LOCUS X96783 6471 bp DNA linear HUM 14-NOV-2006
DEFINITION H.sapiens Syt V gene (genomic and cDNA sequence).
ACCESSION X96783
VERSION X96783.1
KEYWORDS synaptotagmin V; sytV gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Craxton M.A., Olsen A., Goedert M.
TITLE Human synaptotagmin V (SYT5): sequence, genomic structure, and
chromosomal location
JOURNAL Genomics 42(1), 165-169(1997).
PUBMED 9177789
REFERENCE 2 (bases 1 to 6471)
AUTHORS Craxton M.A.
JOURNAL Submitted (22-MAR-1996) to the INSDC. M.A. Craxton, MRC Lab. of
Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
COMMENT Locations of clones:
Clone hs10 (cDNA) 1 (6001) Clone mp2 (cDNA) 462 (6471)
Clone 163Pst60 479 1179 Clone 36Bam65 699 2438
Clone 36Eco71 1767 2926 Clone 1917PE20 2921 3510
Clone Sac9 3505 3847 Clone Sac3 3842 4313
Clone 710S12 4308 5037 Clone 710S3 5032 5766
Clone 2113MS15 5761 6011
FEATURES Location/Qualifiers
source 1..478
/organism="Homo sapiens"
/mol_type="genomic DNA"
/dev_stage="adult"
/clone="hs10"
/clone="mp2"
/tissue_type="brain"
/db_xref="taxon:9606"
source 479..6471
/organism="Homo sapiens"
/chromosome="19"
/mol_type="genomic DNA"
/dev_stage="adult"
/clone="36Bam65"
/clone="36Eco71"
/clone="1917PE20"
/clone="Sac9"
/clone="Sac3"
/clone="710S12"
/clone="710S3"
/clone="2113MS15"
/clone="163Pst60"
/tissue_type="brain"
/db_xref="taxon:9606"
mRNA join(1..587,1180..1352,3424..3543,3672..3839,4207..4374,
4547..4664,4896..5029,5888..6471)
/gene="Syt V"
exon 1..587
/number=1
variation 236..238
/replace="cg"
/note="clone hs10"
CDS join(509..587,1180..1352,3424..3543,3672..3839,4207..4374,
4547..4664,4896..5029,5888..6088)
/gene="Syt V"
/product="synaptotagmin V"
/db_xref="GOA:O00445"
/db_xref="HGNC:HGNC:11513"
/db_xref="InterPro:IPR000008"
/db_xref="InterPro:IPR001565"
/db_xref="InterPro:IPR028689"
/db_xref="InterPro:IPR035892"
/db_xref="PDB:5H4Y"
/db_xref="PDB:5H4Z"
/db_xref="UniProtKB/Swiss-Prot:O00445"
/protein_id="CAA65579.1"
/translation="MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIF
SCCFCLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQ
VXDKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLXDKRRRY
ETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVD
LGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSD
PYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKL
GKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP"
intron 588..1179
/number=1
variation 718..720
/replace="tg"
/note="clone 163Pst60"
variation 765..768
/replace="ca"
/note="clone 36Bam65"
variation 981
/replace="t"
/note="clone 36Bam65"
variation 981
/replace="c"
/note="clone 163pst60"
exon 1180..1352
/number=2
variation 1208
/replace="a"
/note="clone hs10"
variation 1208
/replace="g"
/note="clone 36Bam65"
variation 1208
/replace="g"
/note="clone mp2"
intron 1353..3423
/number=2
repeat_region 1694..1981
/rpt_family="Alu"
variation 1829
/replace="g"
/note="clone 36Eco71"
variation 1829
/replace="a"
/note="clone 36Bam65"
variation 2040
