LOCUS X92063 301 bp mRNA linear HUM 17-JUL-1997 DEFINITION H.sapiens mRNA for T cell receptor alpha chain (clone 642). ACCESSION X92063 VERSION X92063.1 KEYWORDS joining region; T cell receptor; T cell receptor alpha chain; variable region. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 301) AUTHORS McIntosh R.S. JOURNAL Submitted (21-SEP-1995) to the INSDC. R.S. McIntosh, Univ. of Sheffield, Dept. of Medicine, Univ.Sheffield Clinical Sciences Centre, Northern General Hospital,Sheffield S5 7AU, UK REFERENCE 2 (bases 1 to 301) AUTHORS McIntosh R.S., Watson P.F., Weetman A.P. TITLE Analysis of the T cell receptor V alpha repertoire in Hashimoto's thyroiditis: evidence for the restricted accumulation of CD8+ T cells in the absence of CD4+ T cell restriction JOURNAL J. Clin. Endocrinol. Metab. 82(4), 1140-1146(1997). PUBMED 9100586 COMMENT Overlapping sequences: L06884, M21624, M94081, Z14996 FEATURES Location/Qualifiers source 1..301 /db_xref="H-InvDB:HIT000324541" /organism="Homo sapiens" /chromosome="14" /map="14q11.2" /isolate="patient HT139" /mol_type="mRNA" /clone_lib="TCR Valpha 6 homoduplex band" /clone="642" /cell_type="intrathyroidal CD8+ T cells" /tissue_type="thyroid" /rearranged /db_xref="taxon:9606" V_region 1..196 /product="T cell receptor alpha chain variable region" N_region 197..204 J_segment 205..301 /product="J49" BASE COUNT 86 a 73 c 68 g 74 t ORIGIN 1 aagttatggt ctattctggt acaagcagcc cagcagtggg gaaatgattt ttcttattta 61 tcaggggtct tatgaccagc aaaatgcaac agaaggtcgc tactcattga atttccagaa 121 ggcaagaaaa tccgccaacc ttgtcatctc cgcttcacaa ctgggggact cagcaatgta 181 cttctgtgca atgagaaagc cctcgaacac cggtaaccag ttctattttg ggacagggac 241 aagtttgacg gtcattccaa atatccagaa ccctgaccct gccgtgtacc agctgagaga 301 c //