LOCUS X99142 2046 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for hair keratin, hHb6.
ACCESSION X99142
VERSION X99142.1
KEYWORDS hHb6 gene; keratin; type II intermediate filament.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Rogers M.A., Langbein L., Praetzel S., Krieg T., Winter H.,
Schweizer J.
TITLE Sequences and differential expression of three novel human type-II
hair keratins
JOURNAL Differentiation 61(3), 187-194(1997).
PUBMED 9084137
REFERENCE 2 (bases 1 to 2046)
AUTHORS Schweizer J.
JOURNAL Submitted (06-JUL-1996) to the INSDC. J. Schweizer, German Cancer
Research Center, Institute of Experimental Pathology, Im
Neuenheimer Feld 280, D-69120 Heidelberg, Germany, FRG
FEATURES Location/Qualifiers
source 1..2046
/db_xref="H-InvDB:HIT000325182"
/organism="Homo sapiens"
/map="17q12-21"
/mol_type="mRNA"
/clone_lib="human scalp cDNA in Lambda Zap-II"
/clone="phKII-6"
/db_xref="taxon:9606"
CDS <1..1452
/codon_start=1
/gene="hHb6"
/product="type II intermediate filament of hair keratin"
/db_xref="GOA:O43790"
/db_xref="H-InvDB:HIT000325182.14"
/db_xref="HGNC:HGNC:6463"
/db_xref="InterPro:IPR003054"
/db_xref="InterPro:IPR018039"
/db_xref="InterPro:IPR032444"
/db_xref="InterPro:IPR039008"
/db_xref="InterPro:IPR042180"
/db_xref="UniProtKB/Swiss-Prot:O43790"
/protein_id="CAA67579.1"
/translation="GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGS
HSVCGGFRAGSCGRDFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQE
EKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLR
REAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR
KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIK
AQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE
NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS
KLGLDIEIATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRV
SSVPSNSNVVVGTTNACAPSARVGVCGGSCKRC"
regulatory 2007..2012
/regulatory_class="polyA_signal_sequence"
BASE COUNT 398 a 616 c 638 g 394 t
ORIGIN
1 ggatcttact gtggtggccg cgccttcagc tgcatctcgg cctgtgggcc ccggcccggc
61 cgctgctgca tcaccgctgc cccctaccgt ggcatctcct gctaccgcgg cctcaccggg
121 ggcttcggca gccacagcgt gtgcggaggc tttcgggccg gctcctgcgg acgcgacttc
181 ggctaccgct ccgggggcgt gtgcgggccc agtcccccat gcatcaccac cgtgtcggtc
241 aacgagagcc tcctcacgcc cctcaacctg gagatcgacc ccaacgcgca gtgcgtgaag
301 caggaggaga aggagcagat caagtccctc aacagcagat tcgcggcctt catcgacaag
361 gtgcgcttcc tggagcagca gaacaaactg ctggagacaa agctgcagtt ctaccagaac
421 cgcgagtgtt gccagagcaa cctggagccc ctgtttgagg gctacatcga gactctgcgg
481 cgggaggccg agtgcgtgga ggccgacagc gggaggctgg cctcagagct taaccacgtg
541 caggaggtgc tggagggcta caagaagaag tatgaggagg aggtttctct gagagcaaca
601 gctgagaacg agtttgtggc tctgaagaag gatgtggact gcgcctacct ccgcaaatca
661 gacctggagg ccaatgtgga ggccctgatc caggagatcg acttcctgag gcggctgtat
721 gaggaggaga tccgcgttct ccagtcccac atctcagaca cctccgtggt tgtcaagctg
781 gacaacagcc gggacctgaa catggactgc atcattgccg agatcaaggc acagtacgat
841 gacattgtca cccgtagccg ggctgaggcc gagtcctggt accgcagcaa gtgtgaggag
901 atgaaggcca cggtgatcag gcacggggag accctgcgcc gcaccaagga ggagatcaac
961 gagctgaacc gcatgatcca gaggctgacg gctgaggtgg agaatgccaa gtgccagaat
1021 tccaagctgg aggctgcggt ggctcagtct gagcagcagg gtgaggcggc cctcagcgat
1081 gcccgctgca agttggccga gctggagggt gccctgcaga aggccaagca ggacatggcc
1141 tgcctgatca gggagtacca ggaggtgatg aactccaagc tgggcctgga catcgagatc
1201 gccacctaca ggcgcctgct ggagggcgag gagcagaggc tgtgcgaggg cgtcggctcg
1261 gtgaatgtct gcgtcagcag ctcccgcggt ggcgttgtct gtggcgatct ctgcgcctcc
1321 actactgccc ctgttgtctc caccagagtc agtagcgtcc ccagcaacag caacgtggtg
1381 gtgggcacta ctaacgcctg cgccccctcc gcccgggttg gcgtctgcgg cggcagctgt
1441 aagaggtgct aggaggctgc cgcctccgcc agcgcctgtc gccgtcactc tccacccagc
1501 cagtacctcg cgccaggaga acgcgccgcc cgcgccggcc tcccaatagc cgccgcccgc
1561 tgcctgcact ctaagcgctc tccccacgtc cgctccggga gccatccccg gtcgcaggag
1621 tccggggagg gccgggaggc gccatggtct ctctctgtag cctttcctgg tagtcaattt
1681 gttgtcccga ggattcatct ttttcttcct cctaccttct gttttttttt tcatgtatgc
1741 attggtcttg cctgagctct tcctcaaagc ttggaggaac gggggagggc ccgggaatgt
1801 ccctgtctgc acgacctggg actctgccca tgtgcttttg cctgtggaat ggagacgcgg
1861 accctggata gtggttctat gactctgcga gggacaggcc cacgcgtgtg gggagaacat
1921 ctccttccgg ggctgccctc aagagcttct gaaaaactaa tgactctgct gccttctcct
1981 ttgtctttgt ttcactctgt gtttccaata aactcattgt agcgaatcaa aaaaaaaaaa
2041 aaaaaa
//