LOCUS X99140 2454 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for hair keratin, hHb5.
ACCESSION X99140
VERSION X99140.1
KEYWORDS hHb5 gene; keratin; type II intermediate filament.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Rogers M.A., Langbein L., Praetzel S., Krieg T., Winter H.,
Schweizer J.
TITLE Sequences and differential expression of three novel human type-II
hair keratins
JOURNAL Differentiation 61(3), 187-194(1997).
PUBMED 9084137
REFERENCE 2 (bases 1 to 2454)
AUTHORS Schweizer J.
JOURNAL Submitted (06-JUL-1996) to the INSDC. J. Schweizer, German Cancer
Research Center, Institute of Experimental Pathology, Im
Neuenheimer Feld 280, D-69120 Heidelberg, Germany, FRG
FEATURES Location/Qualifiers
source 1..2454
/db_xref="H-InvDB:HIT000325180"
/organism="Homo sapiens"
/map="17q12-21"
/mol_type="mRNA"
/clone_lib="human scalp cDNA in Lambda Zap-II"
/clone="phKII-5"
/db_xref="taxon:9606"
CDS 67..1590
/gene="hHb5"
/product="type II intermediate filament of hair keratin"
/db_xref="GOA:P78386"
/db_xref="H-InvDB:HIT000325180.14"
/db_xref="HGNC:HGNC:6462"
/db_xref="InterPro:IPR003054"
/db_xref="InterPro:IPR018039"
/db_xref="InterPro:IPR032444"
/db_xref="InterPro:IPR039008"
/db_xref="InterPro:IPR042180"
/db_xref="UniProtKB/Swiss-Prot:P78386"
/protein_id="CAA67577.1"
/translation="MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSC
YRGLTGFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNE
SLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQN
QRCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALR
ATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSV
IVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRR
TKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGAL
QKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGSVNVCVSSSRG
GVSCGGLSYSTTPGRQITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSSRSVRFA"
regulatory 2416..2421
/regulatory_class="polyA_signal_sequence"
BASE COUNT 513 a 740 c 716 g 485 t
ORIGIN
1 tgagcctcgc actctgccgc ccgcaccacc ttccgctgcc tctcagactc tgctcagcct
61 cacacgatgt cgtgccgctc ctacaggatc agctcaggat gcggggtcac caggaacttc
121 agctcctgct cagctgtggc ccccaaaact ggcaaccgct gctgcatcag cgccgccccc
181 taccgagggg tgtcctgcta ccgagggctg acgggcttcg gcagccgcag cctctgcaac
241 ctgggctcct gcgggccccg gatagctgta ggtggcttcc gagccggctc ctgcggacgc
301 agcttcggct accgctccgg gggcgtgtgc ggacccagcc ccccatgcat cactaccgtg
361 tcggtcaacg agagcctcct cacgcccctc aacctggaga tcgaccccaa cgcacagtgc
421 gtgaagcagg aggagaagga gcagatcaag tccctcaaca gcaggttcgc ggccttcatc
481 gacaaggtgc gcttcctgga gcagcagaac aagctgctgg agaccaagtg gcagttctac
541 cagaaccagc gctgctgcga gagcaacctg gagccactgt tcagtggcta catcgagact
601 ctgcggcggg aggccgagtg cgtggaggcc gacagcggga ggctggcctc agagctcaac
661 catgtgcagg aggtgctgga gggctacaag aagaagtatg aagaggaggt ggccctgaga
721 gccacagcag agaatgagtt tgtcgttcta aagaaggacg tggactgtgc ctacctgcgg
781 aaatcagacc tggaggccaa tgtggaggcc ctggtggagg agtctagctt cctgaggcgc
841 ctctatgaag aggagatccg cgttctccaa gcccacatct cagacacctc ggtcatagtc
901 aagatggaca acagccgaga cctgaacatg gactgcatca tcgctgagat caaggctcag
961 tatgacgatg ttgccagccg cagccgggcc gaggctgagt cctggtaccg tagcaagtgt
1021 gaggagatga aggccacggt gatcaggcat ggggagaccc tgcgccgcac caaggaggag
1081 atcaacgagc tgaaccgcat gatccagagg ctgacggccg agattgagaa tgccaagtgc
1141 cagcgtgcca agctggaggc tgctgtggct gaggcagagc agcagggtga ggcggccctc
1201 agcgatgccc gctgcaagct ggctgagctg gagggcgccc tgcagaaggc caagcaggac
1261 atggcctgcc tgctcaagga gtaccaggag gtgatgaact ccaagctggg cctggacatc
1321 gagatcgcca cctacaggcg cctgctggag ggcgaggaac acaggctgtg tgaaggtgtg
1381 ggctctgtga atgtctgtgt cagcagctcc cgtggtggag tctcctgtgg gggcctctcc
1441 tacagcacca ccccagggcg ccagatcact tctggcccct cagccatagg cggcagcatc
1501 acggtggtgg cccctgactc ctgtgccccc tgccagcctc gttcctccag cttcagctgc
1561 gggagtagcc ggtcggtccg ctttgcctag tagagtcatg gagccagggc ttcctgccaa
1621 gcacctgcct gcctgcatca ctgcactgaa tggcatgtga atggaaaatg tgtgcttgct
1681 tccagaatct tctggatgtt cctacagagg ggaagaccta cagagggaaa gaccctcggg
1741 ccgctcccct gcgccttttc atgctaggga gatgcatcct agttgtcctc ctggcagctg
1801 ttttcagagg cattcccagc ccttcactta actcctactt agctccaaaa tacctgtatc
1861 caatttgtat tattccccca gctctcaggg acaagaccag tcccccagcg tggtggtcag
1921 cacggaagct ccaccttctg ggtggaggcg ccatcctaac catccagcca ggccacccac
1981 aacccgagaa tcagggagaa agtccctccc cagcagcccc ctcctcctgg ctgggaagaa
2041 tggtccccca gcaagcactt gcctgttcat tcccgttcat gttttgcttc tctctcagac
2101 tgccttcctg cttctgggct aacctgttcc agccaggctc ctcatgtgac ctcgcagttg
2161 agaagcccat tatcgtgggg catccttttg cctacagccc ctggttaggg cactttggac
2221 aggtcttgct attcagtgaa cctttgtaca tttcaaagaa gactccatgg ctgctccaga
2281 tgcccccttg ctgggtgcag gtggggactg tccaatgcag agctggcggg acagagagtt
2341 aagccacttc ctgggtctcc ttcttatgac tgtctatggg tgcattgcct tctgggttgt
2401 ctcgatctgt gtttcaataa atgccgctgc aatgcaaaaa aaaaaaaaaa aaaa
//