LOCUS X89066 4085 bp mRNA linear HUM 07-OCT-1996
DEFINITION H.sapiens mRNA for TRPC1 protein.
ACCESSION X89066
VERSION X89066.1
KEYWORDS transient receptor potential channel; TRPC1 gene; TRPC1 protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Wes P.D., Chevesich J., Jeromin A., Rosenberg C., Stetten G.,
Montell C.
TITLE TRPC1, a human homolog of a Drosophila store-operated channel
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92(21), 9652-9656(1995).
PUBMED 7568191
REFERENCE 2
AUTHORS Montell C.
JOURNAL Submitted (06-JUL-1995) to the INSDC. C. Montell, The Johns Hopkins
Univ. School of Med., Dept of Biological Chemistry, 725 N. Wolfe
Street, Baltimore MD 21218, USA
REMARK Revised by [3]
REFERENCE 3
AUTHORS Montell C.
JOURNAL Submitted (02-AUG-1995) to the INSDC. C. Montell, The Johns Hopkins
Univ. School of Med., Dept of Biological Chemistry, 725 N. Wolfe
Street, Baltimore MD 21205-2185, USA
REMARK Revised by [4]
REFERENCE 4
AUTHORS Montell C.
JOURNAL Submitted (27-SEP-1995) to the INSDC. C. Montell, The Johns Hopkins
Univ. School of Med., Dept of Biological Chemistry, 725 N. Wolfe
Street, Baltimore MD 21205-2185, USA
REMARK Revised by [5]
REFERENCE 5 (bases 1 to 4085)
AUTHORS Montell C.
JOURNAL Submitted (06-JUN-1996) to the INSDC. C. Montell, The Johns Hopkins
Univ. School of Med., Dept of Biological Chemistry, 725 N. Wolfe
Street, Baltimore MD 21205-2185, USA
COMMENT Related sequences T07204, Z41868, Z38167, R41698, R18151, R52601,
R52545
FEATURES Location/Qualifiers
source 1..4085
/db_xref="H-InvDB:HIT000324341"
/organism="Homo sapiens"
/chromosome="3"
/map="q22-q24"
/mol_type="mRNA"
/dev_stage="fetal"
/clone_lib="lZAP"
/clone="stratagene"
/tissue_type="brain"
/db_xref="taxon:9606"
CDS 138..2417
/gene="trpc1"
/product="TRPC1 protein"
/note="transient receptor potential channel related"
/db_xref="GOA:P48995"
/db_xref="H-InvDB:HIT000324341.13"
/db_xref="HGNC:HGNC:12333"
/db_xref="InterPro:IPR002110"
/db_xref="InterPro:IPR002153"
/db_xref="InterPro:IPR005457"
/db_xref="InterPro:IPR005821"
/db_xref="InterPro:IPR013555"
/db_xref="InterPro:IPR036770"
/db_xref="UniProtKB/Swiss-Prot:P48995"
/protein_id="CAA61447.1"
/translation="MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEEN
TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQL
LLDYGCQKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCE
CTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEV
EFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRL
KLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCY
LIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYL
LILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFA
DRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLG
MFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFS
LAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDK
EWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNS
LKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNE
IRDLLGFRTSKYAMFYPRN"
BASE COUNT 1196 a 687 c 801 g 1400 t
