LOCUS X93086 1070 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for biliverdin IX alpha reductase.
ACCESSION X93086
VERSION X93086.1
KEYWORDS biliverdin IX alpha reductase; BVR gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Maines M.D., Polevoda B.V., Huang T.J., McCoubrey JR W.K.
TITLE Human biliverdin IXalpha reductase is a zinc-metalloprotein.
Characterization of purified and Escherichia coli expressed enzymes
JOURNAL Eur. J. Biochem. 235(1-2), 372-381(1996).
PUBMED 8631357
REFERENCE 2 (bases 1 to 1070)
AUTHORS McCoubrey W.K.
JOURNAL Submitted (14-NOV-1995) to the INSDC. W.K. McCoubrey, University of
Rochester, 575 Elmwood Avenue, Rochester, New York 14642, USA
COMMENT Related sequence:-
Maines, M.D. Arch. Biochem. Biophys. 300:320-326 (1995)
FEATURES Location/Qualifiers
source 1..1070
/db_xref="H-InvDB:HIT000324631"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="placental and kidney cDNA (Clontech)"
/clone="hBVR-1"
/db_xref="taxon:9606"
CDS 61..951
/gene="BVR"
/product="biliverdin IX alpha reductase"
/db_xref="GOA:P53004"
/db_xref="H-InvDB:HIT000324631.12"
/db_xref="HGNC:HGNC:1062"
/db_xref="InterPro:IPR000683"
/db_xref="InterPro:IPR015249"
/db_xref="InterPro:IPR017094"
/db_xref="InterPro:IPR036291"
/db_xref="PDB:2H63"
/db_xref="UniProtKB/Swiss-Prot:P53004"
/protein_id="CAA63635.1"
/translation="MNAEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVS
RRELGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTL
SLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTSDPLEED
RFGFPAFSGISRLTWLVSLFGELSLVSATLEERKEDQYMKMTVCLETEKKSPLSWIEE
KGPGLKRNRYLSFHFKSGSLENVPNVGVNKNIFLKDQNIFVQKLLGQFSEKELAAEKK
RILHCLGLAEEIQKYCCSRK"
BASE COUNT 294 a 221 c 305 g 250 t
ORIGIN
1 ggggtggcgc ccggagctgc acggagagcg tgcccgtcag tgaccgaaga agagaccaag
61 atgaatgcag agcccgagag gaagtttggc gtggtggtgg ttggtgttgg ccgagccggc
121 tccgtgcgga tgagggactt gcggaatcca cacccttcct cagcgttcct gaacctgatt
181 ggcttcgtgt cgagaaggga gctcgggagc attgatggag tccagcagat ttctttggag
241 gatgctcttt ccagccaaga ggtggaggtc gcctatatct gcagtgagag ctccagccat
301 gaggactaca tcaggcagtt ccttaatgct ggcaagcacg tccttgtgga ataccccatg
361 acactgtcat tggcggccgc tcaggaactg tgggagctgg ctgagcagaa aggaaaagtc
421 ttgcacgagg agcatgttga actcttgatg gaggaattcg ctttcctgaa aaaagaagtg
481 gtggggaaag acctgctgaa agggtcgctc ctcttcacat ctgacccgtt ggaagaagac
541 cggtttggct tccctgcatt cagcggcatc tctcgactga cctggctggt ctccctcttt
601 ggggagcttt ctcttgtgtc tgccactttg gaagagcgaa aggaagatca gtatatgaaa
661 atgacagtgt gtctggagac agagaagaaa agtccactgt catggattga agaaaaagga
721 cctggtctaa aacgaaacag atatttaagc ttccatttca agtctgggtc cttggagaat
781 gtgccaaatg taggagtgaa taagaacata tttctgaaag atcaaaatat atttgtccag
841 aaactcttgg gccagttctc tgagaaggaa ctggctgctg aaaagaaacg catcctgcac
901 tgcctggggc ttgcagaaga aatccagaaa tattgctgtt caaggaagta agaggaggag
961 gtgatgtagc acttccaaga tggcaccagc atttggttct tctcaagagt tgaccattat
1021 ctctattctt aaaattaaac atgttgggga aacaaaaaaa aaaaaaaaaa
//