LOCUS X95712 4389 bp mRNA linear HUM 21-OCT-2008
DEFINITION H.sapiens mRNA for receptor protein tyrosine phosphatase.
ACCESSION X95712
VERSION X95712.1
KEYWORDS fmi gene; FMI protein; receptor protein tyrosine phosphatase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Crossland S., Smith P.D., Crompton M.R.
TITLE Molecular cloning and characterization of PTP pi, a novel
receptor-like protein-tyrosine phosphatase
JOURNAL Biochem. J. 319, 249-254(1996).
PUBMED 8870675
REFERENCE 2 (bases 1 to 4389)
AUTHORS Crossland S.
JOURNAL Submitted (15-FEB-1996) to the INSDC. S. Crossland, Institute of
Cancer Research, Haddow Labs, 15 Cotswold Rd, Sutton, Surrey SM2
5NG, UK
FEATURES Location/Qualifiers
source 1..4389
/db_xref="H-InvDB:HIT000324929"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda ZAP II"
/clone="MCF7-fmi"
/cell_line="MCF-7"
/cell_type="carcinoma"
/tissue_type="mammary"
/db_xref="taxon:9606"
CDS 61..4389
/gene="fmi"
/product="FMI protein"
/note="receptor protein tyrosine phosphatase"
/db_xref="GOA:Q92729"
/db_xref="H-InvDB:HIT000324929.13"
/db_xref="HGNC:HGNC:9683"
/db_xref="InterPro:IPR000242"
/db_xref="InterPro:IPR000387"
/db_xref="InterPro:IPR000998"
/db_xref="InterPro:IPR003595"
/db_xref="InterPro:IPR003961"
/db_xref="InterPro:IPR013320"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR016130"
/db_xref="InterPro:IPR029021"
/db_xref="InterPro:IPR036116"
/db_xref="InterPro:IPR036179"
/db_xref="UniProtKB/Swiss-Prot:Q92729"
/protein_id="CAA65016.1"
/translation="MGGDAPTMARAQALVLELTFQLCAPETETPEVGCTFEEGSDPAV
PCEYSQAQYDDFQWDPGSPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQF
SYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQV
LFEALISPDRRGYMGLDDICILSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAEA
ERFLLQRQSGALVPAAGVRHISHRSFLATFPLAAVSRAEQDLYRCVSQAPRGRGTSLN
FAEFMVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEV
HAVSLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRLGPPFISRTKCAEPMRAPKGLAF
AEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLGSSHNQTIPRVCEDRARCQPLHH
EEPAALSERSREVVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWE
EPQEPNGLITQYEISYQSIESSDPAVNVQATSTISKLRNETYHVFSNLHPGTTYLFSV
GARTGKGFGQAALTEITTYISAPSLDYADMPSPLGESENNITVLLRPAQGRGAPISVY
QVIVEEEQGSRRLRREPGGQDCFPVPLTFEAALARGLVDYFGAELAASSLPEAMPFTV
GDNKTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQ
RSEEMGLILGICAGGLAVLILLLGAIIVIIRKGRDHYAYSYYPKPVNMTKATVNYRQE
KTHMMSAVDRSFTDQSTLQPPGLSFMDTHGYSTRGEQRSGGVTEASSLLGGSPRRPCG
RKGSPYHTVQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKVKGS
RQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRM
VWQEHCSSIVMITKLVEVAGCKCSRYWPEDSDTYGDIKIMLVKTETLAEYVVRTFALE
RRGYSARYEVRQFHFTAWPEHGVPYHTTGLLAFIRRVKASTPPDAGPIVIHCSAGTGR
TGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRCVNMIQTEEQYIFIHDAILEACLCGE
TTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEEYSIALLPRNRDKN
RSMDVLPPDRCLPFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLV
YDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRV
QNISRLQEGHLLVRHFQFLRWSAYRDTPDSEKAFLHLLAEVDKWQAESGDGRTIVHCL
NGGGRRGTSCALRTVLEMIRCHNLVDVSFAAKTLRNYKPNMVETMDQYHFCYDVALEY
LEAGVR"
misc_feature 931..2085
/note="fibronectin repeats"
BASE COUNT 899 a 1382 c 1306 g 802 t
ORIGIN
1 cggatcgcct cgggttgggc tcgggctccg gggggggtgt cccccgtgcc gggtcccggt
61 atgggtgggg acgctccaac catggcccgt gcccaggcgc tcgtgttgga actcaccttc
121 cagctctgcg cgccggagac cgagactccg gaagttggtt gcaccttcga ggagggaagt
181 gacccagcag tgccctgcga gtacagccag gcccagtacg atgacttcca gtgggacccg
241 ggctcacctg cggacctgcc ccacggctcc tacttgatgg tcaacacttc ccagcatgcc
301 ccaggccagc gagcccatgt catcttccag agcctgagcg agaatgatac ccactgtgtg
361 cagttcagct acttcctgta cagccgggac gggcacagcc cgggcaccct gggcgtctac
421 gtgcgcgtta atgggggccc cctgggcagt gctgtgtgga atatgactgg atcccacggc
481 cgtcagtggc accaggctga gctggctgtc agcactttct ggcccaatga atatcaagtg
541 ctgtttgagg ccctcatctc cccagaccgc aggggctaca tgggcctaga tgacatctgc
601 attctcagct acccctgcgc aaaggcccca cacttctccc gcctgggcga cgtggaggtc
661 aacgcgggcc agaacgcgtc gttccagtgc atggccgcgg gcagagccga ggccgaacgc
721 ttcctcttgc aacggcagag cggggcgctg gtgccggcgg cgggcgtgcg gcacatcagc
781 caccgcagct tcctggccac tttcccgctg gctgccgtga gccgcgccga gcaggacctg
841 taccgctgtg tgtcccaggc cccgcgcgga cgcgggacgt ctctcaactt cgcggagttt
901 atggtcaagg agcccccaac tcccatcgcg cccccacagc tgctgcgtgc tggccccacc
961 tacctcatca tccagctcaa caccaactcc atcattggcg acgggccgat cgtgcgcaag
1021 gagattgagt accgcatggc gcgcgggccc tgggctgagg tgcacgccgt cagcctgcag
1081 acctacaagc tgtggcacct cgaccccgac acagagtatg agatcagcgt gctgctcacg
1141 cgtcccggag acggcggcac tggccgcctt gggccaccct tcatcagccg caccaaatgc
1201 gcagagccca tgagggcccc caaaggcctg gcttttgctg agatccaggc ccgtcagctg
1261 accctgcagt gggaaccact gggctacaac gtgacgcgtt gccacaccta tactgtgtcg
1321 ctgtgctatc actacaccct gggcagcagc cacaaccaga ccataccgag agtgtgtgaa
1381 gacagagcaa ggtgtcagcc gctacaccat gaagaacctg ctgccctatc ggaacgttca
1441 cgtgaggttg tcctcactaa ccctgagggg cgcaaagagg gcaaggaggt cactttccag
1501 acggatgagg atgtgcccag tgggattgca gccgagtccc tgaccttcac tccactggag
1561 gacatgatct tcctcaagtg ggaggagccc caggagccca atggtctcat cacccagtat
1621 gagatcagct accagagcat cgagtcatca gacccggcag tgaacgtgca ggccacgagt
1681 accatctcca agctccgcaa tgagacctac catgtcttct ccaacctgca cccaggcacc
1741 acctacctgt tctccgttgg ggcccggaca ggcaaagggt tcggccaggc ggcactcact
1801 gagataacca cttacatctc tgctcccagc ttggattatg ccgacatgcc gtcacccctg
1861 ggcgagtctg agaacaacat caccgtgctg ctgaggccgg cacagggccg cggtgcgccc
1921 atcagtgtgt accaggtgat tgtggaggag gagcagggca gcaggaggct gcggcgggag
1981 ccaggtggac aggactgctt cccagtgcca ttgaccttcg aggcggcgct ggcccgaggg