/replace="c"
/note="clone 36Bam65"
variation 2040
/replace="t"
/note="clone 36Eco71"
variation 2073
/replace="g"
/note="clone 36Bam65"
variation 2073
/replace="a"
/note="clone 36Eco71"
variation 2198
/replace="t"
/note="clone 36Eco71"
variation 2198
/replace="a"
/note="clone 36Bam65"
variation 2238
/replace="c"
/note="clone 36Bam65"
variation 2238
/replace="t"
/note="clone 36Eco71"
exon 3424..3543
/number=3
variation 3481
/replace="c"
/note="clone mp2"
variation 3481
/replace="g"
/note="clone 1917PE20"
variation 3481
/replace="g"
/note="clone hs10"
intron 3544..3671
/number=3
exon 3672..3839
/number=4
variation 3759
/replace="a"
/note="clone hs10"
variation 3759
/replace="c"
/note="clone Sac9"
variation 3759
/replace="c"
/note="clone mp2"
intron 3840..4206
/number=4
exon 4207..4374
/number=5
variation 4209
/replace="c"
/note="clone mp2"
variation 4209
/replace="c"
/note="clone hs10"
variation 4209
/replace="a"
/note="clone Sac3"
intron 4375..4546
/number=5
variation 4546..4550
/replace="gg"
/note="clone hs10"
exon 4547..4664
/number=6
intron 4665..4895
/number=6
exon 4896..5029
/number=7
intron 5030..5887
/number=7
repeat_region 5163..5188
repeat_region 5237..5494
exon 5888..6471
/number=8
BASE COUNT 1437 a 1890 c 1806 g 1328 t
ORIGIN
1 ggcccaggca ccggtgggcc ccggagcgag cctgccccgc cgggactccg cgtctgtgcg
61 tcagccccgc ccgttgtcct ggcaacaacc cgttgcccgg gcaaccagct ttgctcttac
121 cccgcttgag aggagcccgg ctgttgctct gggcaacgcg gtctgctggt tcccacgtct
181 gccttcgccc gcttccggtt cagaccctgc ggaggggcga ggacgaggca gaagtcagcg
241 ggatgcctgt ggggccgtgg aggaagaggg tatcccttta ggatggaact aggtcctgga
301 caccccctct caagtgcggg gaggctgata ctacaactcc cagcatgact cgcggtggct
361 gtccggtttc tgcgcggctg ttcgcgcaaa ggcctcatgg gagttggagt tctttgttgt
421 gcgtggggct caaaggacgt ctggggtggg aatgggggac tagggtgctt gagtgtctct
481 gcagaaaaga ctccaggacc ccgccaccat gttcccggag cccccaaccc cggggcctcc
541 atcgcccgac acgcctcccg actccagtcg catcagccac ggcccaggtg agcaagaccc
601 gggggtgggg ggccgagcag agagaaagcc tggccaggat tccgaggggc gggattcgga
661 cgggtgtact cgggcaggcg ggctggaaaa tccggctggg atcccgggtc gtcatcctgg
721 actggaatgc gaacgaaatg gggtaaaagg aaggaacaga tttgcaaaaa aaaaaaaaaa
781 aaaaaaaaaa aaaatcgaaa ccggatcaag gggtgttgca tggaatggga tcttagaatt
841 ggaaggtcca cctagctctt cttttacaga taaggaaaca ggcccgatga ggagcagggc
901 ttcttgtaaa agcatcagga gttgagcaga aatggggggc ggggtcgggt aaggaaaggc
961 agaactaaca agcaagcaaa yccagatggt gtcagcctgg gttggggcat cgaatctctc
1021 tataggccac attaggtgga agaaaaacac aggaagaaat gcaatgaaaa tggctggagg
1081 gaaaaggagg ccagcattcc agcttccacg tgtaatcagg actgaatcag cctgcgtgct
1141 gcccaggcct caatgtgtgt tgtctccacc cctctgcagt gcccccctgg gccctggcca
1201 ccatcgtrct ggtctcaggc ctcctcatct tcagctgctg tttctgtctc taccggaaga
1261 gctgtcggag gcggacaggc aagaagagcc aggcccaagc ccaggtccac cttcaggaag
1321 tgaaggggct gggccagagt tacatagaca aggtgtggcc cagcccagcc cctccacctg
1381 gccccttccc gcaccctgct cctctcaatg gcccagctgg tcccagtccc tgctcccttc
