LOCUS X90846 3454 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for mixed lineage kinase 2.
ACCESSION X90846
VERSION X90846.1
KEYWORDS kinase 2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Dorow D.S., Devereux L., Tu G.F., Price G., Nicholl J.K.,
Sutherland G.R., Simpson R.J.
TITLE Complete nucleotide sequence, expression, and chromosomal
localisation of human mixed-lineage kinase 2
JOURNAL Eur. J. Biochem. 234(2), 492-500(1995).
PUBMED 8536694
REFERENCE 2 (bases 1 to 3454)
AUTHORS Dorow D.S.
JOURNAL Submitted (16-AUG-1995) to the INSDC. D.S. Dorow, Peter MacCallum
Cancer Institute, Research Division, Locked Bag #1 ABeckett Street,
Melbourne, Victoria 3000, AUSTRALIA
FEATURES Location/Qualifiers
source 1..3454
/db_xref="H-InvDB:HIT000324421"
/organism="Homo sapiens"
/map="19q13.2"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="lambda gt10"
/tissue_type="brain"
/db_xref="taxon:9606"
CDS 289..3153
/product="mixed lineage kinase 2"
/db_xref="GOA:Q02779"
/db_xref="H-InvDB:HIT000324421.14"
/db_xref="HGNC:HGNC:6849"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR001245"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR015785"
/db_xref="InterPro:IPR016231"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR035779"
/db_xref="InterPro:IPR036028"
/db_xref="PDB:2RF0"
/db_xref="UniProtKB/Swiss-Prot:Q02779"
/protein_id="CAA62351.1"
/translation="MEEEEGAVAKEWGTTPAGPVWTAVFDYEAAGDEELTLRRGDRVQ
VLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEE
IIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIAL
RGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPI
IHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIR
LSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFAR
LLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLR
TKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKP
RVRKRKGNFKRSRLLKLREGGSHISLPSGFEHKITVQASPTLDKRKGSDGASPPASPS
IIPRLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQ
KERVGGEERLKGLGEGSKQWSSSAPNLGKSPKHTPIAPGFASLNEMEEFAEAEDGGSS
VPPSPYSTPSYLSVPLPAEPSPGARAPWEPTPSAPPARWGHGARRRCDLALLGCATLL
GAVGLGADVAEARAADGEEQRRWLDGLFFPRAGRFPRGLSPPARPHGRREDVGPGLGL
APSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPPAPTPTPSPSTNPLVDLE
LESFKKDPGQSLTPTHVTAVCAVSRGHRRTPSDGALGQRGPPEPAGHGPGPRDLLDFP
RLPDPQALFPARRRPPEFPGRPTTLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPS
RPDTPESPGPPSVQPTLLDMDMEGQNQDSTVPLCGAHGSH"
BASE COUNT 594 a 1217 c 1136 g 507 t
ORIGIN
1 cgcgcggcca ggccctctta gccctctgcc gtttgggggg cacgggtgaa cctgccgccc
61 cactcccacc ccgccccgcc ccgcccgtac agacaaatcg gaagggacga gcctgccctt
121 tgaaagggtt ttttttcttg ctcctgcgga gggcgcccca gccatggccc tcaggagctc
181 cctagacccc gcagggactg ccctccatcc cggccgccgg ggcccgccct ctgcatcccg
241 cgggcagcct gtgtgaagcg gcctcccgca gcccccggcc cctcccccat ggaggaggag
301 gagggggcgg tggccaagga gtggggcacg acccccgcgg ggcccgtctg gaccgcggtg
361 ttcgactacg aggcggcggg cgacgaggag ctgaccctgc ggaggggcga tcgcgtccag
421 gtgctttccc aagactgtgc ggtgtccggc gacgagggct ggtggaccgg gcagctcccc
481 agcggccgcg tgggcgtctt ccccagcaac tacgtggccc ccggcgcccc cgctgcaccc
541 gcgggcctcc agctgcccca ggagatcccc ttccacgagc tgcagctaga ggagatcatc
601 ggtgtggggg gctttggcaa ggtctatcgg gccctgtggc gtggcgagga ggtggcagtc
661 aaggccgccc ggctggaccc tgagaaggac ccggcagtga cagcggagca ggtgtgccag
