LOCUS X91148 3880 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for microsomal triglyceride transfer protein.
ACCESSION X91148
VERSION X91148.1
KEYWORDS microsomal triglyceride transfer protein; MTP gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3880)
AUTHORS Chester S.
JOURNAL Submitted (21-SEP-1995) to the INSDC. S.Chester, MRC Molecular
Medicine Group, Collier Building, R.P.M.S., Du Cane Road, London
W12 0NN, UK
REFERENCE 2 (bases 1 to 3880)
AUTHORS Narcisi T.M.E., Shoulders C.C., Chester S.A., Read J., Brett D.J.,
Harrison G.B., Grantham T.T., Fox M.F., Povey S., de Bruin T.W.A.,
Erkelens D.W., Muller D.P.R., Lloyd J.K., Scott J.
TITLE Mutations of the microsomal triglyceride-transfer-protein gene in
abetalipoproteinemia
JOURNAL Am. J. Hum. Genet. 57(6), 1298-1310(1995).
PUBMED 8533758
COMMENT Related entry X75500
FEATURES Location/Qualifiers
source 1..3880
/db_xref="H-InvDB:HIT000324446"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 25..1578
/gene="MTP"
/product="microsomal triglyceride transfer protein"
/db_xref="H-InvDB:HIT000324446.14"
/protein_id="CAA62585.1"
/translation="MILLAVLFLCFISSYSASVKGHTTGLSLNNDRLYKLTYSTEVLL
DRGKGKLQDSVGYRISSNVDVALLWRNPDGDDDQLIQITMKDVNVENVNQQRGEKSIF
KGKSPSKIMGKENLEALQRPTLLHLIHGKVKEFYSYQNEAVAIENIKRGLASLFQTQL
SSGTTNEVDISGNCKVTYQAHQDKVIKIKALDSCKIARSGFTTPNQVLGVSSKATSVT
TYKIEDSFVIAVLAEETHNFGLNFLQTIKGKIVSKQKLELKTTEAGPRLMSGKQAAAI
IKAVDSKYTAIPIVGQVFQSHCKGCPSLSELWRSTRKYLQPDNLSKAEAVRNFLAFIQ
HLRTAKKEEILQILKMENKEVLPQLVDAVTSAQTSDSLEAILDFLDFKSDSSIILQER
FLYACGFASHPNEELLRALISKFKGSIGSSDIRETVMIITGTLVRKLCQNEGCKLKAV
VEAKKLILGGLEKAEKKEDTRMYLLALKNALLPEGIPSLLKYAEAGEGPISHLATTAL
QRYDAPFHN"
regulatory <3860..>3880
/note="Location changed from '(3859.3860)..>3880' to
'<3860..>3880'"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1222 a 786 c 826 g 1046 t
ORIGIN
1 tgcagttgag gattgctggt caatatgatt cttcttgctg tgctttttct ctgcttcatt
61 tcctcatatt cagcttctgt taaaggtcac acaactggtc tctcattaaa taatgaccgg
121 ctgtacaagc tcacgtactc cactgaagtt cttcttgatc ggggcaaagg aaaactgcaa
181 gacagcgtgg gctaccgcat ttcctccaac gtggatgtgg ccttactatg gaggaatcct
241 gatggtgatg atgaccagtt gatccaaata acgatgaagg atgtaaatgt tgaaaatgtg
301 aatcagcaga gaggagagaa gagcatcttc aaaggaaaaa gcccatctaa aataatggga
361 aaggaaaact tggaagctct gcaaagacct acgctccttc atctaatcca tggaaaggtc
421 aaagagttct actcatatca aaatgaggca gtggccatag aaaatatcaa gagaggtctg
481 gctagcctat ttcagacaca gttaagctct ggaaccacca atgaggtaga tatctctgga
541 aattgtaaag tgacctacca ggctcatcaa gacaaagtga tcaaaattaa ggccttggat
601 tcatgcaaaa tagcgaggtc tggatttacg accccaaatc aggtcttggg tgtcagttca
661 aaagctacat ctgtcaccac ctataagata gaagacagct ttgttatagc tgtgcttgct
721 gaagaaacac acaattttgg actgaatttc ctacaaacca ttaaggggaa aatagtatcg
781 aagcagaaat tagagctgaa gacaaccgaa gcaggcccaa gattgatgtc tggaaagcag
841 gctgcagcca taatcaaagc agttgattca aagtacacgg ccattcccat tgtggggcag
901 gtcttccaga gccactgtaa aggatgtcct tctctctcgg agctctggcg gtccaccagg
961 aaatacctgc agcctgacaa cctttccaag gctgaggctg tcagaaactt cctggccttc
1021 attcagcacc tcaggactgc gaagaaagaa gagatccttc aaatactaaa gatggaaaat
1081 aaggaagtat tacctcagct ggtggatgct gtcacctctg ctcagacctc agactcatta
1141 gaagccattt tggacttttt ggatttcaaa agtgacagca gcattatcct ccaggagagg