1441 tgtcctatag gaacccacct tactggctca tcctccctgt gtgtctagcc ctcaactgga
1501 ctctggggac ccagagatgg aacagaacta gttgctattc ccaagaactt cccagtctgg
1561 tgggagagtc aggcactgac acagacactc accacacagg gtaatatgtg ccatactaca
1621 gggtctcata ggagcacaga aaaggcatcc cactgtatag aaacctacag aaacatataa
1681 atatttggct ctgggccggg tgcggtggct cacgcctgta atcctagcac ttgggaggct
1741 gaggtggaca gattgcctga ggtcatgaat tcaagactag cctgggcaac atgatgaaac
1801 cctgtctcta ctaaaaatac aaaagccarc catggtggtg tggtataatc ccagctactc
1861 gagaggctga ggcactgaaa ccgggaggtg gaggctgcag tgagctgtga tcgcgccact
1921 gcactccagc ctgggtgaca gagcgagact ctgtctccaa taaatagata aataaataaa
1981 tggctctgaa agctgaaaac cagctttgtg ccagaatact ttaaaatatg ctgattttty
2041 tcagaaaatg ggacatattt acagtaggaa aargtttaaa acagagggtc agacagagga
2101 ggcttcgtgg tggaggtgac ttctgcactg agacctgagg gacagagtta actgagacca
2161 gagagaagga cattctagtc caagttggag catgtgtwga ggccccatat ccagattcag
2221 gccccatatc cagattcyga ggcttatttg gggaacaaag agtcatttct cacaatagct
2281 gcactctgga gtgaagtgtc tggagaactc agcagtatcc atgtcatgaa ggtgatgaag
2341 gctacaaata tgttttgagc atgagaggga cagggtcaga tggtgttagg atgactcctc
2401 tggaaccctg tgtaggacag atctgcggcg agggatccag ggacgaggcc agtgcagcag
2461 cagcctggag aggataaaag acatttgcat tggatgaggc cgttggaatg gaaagtggtc
2521 actgcagggt ctgaaaatta agtctctcag tgcagagtgc agtggttgcc tgggagccag
2581 acagccctag gtttccaacc aagaaggacc atttcctggt tgtgtgacct tggagaactc
2641 actgtccctc tctgagcctc aagtctgtgg tcactaactt ggtatttccc ctccttcctt
2701 ctcaataagg agctgttcaa ttagcatccg taaaggatgc tatttagggt cctggtgtcc
2761 agccccatcc ctgtccctta aaccagtgat gttcaaagac cgtctgcagc agaatcacac
2821 tgggtacttg ttgaaatgca aattctggca ctagcacctg acctatcaag tcagaatccc
2881 tgaagaggtg acctcagaca ttttgccaca ggattcaggg gaattcaggt tcacattgaa
2941 ttttaagaat tgctggccta ggttaaggag acaccttctg ctttttcatt caactttaga
3001 atggcaagta cacagtaaat atgccatttc tcctccatgt tttgctgtgc taagatcaca
3061 agtaaacatg gcagtttgga ctagcacccc agtacatcca ttagcatgtg aaataaaacc
3121 tgcattattc ctgtgggcaa tgggacacta tcagcacttg ttttaatcta agcatgacaa
3181 gcacatgtct agttcctgcc catagcagac accactaatc aaaccttcac aaacatactg
3241 catctgtgtt accacgtcta tttcctgcct gtggcagaca gcactagtca aatactgaat
3301 ctgcttagcc tgtgagagct caggtatagc ccaagggacc tgtgagcctc ccttggcttc
3361 tgagcctgat ggatactgct atcaggggaa gacttcaccc acccttaccc ctggctcctt
3421 aaggtgcagc cagaagtaga ggagctggag ccagcaccat ccgggccagg gcagcaggtg
3481 scagacaagc atgagctagg acgactgcag tactccctgg attatgactt ccagagtggc
3541 caggtgggtg tggaggaagg ggaagctttg gagggaggat cccgggggtt ccaacccctt
3601 ctgaaaggag ccatggaagg gaggctaaga ctagtgttcc ccacctcccc cactgtgcct
3661 gggccctgca gctgctggtg ggcattctgc aagcaatggg attggcagcc ttggatcttg
3721 gtggctcctc ggacccctat gtgcgggtct acctgctgmc ggacaaacgg aggcggtacg
3781 agaccaaggt gcatcggcag acgctgaacc ctcactttgg ggagaccttc gccttcaagg
3841 tgagctctgc ttcaggcccc gtgttccata gcctgtgccc agtccctgga acactaggga
3901 ccgacccctt ccgcttttcc tggaggcagc cacagctcag gtggcagcta ccagctctgg
