LOCUS X89984 4522 bp mRNA linear HUM 14-NOV-2006
DEFINITION H.sapiens mRNA for BCL7A protein.
ACCESSION X89984
VERSION X89984.1
KEYWORDS alternative splicing; bcl7a gene; CGG-repeat; TG repeat.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Zani V.J., Dyer M.J.S., Asou N., Jadayel D., Heward J.M.,
Shipley J., Nacheva E., Takasuki K., Catovsky D., Dyer M.J.
TITLE Molecular cloning of complex chromosomal translocation
t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line
defines a new gene (BCL7A) with homology to caldesmon
JOURNAL Blood 87(8), 3124-3134(1996).
PUBMED 8605326
REFERENCE 2 (bases 1 to 4522)
AUTHORS Dyer M.J.S.
JOURNAL Submitted (25-JUL-1995) to the INSDC. M.J.S. Dyer, Institute of
Cancer Research, Academic Haematology, 15 Cotswold Road, Sutton,
Surrey. SM2 5NG, UK
FEATURES Location/Qualifiers
source 1..4522
/db_xref="H-InvDB:HIT000324399"
/organism="Homo sapiens"
/chromosome="12"
/map="12q24.13"
/mol_type="mRNA"
/dev_stage="fetus"
/clone_lib="Stratagene fetal brain"
/tissue_type="brain"
/db_xref="taxon:9606"
repeat_region 691..710
/rpt_unit_seq="CGG"
repeat_region 778..819
/rpt_unit_seq="TG"
CDS 954..1649
/gene="BCL7A"
/db_xref="GOA:Q4VC05"
/db_xref="H-InvDB:HIT000324399.14"
/db_xref="HGNC:HGNC:1004"
/db_xref="InterPro:IPR006804"
/db_xref="UniProtKB/Swiss-Prot:Q4VC05"
/protein_id="CAA62011.1"
/translation="MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLR
IYKWVPVTEPKVDDKNKNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADA
SPIKQENSSNSSPAPEPNSAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEH
SMNSSEKVDRQPSGDSGLAAETSAISQVPRSRSQRGSQIGREPIGLSGDLEGVPPSKK
MKLEASQQNSEEM"
exon 1515..1578
/note="alternatively spliced exon"
regulatory 3366..3370
/note="putative"
/regulatory_class="polyA_signal_sequence"
regulatory 4503..4508
/note="putative"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 980 a 1285 c 1245 g 1009 t
ORIGIN
1 cgggtctcag tctggtactg aatgcaggaa tggcttaagg tgaaatcgtg gtcctctggt
61 gaactcagcg aagaccccct cgccttgttt atgacaagag aacttctggg ggcgggagga
121 agagtccctg ttacgatgct gatcatcatt gagcttttgc tgagaaaact ctttagtact
181 aaggtcgaga gtctctgtgg tctgcctggc accagcacct tcctacaacc ctagttttcc
241 aaaaggaaaa gcctggggcc aggcgacgtc ctagctcgca ttatgacagg gccgcgggcc
301 accagagatg cgcgatgccc aactctttcc aagagcacct cgcgtcccga accggtgcct
361 tcaactcgga gaagtcaaga gacccgcaag aaacttgcac gactgcaccc gccgccgcgc
421 tgctgggggc tgggcagggg cagctgggct ggctcccggg gagacgcgac ccccccgcgc
481 cccgcagacc ggctgtctcc catggacccc tcggcacctg cagctccgag gaagggtcag
541 cgcgcgtgtc cgcaccccgc ccccaccgcg cgcccagagc cgggggtcgc cgtggccctt
601 cgccacctcc ccaggagggc gtccggggcg tcccctctgg gcgacgcgag gcccgggggn
661 ctgcggtggc cgcggcgcgg agccnnactc cggcggcggc ggcggcgcgg ctccccctgc
721 tctgtgcagc tgccgcccgg gcttgcgctg ggccaggcgc gcggcggccc cgggctttgt
781 gtgtgtgtat gtgtgtgtgt gtgtgtgtgt gtgtgtgtga gagtgtgtgc gtgtgagagt
841 gcgagtgtct gtgcgcgagt gagtgagcgg cgggcgggcg cgagtgtggc cggccggagc
901 gcgagcatga cccggcgggc gcgctcccca gcctccgtct ccccgccgga accatgtcgg
961 gcaggtcggt tcgagccgag acgaggagcc gggccaaaga tgatatcaag agggtcatgg
1021 cggcgatcga gaaagtgcgc aaatgggaga agaaatgggt gaccgttggt gacacatccc
1081 tacgaatcta caaatgggtc cctgtgacgg agcccaaggt tgatgacaaa aacaagaata
1141 agaaaaaagg caaggacgag aagtgtggct cagaggtgac cactccggag aacagttcct
1201 ccccagggat gatggacatg catgacgata acagcaacca gagctccatc gcagatgcct
1261 cccccatcaa acaggagaac agcagcaact ccagccccgc tccagagccc aactcggctg
1321 tgcccagcga cggcaccgag gccaaggtgg atgaggccca ggctgatggg aaggagcacc
1381 caggagctga agatgcttct gatgagcaga attcacagtc ctctatggaa cattcgatga
1441 acagctcaga gaaagtagat cggcagccgt ctggagactc gggtctggcc gcagagacgt