1201 tttctctatg cctgtggatt tgcttctcat cccaatgaag aactcctgag agccctcatt
1261 agtaagttca aaggttctat tggtagcagt gacatcagag aaactgttat gatcatcact
1321 gggacacttg tcagaaagtt gtgtcagaat gaaggctgca aactcaaagc agtagtggaa
1381 gctaagaagt taatcctggg aggacttgaa aaagcagaga aaaaagagga caccaggatg
1441 tatctgctgg ctttgaagaa tgccctgctt ccagaaggca tcccaagtct tctgaagtat
1501 gcagaagcag gagaagggcc catcagccac ctggctacca ctgctctcca gagatatgat
1561 gctccctttc ataactgatg aggtgaagaa gaccttaaac agaatatacc accaaaaccg
1621 taaagttcat gaaaagactg tgcgcactgc tgcagctgct atcattttaa ataacaatcc
1681 atcctacatg gacgtcaaga acatcctgct gtctattggg gagcttcccc aagaaatgaa
1741 taaatacatg ctcgccattg ttcaagacat cctacgtttt gaaatgcctg caagcaaaat
1801 tgtccgtcga gttctgaagg aaatggtcgc tcacaattat gaccgtttct ccaggagtgg
1861 atcttcttct gcctacactg gctacataga acgtagtccc cgttcggcat ctacttacag
1921 cctagacatt ctctactcgg gttctggcat tctaaggaga agtaacctga acatctttca
1981 gtacattggg aaggctggtc ttcacggtag ccaggtggtt attgaagccc aaggactgga
2041 agccttaatc gcagccaccc ctgacgaggg ggaggagaac cttgactcct atgctggtat
2101 gtcagccatc ctctttgatg ttcagctcag acctgtcacc tttttcaacg gatacagtga
2161 tttgatgtcc aaaatgctgt cagcatctgg cgaccctatc agtgtggtga aaggacttat
2221 tctgctaata gatcattctc aggaacttca gttacaatct ggactaaaag ccaatataga
2281 ggtccagggt ggtctagcta ttgatatttc aggtgcaatg gagtttagct tgtggtatcg
2341 tgagtctaaa acccgagtga aaaatagggt gactgtggta ataaccactg acatcacagt
2401 ggactcctct tttgtgaaag ctggcctgga aaccagtaca gaaacagaag caggcttgga
2461 gtttatctcc acagtgcagt tttctcagta cccattctta gtttgcatgc agatggacaa
2521 ggatgaagct ccattcaggc aatttgagaa aaagtacgaa aggctgtcca caggcagagg
2581 ttatgtctct cagaaaagaa aagaaagcgt attagcagga tgtgaattcc cgctccatca
2641 agagaactca gagatgtgca aagtggtgtt tgcccctcag ccggatagta cttccagcgg
2701 atggttttga aactgacctg tgatatttta cttgaatttg tctccccgaa agggacacaa
2761 tgtggcatga ctaagtactt gctctctgag agcacagcgt ttacatattt acctgtattt
2821 aagatttttg taaaaagcta caaaaaactg cagtttgatc aaatttgggt atatgcagta
2881 tgctacccac agcgtcattt tgaatcatca tgtgacgctt tcaacaacgt tcttagttta
2941 cttatacctc tctcaaatct catttggtac agtcagaata gttattctct aagaggaaac
3001 tagtgtttgt taaaaacaaa aataaaaaca aaaccacaca aggagaaccc aattttgttt
3061 caacaatttt tgatcaatgt atatgaagct cttgatagga cttccttaag catgacggga
3121 aaaccaaaca cgttccctaa tcaggaaaaa aaaaaaaaaa gaaaaagtaa gacacaaaca
3181 aaccattttt ttctcttttt ttggagttgg gggcccaggg agaagggaca aggcttttaa
3241 aagacttgtt agccaacttc aagaattaat atttatgtct ctgttattgt tagttttaag
3301 ccttaaggta gaaggcacat agaaataaca tctcatcttt ctgctgacca ttttagtgag
3361 gttgttccaa agagcattca ggtctctacc tccagccctg caaaaatatt ggacctagca
3421 cagaggaatc aggaaaatta atttcagaaa ctccatttga tttttctttt gctgtgtctt
3481 ttttgagact gtaatatggt acactgtcct ctaaggacat cctcatttta tctcaccttt
3541 ttgggggtga gagctctagt tcatttaact gtactctgca caatagctag gatgactaag
3601 agaacattgc ttcaagaaac tggtggattt ggatttccaa aatatgaaat aaggagaaaa
3661 atgtttttat ttgtatgaat taaaagatcc atgttgaaca tttgcaaata tttattaata
3721 aacagatgtg gtgataaacc caaaacaaat gacaggtgct tattttccac taaacacaga
3781 cacatgaaat gaaagtttag ctagcccact atttgttgta aattgaaaac gaagtgtgat
3841 aaaataaata tgtagaaatc aaaaaaaaaa aaaaaaaaaa
//