LOCUS X97675 4237 bp mRNA linear HUM 09-SEP-2004
DEFINITION H.sapiens mRNA for plakophilin 2a and b.
ACCESSION X97675
VERSION X97675.1
KEYWORDS plakophilin 2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Mertens C., Kuhn C., Franke W.W.
TITLE Plakophilins 2a and 2b: constitutive proteins of dual location in
the karyoplasm and the desmosomal plaque
JOURNAL J. Cell Biol. 135(4), 1009-1025(1996).
PUBMED 8922383
REFERENCE 2
AUTHORS Mertens C.
JOURNAL Submitted (29-APR-1996) to the INSDC. C. Mertens, German Cancer
Research Center, Cellbiology, Im Neuenheimer Feld 280, Heidelberg,
69120, FRG
REMARK Revised by [3]
REFERENCE 3 (bases 1 to 4237)
AUTHORS Mertens C.
JOURNAL Submitted (09-JAN-1997) to the INSDC. C. Mertens, German Cancer
Research Center, Cellbiology, Im Neuenheimer Feld 280, Heidelberg,
69120, FRG
FEATURES Location/Qualifiers
source 1..4237
/db_xref="H-InvDB:HIT000325014"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..>4237
CDS 26..2671
/product="plakophilin 2b"
/db_xref="GOA:Q99959"
/db_xref="H-InvDB:HIT000325014.15"
/db_xref="HGNC:HGNC:9024"
/db_xref="InterPro:IPR000225"
/db_xref="InterPro:IPR016024"
/db_xref="InterPro:IPR028435"
/db_xref="PDB:3TT9"
/db_xref="UniProtKB/Swiss-Prot:Q99959"
/protein_id="CAA66264.1"
/translation="MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSS
GRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRS
PVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAH
YTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYH
RQYQHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVP
LQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLT
ERSTFTDSQLGNADMEMTLERAVSMLEADHMPPSRISAAATFIQHECFQKSEARKRVN
QLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTR
DLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWN
LSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMS
SAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPE
KYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIV
IRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHV
GDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYT
LNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHA
YKKAQFKKTDFVNSRTAKAYHSLKD"
CDS join(26..1402,1535..2671)
/product="plakophilin 2a"
/db_xref="GOA:Q99959"
/db_xref="HGNC:HGNC:9024"
/db_xref="InterPro:IPR000225"
/db_xref="InterPro:IPR016024"
/db_xref="InterPro:IPR028435"
/db_xref="PDB:3TT9"
/db_xref="UniProtKB/Swiss-Prot:Q99959"
/protein_id="CAA66265.1"
/translation="MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSS
GRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRS
PVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAH
YTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYH
RQYQHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVP
LQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLT
ERSTFTDSQLGNADMEMTLERAVSMLEADHMPPSRISAAATFIQHECFQKSEARKRVN
QLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTR
DLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDF
DIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCI
LHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEK
SNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQ
KESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPS
TDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASV
LLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD"
BASE COUNT 1234 a 1005 c 976 g 1022 t
ORIGIN
1 cagctcggtc gcccccaccg gccccatggc agcccccggc gccccagctg agtacggcta
61 catccggacc gtcctgggcc agcagatcct gggacaactg gacagctcca gcctggcgct
121 gccctccgag gccaagctga agctggcggg gagcagcggc cgcggcggcc agacagtcaa
181 gagcctgcgg atccaggagc aggtgcagca gaccctcgcc cggaagggcc gcagctccgt
241 gggcaacgga aatcttcacc gaaccagcag tgttcctgag tatgtctaca acctacactt
301 ggttgaaaat gattttgttg gaggccgttc ccctgttcct aaaacctatg acatgctaaa
361 ggctggcaca actgccactt atgaaggtcg ctggggaaga ggaacagcac agtacagctc
421 ccagaagtcc gtggaagaaa ggtccttgag gcatcctctg aggagactgg agatttctcc
481 tgacagcagc ccggagaggg ctcactacac gcacagcgat taccagtaca gccagagaag
541 ccaggctggg cacaccctgc accaccaaga aagcaggcgg gccgccctcc tagtgccacc
601 gagatatgct cgttccgaga tcgtgggggt cagccgtgct ggcaccacaa gcaggcagcg
661 ccactttgac acataccaca gacagtacca gcatggctct gttagcgaca ccgtttttga
