LOCUS       X92013                   229 bp    mRNA    linear   HUM 17-JUL-1997
DEFINITION  H.sapiens mRNA for T cell receptor alpha chain (clone 316).
ACCESSION   X92013
VERSION     X92013.1
KEYWORDS    joining region; T cell receptor; T cell receptor alpha chain;
            variable region.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   McIntosh R.S.
  JOURNAL   Submitted (21-SEP-1995) to the INSDC. R.S. McIntosh, Univ. of
            Sheffield, Dept. of Medicine, Univ.Sheffield Clinical Sciences
            Centre, Northern General Hospital,Sheffield S5 7AU, UK
REFERENCE   2  (bases 1 to 229)
  AUTHORS   McIntosh R.S., Watson P.F., Weetman A.P.
  TITLE     Analysis of the T cell receptor V alpha repertoire in Hashimoto's
            thyroiditis: evidence for the restricted accumulation of CD8+ T
            cells in the absence of CD4+ T cell restriction
  JOURNAL   J. Clin. Endocrinol. Metab. 82(4), 1140-1146(1997).
   PUBMED   9100586
COMMENT     Overlapping sequences: M13726, M94081
FEATURES             Location/Qualifiers
     source          1..229
                     /db_xref="H-InvDB:HIT000324491"
                     /organism="Homo sapiens"
                     /chromosome="14"
                     /map="14q11.2"
                     /isolate="patient HT139"
                     /mol_type="mRNA"
                     /clone_lib="TCR Valpha 3 homoduplex band"
                     /clone="316"
                     /cell_type="intrathyroidal CD8+ T cells"
                     /tissue_type="thyroid"
                     /rearranged
                     /db_xref="taxon:9606"
     V_region        1..135
                     /product="T cell receptor alpha chain variable region"
     N_region        136..140
     J_segment       141..229
                     /product="J15"
BASE COUNT           65 a           57 c           53 g           54 t
ORIGIN      
        1 tttaatacgt tcaaatgaaa gagagaaaca cagtggaaga ttaagagtca cgcttgacac
       61 ttccaagaaa agcagttcct tgttgatcac ggcttcccgg gcagcagaca ctgcttctta
      121 cttctgtgct acggacgcga gaactgctct gatctttggg aagggaacca ccttatcagt
      181 gagttccaat atccagaacc ctgaccctgc cgtgtaccag ctgagagac
//