721 gaagcccggc tctttggagc cctgcagcac cccaacataa ttgcccttag gggcgcctgc
781 ctcaaccccc cacacctctg cctagtgatg gagtatgccc ggggtggtgc actgagcagg
841 gtgctggcag gtcgccgggt gccacctcac gtgctggtca actgggctgt gcaggtggcc
901 cggggcatga actacctaca caatgatgcc cctgtgccca tcatccaccg ggacctcaag
961 tccatcaaca tcctgatcct ggaggccatc gagaaccaca acctcgcaga cacggtgctc
1021 aagatcacgg acttcggcct cgcccgcgag tggcacaaga ccaccaagat gagcgctgcg
1081 gggacctacg cctggatggc gccggaggtt atccgtctct ccctcttctc caaaagcagt
1141 gatgtctgga gcttcggggt gctgctgtgg gagctgctga cgggggaggt cccctaccgt
1201 gagatcgacg ccttggccgt ggcgtatggc gtggctatga ataagctgac gctgcccatt
1261 ccctccacgt gccccgagcc ctttgcccgc ctcctggagg aatgctggga cccagacccc
1321 cacgggcggc cagatttcgg tagcatcttg aagcggcttg aagtcatcga acagtcagcc
1381 ctgttccaga tgccactgga gtccttccac tcgctgcagg aagactggaa gctggagatt
1441 cagcacatgt ttgatgacct tcggaccaag gagaaggagc ttcggagccg tgaggaggag
1501 ctgctgcggg cggcacagga gcagcgcttc caggaggagc agctgcggcg gcgggagcag
1561 gagctggcag aacgtgagat ggacatcgtg gaacgggagc tgcacctgct catgtgccag
1621 ctgagccagg agaagccccg ggtccgcaag cgcaagggca acttcaagcg cagccgcctg
1681 ctcaagctgc gggaaggcgg cagccacatc agcctgccct ctggctttga gcataagatc
1741 acagtccagg cctctccaac tctggataag cggaaaggat ccgatggggc cagcccccct
1801 gcaagcccca gcatcatccc ccggctgagg gccattcgcc tgactcccgt ggactgtggt
1861 ggcagcagca gtggcagcag cagtggagga agtgggacat ggagccgcgg tgggccccca
1921 aagaaggaag aactggtcgg gggcaagaag aagggacgaa cgtgggggcc cagctccacc
1981 ctgcagaagg agcgggtggg aggagaggag aggctgaagg ggctggggga aggaagcaaa
2041 cagtggtcat caagtgcccc caacctgggc aagtccccca aacacacacc catcgcccct
2101 ggcttcgcca gcctcaatga gatggaggag ttcgcggagg cagaggatgg aggcagcagc
2161 gtgccccctt ccccctactc gaccccgtcc tacctctcag tgccactgcc tgccgagccc
2221 tccccggggg cgcgggcgcc gtgggagccg acgccgtccg cgccccccgc tcggtgggga
2281 cacggcgccc ggcggcgctg cgacctggcg ctgctaggct gcgccacgct gctgggggct
2341 gtgggcctgg gcgccgacgt ggccgaggcg cgcgcggccg acggtgagga gcagcggcgc
2401 tggctcgacg gcctcttctt tccccgcgcc ggccgcttcc cgcggggcct cagcccaccc
2461 gcgcgtcccc acggccgccg cgaagacgtg ggccccggcc tgggcctggc gccctcggcc
2521 accctcgtgt cgctgtcgtc cgtgtccgac tgcaactcca cgcgttcact gctgcgctct
2581 gacagtgacg aggccgcacc ggccgcgccc tccccaccac cctccccgcc cgcgcccaca
2641 cccacgccct cgcccagcac caaccccctg gtggacctgg agctggagag cttcaagaag
2701 gaccccggcc agtcgctcac gcccacccac gtcacggctg tatgcgctgt gagccgcggg
2761 caccggcgga cgccatcgga tggggcgctg gggcagcggg ggccgcccga gcccgcgggc
2821 catggccctg gccctcgtga ccttctggac ttcccccgcc tgcccgaccc ccaggctctg
2881 ttcccagccc gccgccggcc ccctgagttc ccaggccgcc ccaccaccct gacctttgcc
2941 ccgagacctc ggccggctgc cagtcgcccc cgcttggacc cctggaaact ggtctccttc
3001 ggccggacac tcaccatctc gcctcccagc aggccagaca ctccggagag ccctgggccc
3061 cccagcgtgc agcccacact gctggacatg gacatggagg ggcagaacca agacagcaca
3121 gtgcccctgt gcggggccca cggctcccac taaggcctgc ccaccaccgc ccgcctgggc
3181 agccatgaat gtagcgcccc aggccctgcc ccagcccgcc atgccacaag gtgggggagg
3241 ccctgggcag gatgttcact ctatttattg gggaaggagg gagggggggg acacttaact
3301 tattcctttg taccccaggg ggtggagccc tgtgcccacc ctgcactggg gggagggtgg
3361 gcagggatac tcagggacag ggcatcatgg gggatttggc acaaaatgga acaataaagg
3421 taaccccttg cccccccccc caaaaaaaaa aaaa
//