721 cagcatccct gccaacccgg ccctgctcac gtaccccagg ccagggacca gccgcagcat
781 gggcaacctc ttggagaagg agaactacct gacggcaggg ctcactgtcg ggcaggtcag
841 gccgctggtg cccctgcagc ccgtcactca gaacagggct tccaggtcct cctggcatca
901 gagctccttc cacagcaccc gcacgctgag ggaagctggg cccagtgtcg ccgtggattc
961 cagcgggagg agagcgcact tgactgtcgg ccaggcggcc gcagggggaa gtgggaatct
1021 gctcactgag agaagcactt tcactgactc ccagctgggg aatgcagaca tggagatgac
1081 tctggagcga gcagtgagta tgctcgaggc agaccacatg ccgccatcca ggatttctgc
1141 tgcagctact ttcatacagc acgagtgctt ccagaaatct gaagctcgga agagggttaa
1201 ccagcttcgt ggcatcctca agcttctgca gctcctaaaa gttcagaatg aagacgttca
1261 gcgagctgtg tgtggggcct tgagaaactt agtatttgaa gacaatgaca acaaattgga
1321 ggtggctgaa ctaaatgggg tacctcggct gctccaggtg ctgaagcaaa ccagagactt
1381 ggagactaaa aaacaaataa cagaccatac agtcaattta agaagtagga atggctggcc
1441 gggcgcggtg gctcacgcct gtaatcccag cactttggga ggccaaggcg ggcggatcac
1501 gaggtcagga gttcgagacc agcctgacca acatggtttg ctgtggaatt tgtcatctaa
1561 tgacaaactc aagaatctca tgataacaga agcattgctt acgctgacgg agaatatcat
1621 catccccttt tctgggtggc ctgaaggaga ctacccaaaa gcaaatggtt tgctcgattt
1681 tgacatattc tacaacgtca ctggatgcct aagaaacatg agttctgctg gcgctgatgg
1741 gagaaaagcg atgagaagat gtgacggact cattgactca ctggtccatt atgtcagagg
1801 aaccattgca gattaccagc cagatgacaa ggccacggag aattgtgtgt gcattcttca
1861 taacctctcc taccagctgg aggcagagct cccagagaaa tattcccaga atatctatat
1921 tcaaaaccgg aatatccaga ctgacaacaa caaaagtatt ggatgttttg gcagtcgaag
1981 caggaaagta aaagagcaat accaggacgt gccgatgccg gaggaaaaga gcaaccccaa
2041 gggcgtggag tggctgtggc attccattgt tataaggatg tatctgtcct tgatcgccaa
2101 aagtgtccgc aactacacac aagaagcatc cttaggagct ctgcagaacc tcacggccgg
2161 aagtggacca atgccgacat cagtggctca gacagttgtc cagaaggaaa gtggcctgca
2221 gcacacccga aagatgctgc atgttggtga cccaagtgtg aaaaagacag ccatctcgct
2281 gctgaggaat ctgtcccgga atctttctct gcagaatgaa attgccaaag aaactctccc
2341 tgatttggtt tccatcattc ctgacacagt cccgagtact gaccttctca ttgaaactac
2401 agcctctgcc tgttacacat tgaacaacat aatccaaaac agttaccaga atgcacgcga
2461 ccttctaaac accgggggca tccagaaaat tatggccatt agtgcaggcg atgcctatgc
2521 ctccaacaaa gcaagtaaag ctgcttccgt ccttctgtat tctctgtggg cacacacgga
2581 actgcatcat gcctacaaga aggctcagtt taagaagaca gattttgtca acagccggac
2641 tgccaaagcc taccactccc ttaaagactg aggaaaatga caaagtattc tcggctgcaa
2701 aaatccccaa aggaaaacac ctatttttct actacccagc ccaagaaacc tcaaaagcat
2761 gccttgtttc tatctttctc tatttccgtg gtcccctgaa tccagaaaac aaatagaaca
2821 taattttatg agtcttccag aagacctttg caagtttgcc accagtagat accggccaca
2881 ggctcgacaa atagtggtct ttgttattag ggcttatggt agatggcttc ctggaatcaa
2941 aatgtgaatt catgtggaag ggacattaat ccaataaata aggaaagaag ctgttgcatt
3001 actgggattt taaaagtttg atttacattt atattccttt tctggttccc atgttttgtc
3061 actcatgtgc acattgcttc gccattgggc ctccagtgta ttgttctgca gtgttgaaac
3121 agaatggaaa tgacaagaaa tatctgcagt tatccaggag aaagtataat ggcaaaatta
3181 ttggtttctt tctttacttt gtgcttgttt ttatcccctt ggttgttttt ctctgatttt
3241 taaataaact taagaaattt agattacaga gtatgcatga ctgtaagaaa aagaaattga
3301 gaggaagtga tcatagcaaa ttaaagaagt cttttcctcc cagaacttaa agtaaaataa
3361 aaaataaata aataaataaa atcttttcca cagagaaagg caactgtgat gataaaattt
3421 aagctccccc aacactgagt caatgagatt tttctcagga gatactttac ctataacaac
3481 gccgttaaat ccaaatctct tctaaacgat ggcattctat gtaatgcctt tcctggactt
3541 ttttggccac tgcctggact agtgaaagaa tggactctat ctttatctgc aagaggaact
3601 aaggccttct atcagactgc ctggccagcc tggggcactg aaaatacggc tcatgttaat
3661 gagttacatt atcagccagc ccagccttgc ccaccattta agaaatatca cagagccact
3721 agatctcata tgatcttctt caagccatta ttttaactca agaaaactct agagaagaaa
3781 agtgaagaag tcatgttgaa gaagatgtaa gaatgtgtca agaccatcca gaaatgatat
3841 gagaaatact gatattttaa atggttgaca tcatccagcg aaatgaatct acattaaatg
3901 ttgttttaac tgcgctatga ttaaaaccat tcatatagag ttagtcttta caactactat
3961 tctgttattt ttttttttaa tctgacaaca tttgtcctaa gtaagataag caaaaaaatt
4021 cttcaactcc ttttggcaag aaaactgtaa cagaaaataa attttgaatg tgtacttaag
4081 tctttattat atttgaagca attttttttc aattttaaaa gctgaatgaa gacaacttag
4141 gttgctaacc tagttcaaaa tgaaattatt tagataccaa tttttaaaat actggagaga
4201 atttatatgt ctttttccag agttctgatg ataagca
//