3961 ggctattcca ctggaccctg ggcactactg actcctgggc tgtagcctgg tccttgggcg
4021 gtacgatttg ggttccactg acccgtgatt tttttccgca tggatccctg gactttccca
4081 tttgagttcc cccaactgtt cgcttcgacc ctcgctgcct cactccacgc cttccttctg
4141 gttgtgctgt gcctcaccct atctctgact tcctgctctc tactgcggat tctctgtgca
4201 ctccaggtmc cctacgtgga gctggggggc agggtgctgg tcatggcggt gtacgacttc
4261 gaccgcttct ctcgcaatga cgccatcggg gaggtgcggg tccctatgag ctccgtggac
4321 ctggggcggc cagtgcaggc ctggcgggag ctgcaggcgg ctccgcggga ggaggtgagc
4381 atgcgcggtc gcgccccgag ccacgccccc aggcccagtc ccgcccacaa catcctgagc
4441 caatcagatc ataggctttc cagaccctca gggcggcgtg gattgtaccc ctgaggaggc
4501 atggatgtgg agccggggct ctggtgatgg gcccctctcc tttcagcagg agaagcttgg
4561 ggacatctgc ttctccctcc gctatgtccc cacggccggg aagctcaccg tcatcgtcct
4621 ggaggctaaa aacctgaaga agatggacgt aggaggactg tcaggtgtgt gggaagcaag
4681 ggagtggggt gtgaggggat ggcgtggggt gggttctcgt tctgacagtt tctgagcctc
4741 gagggtttct tcggggacag ggaggacctg gctgctgtgg aaggcatgga ttttggcata
4801 gagctaggga gacccgaagg gtgtaggcag tgtttctatg ttggtccaac aacccagcag
4861 tggggagcta taagactcct ccttcctctc cccagatcca tacgtcaagg tccacctgct
4921 gcagggcggc aaaaaggtgc ggaagaagaa aaccaccatc aagaagaaca ctctgaaccc
4981 ctattacaac gaagctttca gcttcgaggt gccctgtgac caagtccagg tgagctcaaa
5041 cctgcccttc tccaagagcc cagaccttta gtaatcgcca ttgctaggcg gagggagact
5101 ttttagcatc tccctagaaa ccaggtgagg gggtctgagg ttatgctctc agtctgtttc
5161 ctcctatgag gaccaggaag cctcttccac tccaggaaga gactccttaa aattgggtgt
5221 gggtgtccta tctgctctaa gcgggaccgg gatgctccac ccctaagcgg aaccaggatg
5281 tcccacccct aagcagtacc agatgctcca ccctaagcag gatcagtatg ccccgcccca
5341 ccaagcggaa ccaggatgct ccgcccccaa gcaggaccag gatgccccgc ccccaagcag
5401 gaccaggatg ccccgccccc aagcgggacc aggatgcccc actcctaagc gggaccagat
5461 tccccaccct aagcaggacc aggatgcccc gccctcctca ggaacgtggt tctaagaaaa
5521 agagacctcc cctcacttct ttagggacgg cgcctaccct agcccggccc ctgttaaagt
5581 tctgcagctt tgcggctctt aggaggctgc tcccccagga ggcgccgaac acacccgctc
5641 cgcaaccgag tcctgagggt tcatttcctt agaaacctgg ctgcgcagga agaaaggcgc
5701 cagagcctcc tcctcgccgc aggctccgtc cctctcgtct cccaccccct cccccgtccc
5761 gagctccggg gccccgagcc ctcgggtggc agcgagaggt accctcagcc gtgaaaacgg
5821 acaccgcccc ttccggggcc tcctcccctc acgctcctct ctcctcttcc tcccgcgccc
5881 accccagaag gtgcaggtgg agctgaccgt gctggactac gacaagctgg gcaagaacga
5941 ggccatcggg agggtggccg tgggggcggc cgccggcggg gctggcctgc ggcactgggc
6001 ggacatgctg gccaacccgc ggcggcccat tgcccagtgg cactcgctgc ggcccccgga
6061 ccgagtgagg ctgctgcctg cgccctgact cccaccccaa gcccccggcc aagcctggac
6121 tctagcccct gaccccagac tcccgagacc ggccaaagcc aagccagccc cacccttaag
6181 cttcctctga cggttaccct ccccccacct tccaccccaa ccatctgaac cattcctgtc
6241 ttctcacccc caacgatgcc aatcacgaca actttccagc acactccccc gaccctcgcg
6301 gacacaccca gatgccccag ggaccccggg aagggaaggc agcctggttt ctcctgcccc
6361 cgggtcctgc cccctgcttt gacaatcagc catcctcgtc tgctctcctc tctcttccaa
6421 cacagcccat ccctgcactg ctcctgaggc caaataaata ttcagcagct c
//