LOCUS X92106 1932 bp mRNA linear HUM 24-SEP-2008
DEFINITION H.sapiens mRNA for bleomycin hydrolase.
ACCESSION X92106
VERSION X92106.1
KEYWORDS bleomycin hydrolase; cysteine protease.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Ferrando A.A., Velasco G., Campo E., Lopez-Otin C.
TITLE Cloning and expression analysis of human bleomycin hydrolase, a
cysteine proteinase involved in chemotherapy resistance
JOURNAL Cancer Res. 56(8), 1746-1750(1996).
PUBMED 8620487
REFERENCE 2 (bases 1 to 1932)
AUTHORS Lopez-Otin C.
JOURNAL Submitted (09-OCT-1995) to the INSDC. C. Lopez-Otin, Universidad de
Oviedo, Dept de Biologie Funcional, Area de Bioquimica, Facultad de
Medicina, C/ Julian Claveria S/N, 33006-Oviedo, SPAIN
FEATURES Location/Qualifiers
source 1..1932
/db_xref="H-InvDB:HIT000324545"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="1-1"
/tissue_type="brain"
/db_xref="taxon:9606"
CDS 79..1446
/product="bleomycin hydrolase"
/db_xref="GOA:Q13867"
/db_xref="H-InvDB:HIT000324545.12"
/db_xref="HGNC:HGNC:1059"
/db_xref="InterPro:IPR000169"
/db_xref="InterPro:IPR004134"
/db_xref="InterPro:IPR038765"
/db_xref="PDB:1CB5"
/db_xref="PDB:2CB5"
/db_xref="UniProtKB/Swiss-Prot:Q13867"
/protein_id="CAA63078.1"
/translation="MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRA
TVQRAQHVFQHAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYL
FFWDKVERCYFFLSAFVDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVI
PKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFR
VVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRP
QHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNS
KLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKW
RVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQEPIILPAWDPM
GALAE"
BASE COUNT 536 a 412 c 504 g 480 t
ORIGIN
1 cagcgagccg cagcgcaatc ccggcgctcg cccaaggacc ctggaagcta ccgttacccc
61 gccggcagcg tgggcgccat gagcagctcg ggactgaatt cggagaaggt agctgctctg
121 atacagaaac tgaattccga cccccagttc gtacttgccc agaatgtcgg gaccacccac
181 gacctgctgg acatctgtct gaagcgggcc acggtgcagc gcgcgcagca tgtgttccag
241 cacgccgtgc cccaggaggg caagccaatc accaaccaga agagctcagg gcgatgctgg
301 atcttttctt gtctgaatgt tatgaggctt ccattcatga aaaagttaaa tattgaagaa
361 tttgagttta gccaatctta cctgtttttt tgggacaagg ttgaacgctg ttatttcttc
421 ttgagtgctt ttgtggacac agcccagaga aaggagcctg aggatgggag gctggtgcag
481 tttttgctta tgaaccctgc aaatgatggt ggccaatggg atatgcttgt taatattgtt
541 gaaaaatatg gtgttatccc taagaaatgc ttccctgaat cttatacaac agaggcaacc
601 agaaggatga atgatattct gaatcacaag atgagagaat tctgtatacg actgcggaac
661 ctggtacaca gtggagcaac caaaggagaa atctcggcca cacaggacgt catgatggag
721 gagatattcc gagtggtgtg catctgtttg ggtaatccac cagagacatt cacctgggaa
781 tatcgagaca aagataaaaa ttatcagaaa attggcccca taacaccctt ggagttttac
841 agggaacatg tcaagccact cttcaatatg gaagataaga tttgtttagt gaatgaccct
901 aggccccagc acaagtacaa caaactttac acagtggaat acttaagcaa tatggttggt
961 gggagaaaaa ctctatacaa caaccagccc attgacttcc tgaaaaagat ggttgctgcc
1021 tccatcaaag atggagaggc tgtgtggttt ggctgtgatg ttggaaaaca cttcaatagc
1081 aagctgggcc tcagtgacat gaatctctat gaccatgagt tagtgtttgg tgtctccttg
1141 aagaacatga ataaagcgga gaggctgact tttggtgagt cacttatgac ccacgccatg
1201 accttcactg ctgtctcaga gaaggatgat caggatggtg ctttcacaaa atggagagtg
1261 gagaattcat ggggtgaaga ccatggccac aaaggttacc tgtgcatgac agatgagtgg
1321 ttctctgagt atgtctacga agtggtggtg gacaggaagc atgtccctga agaggtgcta
1381 gctgtgttag agcaggaacc cattatcctg ccagcatggg accccatggg agctttggct
1441 gagtgatact gccctccagc tctttcctcc ttccatggaa cctgacgtag ctgcaaagga
1501 cagatccagg gactgaagcc aaagttatgc aagggactgt gtgttgccac aggacacagt
1561 cagatttcca gtctccacca ggaacctctt cagaaagtgt gctttatgct gaaacagaat
1621 actgttaaag gaaaaaaaag aggggggaag atcaggtcat actatctact ctcctcatct
1681 ctaacagctc aggatctctt agcattttaa ttagatgtaa ttgtttgtct ttaactgtca
1741 aaaagtttgg ttctgtgtct gtgttttaat aagacgagag gacgagcgat tgaggtgtat
1801 ggagagaaaa cagacctaat gctccttgtt cctagagtag agtggaggga gggtggccta
1861 agagttgagc tctcggaact gcatgctgct ggacagtatc actgtctttc ctagatggca
1921 gtcactgaat tc
//