgcag agtgcgggcc gggcgggagt gcggcgagcc
181 ggctggctta gcgtccgagg aggcggcggc ggcggcggcg gcagcggcgg cggcggggct
241 ggtggggcgg tgcggaagcg agaggcgagg agcgcgcggg ccgtggccag agtctggcgg
301 cggcctggcg gagcggagag cagcgcccgc gcctcgccgt gcggaggagc cccgcacaca
361 atagcggcgc gcgcagcccg cgcccttccc cccggcgcgc cccgccccgc gcgccgagcg
421 ccccgctccg cctcacctgc caccagggag tgggcgggca ttgttcgccg ccgccgccgc
481 cgcgcggggc catgggggcc gcccggcgcc cggggccggg cctggcgagg ccgccgcgcc
541 gccgctgaga cgggccccgc gcgcagcccg gcggcgcagg taaggccggc cgcgccatgg
601 tggacccggt gggcttcgcg gaggcgtgga aggcgcagtt cccggactca gagcccccgc
661 gcatggagct gcgctcagtg ggcgacatcg agcaggagct ggagcgctgc aaggcctcca
721 ttcggcgcct ggagcaggag gtgaaccagg agcgcttccg catgatctac ctgcagacgt
781 tgctggccaa ggaaaagaag agctatgacc ggcagcgatg gggcttccgg cgcgcggcgc
841 aggcccccga cggcgcctcc gagccccgag cgtccgcgtc gcgcccgcag ccagcgcccg
901 ccgacggagc cgacccgccg cccgccgagg agcccgaggc ccggcccgac ggcgagggtt
961 ctccgggtaa ggccaggccc gggaccgccc gcaggcccgg ggcagccgcg tcgggggaac
1021 gggacgaccg gggacccccc gccagcgtgg cggcgctcag gtccaacttc gagcggatcc
1081 ggaagggcca tggccagccc ggggcggacg ccgagaagcc cttctacgtg aacgtcgagt
1141 ttcaccacga gcgcggcctg gtgaaggtca acgacaaaga ggtgtcggac cgcatcagct
1201 cccttggcag ccaggccatg cagatggagc gcaaaaagtc ccagcacggc gcgggctcga
1261 gcgtggggga tgcatccagg cccccttacc ggggacgctc ctcggagagc agctgcggcg
1321 tcgacggcga ctacgaggac gccgagttga acccccgctt cctgaaggac aacctgatcg
1381 acgccaatgg cggtagcagg cccccttggc cgcccctgga gtaccagccc taccagagca
1441 tctacgtcgg gggcatcatg gaaggggagg gcaagggccc gctcctgcgc agccagagca
1501 cctctgagca ggagaagcgc cttacctggc cccgcaggtc ctactccccc cggagttttg
1561 aggattgcgg aggcggctat accccggact gcagctccaa tgagaacctc acctccagcg
1621 aggaggactt ctcctctggc cagtccagcc gcgtgtcccc aagccccacc acctaccgca
1681 tgttccggga caaaagccgc tctccctcgc agaactcgca acagtccttc gacagcagca
1741 gtccccccac gccgcagtgc cataagcggc accggcactg cccggttgtc gtgtccgagg
1801 ccaccatcgt gggcgtccgc aagaccgggc agatctggcc caacgatgac gagggcgcct
1861 tccatggaga cgcagatggc tcgttcggaa caccacctgg atacggctgc gctgcagacc
1921 gggcagagga gcagcgccgg caccaagatg ggctgcccta cattgatgac tcgccctcct
1981 catcgcccca cctcagcagc aagggcaggg gcagccggga tgcgctggtc tcgggagccc
2041 tgaagtccac taaagcgagt gagctggact tggaaaaggg cttggagatg agaaaatggg
2101 tcctgtcggg aatcctggct agcgaggaga cttacctgag ccacctggag gcactgctgc
2161 tgcccatgaa gcctttgaaa gccgctgcca ccacctctca gccggtgctg acgagtcagc
2221 agatcgagac catcttcttc aaagtgcctg agctctacga gatccacaag gagtcctatg
2281 atgggctctt cccccgcgtg cagcagtgga gccaccagca gcgggtgggc gacctcttcc
2341 agaagctggc cagccagctg ggtgtgtacc gggccttcgt ggacaactac ggagttgcca
2401 tggaaatggc tgagaagtgc tgtcaggcca atgctcagtt tgcagaaatc tccgagaacc