2041 ctggtggact acttcggggc cgaactggcg gccagcagtc tacctgaggc catgcccttt
2101 accgtgggtg acaacaagac ctaccgaggc ttctggaacc caccacttga gcctaggaag
2161 gcctatctca tctacttcca ggcagcaagc cacctgaagg gggagacccg gctgaattgc
2221 atccgcattg ccaggaaagc tgcctgcaag gaaagcaagc ggcccctgga ggtgtcccag
2281 agatcggagg agatggggct tatcctgggc atctgtgcag gggggcttgc tgtcctcatc
2341 cttctcctgg gtgccatcat tgtcatcatc cgcaaaggga gagaccacta tgcctactcc
2401 tactacccga agccggtgaa catgaccaag gccaccgtca actaccgcca ggagaagaca
2461 cacatgatga gcgccgtgga ccgcagcttc acagaccaga gcaccctgca gccccctggg
2521 ctgtccttca tggacaccca tggctacagc acccggggag aacagcgcag cggtggggtc
2581 actgaggcca gcagcctcct ggggggctcc ccgaggcgtc cctgtggccg gaagggctcc
2641 ccataccaca cggtgcagct gcaccctgcg gtgcgtgtcg cagaccttct gcagcacatc
2701 aaccagatga agacggccga gggttacggc ttcaagcagg agtatgagag cttctttgaa
2761 ggctgggacg ccacaaagaa gaaagacaag gtcaagggca gccggcagga gccaatgcct
2821 gcctatgatc ggcaccgagt gaaactgcac ccgatgctgg gagaccccaa tgccgactac
2881 attaatgcca actacataga tggttaccac aggtcaaacc acttcatagc cactcaaggg
2941 ccgaagcctg agatggtcta tgacttctgg cgtatggtgt ggcaggagca ctgttccagc
3001 atcgtcatga tcaccaagct ggtcgaggtg gcagggtgta aatgctcacg gtactggccg
3061 gaggactcag acacctacgg ggacatcaag attatgctgg tgaagacaga gaccctggct
3121 gagtatgtcg tgcgcacttt tgccctggag cggagaggct actctgcccg gtacgaggtc
3181 cgccagttcc acttcacagc gtggccagag catggcgtcc cctaccatac cacggggctg
3241 ctggctttca tccggcgcgt gaaggcctcc accccacctg atgccgggcc cattgtcatc
3301 cactgcagcg cgggcaccgg ccgcacaggt tgctatatcg tcctggatgt gatgctggac
3361 atggcagagt gtgagggcgt cgtggacatt tacaactgtg tgaagactct ctgctcccgg
3421 tgtgtcaaca tgatccagac tgaggagcag tacatcttca ttcatgatgc aatcctggag
3481 gcctgcctgt gtggggagac caccatccct gtcagtgagt tcaaggccac ctacaaggag
3541 atgatccgca ttgatcctca gagtaattcc tcccagctgc gggaagagtt ccagacgctg
3601 aactcggtca cccccccgct ggacgtggag gagtacagca tcgccctgtt gccccggaac
3661 cgcgacaaga accgcagcat ggacgtcctg ccgcccgacc gctgcctgcc cttcctcatc
3721 tccactgatg gggactccaa caactacatt aatgcagccc tgactgacag ctacacacgg
3781 agtgcggcct tcatcgtgac cctgcacccg ctgcagagca ccacgcccga cttctggcgg
3841 ctggtctacg attacgggtg cacctccatc gtcatgctca accagctgaa ccagtccaac
3901 tccgcctggc cctgcctgca gtactggcca gagccaggcc ggcagcaata tggcctcatg
3961 gaggtggagt ttatgtcggg cacagctgat gaagacttag tggctcgagt cttccgggtg
4021 cagaacatct ctcggttgca ggaggggcac ctgctggtgc ggcacttcca gttcctgcgc
4081 tggtctgcat accgggacac acctgactcc gagaaggcct tcttgcacct gctggctgag
4141 gtggacaagt ggcaggccga gagtggggat gggcgcacca tcgtgcactg cctaaacggg
4201 ggaggacgca ggggtacctc ctgcgccctg cggacggtcc tggagatgat ccgctgccac
4261 aacttggtgg acgtttcttt tgctgccaaa accctccgga actacaaacc caacatggtg
4321 gagaccatgg atcagtacca cttttgctac gatgtggccc tggagtactt ggaggctgga
4381 gtaagatag
//