1501 ctgcaatctc tcaggtacct cgctcgaggt ctcagagggg cagccagatc ggccgggagc
1561 ccattgggtt gtcgggggat ctggaaggag tgccaccctc taaaaagatg aaactggagg
1621 cctctcaaca aaactccgaa gagatgtaga cgatgcttta agcctccgat aactgttcca
1681 tggaaggtac atcagcaatt aattctagag caactttgcc ccagcgattc ctcttgggtg
1741 cgaacagaac tactaacgtt tcaagtttac caagtgcaaa tccaagaaga cccagacggc
1801 gtcacttctc agacactgaa gaactctgct gtgaagcaaa acactcaaac ctttaaggga
1861 ctgtccttgg ggaggcaggc ggggctgaca gctcaggagt gtctgcacac tgtctcggaa
1921 gccaggattc catttgtgtt gctgctgtat ttccccccac ttctctatgt aacgatataa
1981 gctatcggag ggtggtaccg atcaggaacg ctttttggcg gggctttcca ctgttcaacc
2041 gattccttcc gctttctttt tttgtgcctt gtgcccttga ggtgacctct ggcatgtatc
2101 ctggtggttc ttacatcccc ctctgcaaag tgccctcttg gtttggttcg ggcggcggct
2161 gccaccctac tcaccgctct cctccctgcc ccaggacttc atcggagcag gcagggtgga
2221 gcgaaggagc tccttagccc acctggtttg caggtgcagg gggaccttag gcacgcccca
2281 agcaccaggc accagggccc aaggacgcgc aggtgttggg gcacagtccc caagggctcg
2341 gccccttgga tcaggctggg cactcgctgt gctctcccct ccttggggcg tttaggactg
2401 ggcgtctcca agcccaccat ggcccagatg gacgtgcaaa gcccttggaa ttttctggca
2461 cttcctctct attgccccca ccaccaccac ccccatcact gctttctccc agacctccga
2521 atacgaaatg gcttctctgg ctgactgcaa ggctgtctcc ttaaggcact gagtgggccg
2581 gggaggctgg gagccggcgg caggattagc tggtgctgaa ctttctctca taggacgtcg
2641 cttggatttc aaatccacgg tcacctgctg ccctttgcct cccccgacgc cccagcctgt
2701 gccccggaga ggcaggatcg cagtggtcag aatccacgtg ctttcctatt ctcaggctgt
2761 tctgactctg agccaacagc tggaccgtgt ctcatcccca gaacatgccg tctgtccacc
2821 ggggagtggc cttgatggcc ggcctcgaag gccacaaaca aggcgtcgag gaattggaaa
2881 gatttgcaca ccctccagaa aggagagacg caatctcccc tccctcccat cccccacctt
2941 cgctggaaca gcttcctctc actgaacgga gacgccccct tggacgaact gcctaatcgt
3001 ttggttctga ggcctggttt gctcttaatt aatatatgaa ctcctcagac cttaaacctt
3061 ttcctaagct ttctttactg cactggagtt ctgactccct ttgagttgtg tgttactggg
3121 ggtggggtgg ggtcatgggt tttgttgttt ttgggggcta attggtgcat attcaggtac
3181 cacctttgac gtgtggctct ttctcctgac catcatggga agtgtctgct ggattccatt
3241 ttctaagagt ttctgagggt gaggctctta tttttttttt aagggatcct gtctatttcc
3301 tgcacttcga gaagaatcaa aatgttcctg aatttcaaat acctcatgca aaatgtgtct
3361 cctgaaataa gggaaaaaaa aaaaaaacca caactttgaa aatcttaatg ttgaagttag
3421 caatgccgaa aggtttctgt cttaaaaaaa aaaaatcctt gtacttatca attttgcccc
3481 ttaggcagtc agttttgttg agaactgtgt cctgcatcct ggcgcagaac ctcctgatgc
3541 ggttcctctc cacgcatctc gaggcggcgt tacctccaga ttccgtagag ttagagtcac
3601 atttttcttt gcagcgaaac tccgtcttgg tgagagatga atttggatat ttatttcctt
3661 ctctgttttt gggaaacgag aggctacaac caagacagct gaaggagaat gaaacacaca
3721 tccacagaaa cagagaggcg taggtggccc tgccgttgac cgcagcctct ctggacaggc
3781 aaggggagtt ggcgcaggtg aggactcaga cgacgtccac cgtcccaagg ctgtcactag
3841 tatttctctg aagtgcctga aggtaggaat gggccggcga ttgggaccag ctgggcccca
3901 ccacggccac gccaggcaaa gcgccagcag ccctgcactc cacgctggcc aagaaggcct
3961 tccacgcaga atgacaagac tgcaaaaatc cgatgtgctt ccttccctgg cgcagtcgct
4021 cctcgagccg ctgcccccca cccaccctgc acccctcgcc ctccccccca ccacagaatc
4081 taagaccttt cagcttcgag ccagggggcg ggggatcccg agcaaaagcc ttccatggac
4141 atcaggcccc gtggcctcaa gggctcccag ggcaaaccta attcccccaa aacgtgaagt
4201 cggggaagct gcggctacac attccacaaa gtgctggcac ttacacccac aacccggaag
4261 gctgtggacc gattcctcta gggtggtgac ctcccattag caaacggtgt catggtttgg
4321 aatgttcatt atcgccaaga acctggttag aggcataaag accttttttc accgttacct
4381 aattttttcc cctttcaaga attttttttt tttttggtgt gttgtacagc agtataattt
4441 ttcacttatt tattcctaca gtagatatgg tttgtacaat gtacaattgt ttcatttcag
4501 aaaataaaaa tttcaaatca tg
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