2461 tgagagccag aagcaacaaa gatgccaagg atccaacgac caagaactct ctggaaactc
2521 tgctctacaa gcctgtggac cgtgtgacga ggagcacgct ggtcctccat gacttgctga
2581 agcacactcc tgccagccac cctgaccacc ccttgctgca ggacgccctc cgcatctcac
2641 agaacttcct gtccagcatc aatgaggaga tcacaccccg acggcagtcc atgacggtga
2701 agaagggaga gcaccggcag ctgctgaagg acagcttcat ggtggagctg gtggaggggg
2761 cccgcaagct gcggcacgtc ttcctgttca ccgacctgct tctctgcacc aagctcaaga
2821 agcagagcgg aggcaaaacg cagcagtatg actgcaaatg gtacattccg ctcacggatc
2881 tcagcttcca gatggtggat gaactggagg cagtgcccaa catccccctg gtgcccgatg
2941 aggagctgga cgctttgaag atcaagatct cccagatcaa gagtgacatc cagagagaga
3001 agagggcgaa caagggcagc aaggctacgg agaggctgaa gaagaagctg tcggagcagg
3061 agtcactgct gctgcttatg tctcccagca tggccttcag ggtgcacagc cgcaacggca
3121 agagttacac gttcctgatc tcctctgact atgagcgtgc agagtggagg gagaacatcc
3181 gggagcagca gaagaagtgt ttcagaagct tctccctgac atccgtggag ctgcagatgc
3241 tgaccaactc gtgtgtgaaa ctccagactg tccacagcat tccgctgacc atcaataagg
3301 aagatgatga gtctccgggg ctctatgggt ttctgaatgt catcgtccac tcagccactg
3361 gatttaagca gagttcaaat ctgtactgca ccctggaggt ggattccttt gggtattttg
3421 tgaataaagc aaagacgcgc gtctacaggg acacagctga gccaaactgg aacgagctgg
3481 acccgcaggc cctgcaggac agagactggc agcgcaccgt catcgccatg aatgggatcg
3541 aagtaaagct ctcggtcaag ttcaacagca gggagttcag cttgaagagg atgccgtccc
3601 gaaaacagac aggggtcttc ggagtcaaga ttgctgtggt caccaagaga gagaggtcca
3661 aggtgcccta catcgtgcgc cagtgcgtgg aggagatcga gcgccgaggc atggaggagg
3721 tgggcatcta ccgcgtgtcc ggtgtggcca cggacatcca ggcactgaag gcagccttcg
3781 acgtcaataa caaggatgtg tcggtgatga tgagcgagat ggacgtgaac gccatcgcag
3841 gcacgctgaa gctgtacttc cgtgagctgc ccgagcccct cttcactgac gagttctacc
3901 ccaacttcgc agagggcatc gctctttcag acccggttgc aaaggagagc tgcatgctca
3961 acctgctgct gtccctgccg gaggccaacc tgctcacctt ccttttcctt ctggaccacc
4021 tgaaaagggt ggcagagaag gaggcagtca ataagatgtc cctgcacaac ctcgccacgg
4081 tctttggccc cacgctgctc cggccctccg agaaggagag caagctccct gccaacccca
4141 gccagcctat caccatgact gacagctggt ccttggaggt catgtcccag gtccaggtgc
4201 tgctgtactt cctgcagctg gaggccatcc ctgccccgga cagcaagaga cagagcatcc
4261 tgttctccac cgaagtctaa aggtcccagt ccatctcctg gaggcagaca gatggcctgg
4321 aaacctctgg ctaatcgggc catccgtaga gcgggaacct tcctgaggtg tccttgggcc
4381 acccccaagt gttgggccat ctgccaagag acagcgaccc aaagccgaag gacaggtggc
4441 ctgggcagat ctgcccaggt ctgggagccc caagctggcc tcagactgtg gttttttatg
4501 tggccacccg agggcgcccc aagccagttc atctcggagt ccaggcctga ccctgggaga
4561 cagggtgaag ggagtgattt ttatgaactt aacttagagt ctaaaagatt tctactggat
4621 cacttgtcaa gatgcgccct ctctggggag aagggaacgt gaccggattc cctcactgtt
4681 gtatcttgaa taaacgctgc tgcttcaaaa aaaa
//