LOCUS       X92063                   301 bp    mRNA    linear   HUM 17-JUL-1997
DEFINITION  H.sapiens mRNA for T cell receptor alpha chain (clone 642).
ACCESSION   X92063
VERSION     X92063.1
KEYWORDS    joining region; T cell receptor; T cell receptor alpha chain;
            variable region.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   McIntosh R.S.
  JOURNAL   Submitted (21-SEP-1995) to the INSDC. R.S. McIntosh, Univ. of
            Sheffield, Dept. of Medicine, Univ.Sheffield Clinical Sciences
            Centre, Northern General Hospital,Sheffield S5 7AU, UK
REFERENCE   2  (bases 1 to 301)
  AUTHORS   McIntosh R.S., Watson P.F., Weetman A.P.
  TITLE     Analysis of the T cell receptor V alpha repertoire in Hashimoto's
            thyroiditis: evidence for the restricted accumulation of CD8+ T
            cells in the absence of CD4+ T cell restriction
  JOURNAL   J. Clin. Endocrinol. Metab. 82(4), 1140-1146(1997).
   PUBMED   9100586
COMMENT     Overlapping sequences: L06884, M21624, M94081, Z14996
FEATURES             Location/Qualifiers
     source          1..301
                     /db_xref="H-InvDB:HIT000324541"
                     /organism="Homo sapiens"
                     /chromosome="14"
                     /map="14q11.2"
                     /isolate="patient HT139"
                     /mol_type="mRNA"
                     /clone_lib="TCR Valpha 6 homoduplex band"
                     /clone="642"
                     /cell_type="intrathyroidal CD8+ T cells"
                     /tissue_type="thyroid"
                     /rearranged
                     /db_xref="taxon:9606"
     V_region        1..196
                     /product="T cell receptor alpha chain variable region"
     N_region        197..204
     J_segment       205..301
                     /product="J49"
BASE COUNT           86 a           73 c           68 g           74 t
ORIGIN      
        1 aagttatggt ctattctggt acaagcagcc cagcagtggg gaaatgattt ttcttattta
       61 tcaggggtct tatgaccagc aaaatgcaac agaaggtcgc tactcattga atttccagaa
      121 ggcaagaaaa tccgccaacc ttgtcatctc cgcttcacaa ctgggggact cagcaatgta
      181 cttctgtgca atgagaaagc cctcgaacac cggtaaccag ttctattttg ggacagggac
      241 aagtttgacg gtcattccaa atatccagaa ccctgaccct gccgtgtacc agctgagaga
      301 c
//