ORIGIN
1 ccgggcctcg agccgaggca gcagtgggaa cgactcatcc tttttccagc cctggggcgt
61 ggctggggtc ggggtcgggg tcggggccgg tgggggcccc gcccccgtct cctggcctgc
121 ccccttcatg ggccgcgatg atggcggccc tgtacccgag cacggacctc tcgggcgcct
181 cctcctcctc cctgccttcc tctccatcct cttcctcgcc gaacgaggtg atggcgctga
241 aggatgtgcg ggaggtgaag gaggagaata cgctgaatga gaagcttttc ttgctggcgt
301 gcgacaaggg tgactattat atggttaaaa agattttgga ggaaaacagt tcaggtgact
361 tgaacataaa ttgcgtagat gtgcttggga gaaatgctgt taccataact attgaaaacg
421 aaaacttgga tatactgcag cttcttttgg actacggttg tcagaaacta atggaacgaa
481 ttcagaatcc tgagtattca acaactatgg atgttgcacc tgtcatttta gctgctcatc
541 gtaacaacta tgaaattctt acaatgctct taaaacagga tgtatctcta cccaagcccc
601 atgcagttgg ctgtgaatgc acattgtgtt ctgcaaaaaa caaaaaggat agcctccggc
661 attccaggtt tcgtcttgat atatatcgat gtttggccag tccagctcta ataatgttaa
721 cagaggagga tccaattctg agagcatttg aacttagtgc tgatttaaaa gaactaagtc
781 ttgtggaggt ggaattcagg aatgattatg aggaactagc ccggcaatgt aaaatgtttg
841 ctaaggattt acttgcacaa gcccggaatt ctcgtgaatt ggaagttatt ctaaaccata
901 cgtctagtga cgagcctctt gacaaacggg gattattaga agaaagaatg aatttaagtc
961 gtctaaaact tgctatcaaa tataaccaga aagagtttgt ctcccagtct aactgccagc
1021 agttcctgaa cactgtttgg tttggacaga tgtcrggtta ccgacgcaag cccacctgta
1081 agaagataat gactgttttg acagtaggca tcttttggcc agttttgtca ctttgttatt
1141 tgatagctcc caaatctcag tttggcagaa tcattcacac accttttatg aaatttatca
1201 ttcatggagc atcatatttc acatttctgc tgttgcttaa tctatactct cttgtctaca
1261 atgaggataa gaaaaacaca atggggccag cccttgaaag aatagactat cttcttattc
1321 tgtggattat tgggatgatt tggtcagaca ttaaaagact ctggtatgaa gggttggaag
1381 actttttaga agaatctcgt aatcaactca gttttgtcat gaattctctt tatttggcaa
1441 cctttgccct caaagtggtt gctcacaaca agtttcatga ttttgctgat cggaaggatt
1501 gggatgcatt ccatcctaca ctggtggcag aagggctttt tgcatttgca aatgttctaa
1561 gttatcttcg tctctttttt atgtatacaa ccagctctat cttgggtcca ttacagattt
1621 caatgggaca gatgttacaa gattttggaa aatttcttgg gatgtttctt cttgttttgt
1681 tttctttcac aattggactg acacaactgt atgataaagg atatacttca aaggagcaga
1741 aggactgtgt aggcatcttc tgtgaacagc aaagcaatga taccttccat tcgttcattg
1801 gcacctgctt tgctttgttc tggtatattt tctccttagc gcatgtggca atctttgtca
1861 caagatttag ctatggagaa gaactgcagt cctttgtggg agctgtcatt gttggtacat
1921 acaatgtcgt ggttgtgatt gtgcttacca aactgctggt ggcaatgctt cataaaagct
1981 ttcagttgat agcaaatcat gaagacaaag aatggaagtt tgctcgagca aaattatggc
2041 ttagctactt tgatgacaaa tgtacgttac ctccaccttt caacatcatt ccctcaccaa
2101 agactatctg ctatatgatt agtagcctca gtaagtggat ttgctctcat acatcaaaag
2161 gcaaggtcaa acggcaaaac agtttaaagg aatggagaaa tttgaaacag aagagagatg
2221 aaaactatca aaaagtgatg tgctgcctag tgcatcgtta cttgacttcc atgagacaga
2281 agatgcaaag tacagatcag gcaactgtgg aaaatctaaa cgaactgcgc caagatctgt
2341 caaaattccg aaatgaaata agggatttac ttggctttcg gacttctaaa tatgctatgt
2401 tttatccaag aaattaacca ttttctaaat catggagcga ataattttca ataacagatc
2461 caaaagacta tattgcataa cttgcaatga aattaatgag atatatattg aaataaagaa
2521 ttatgtaaaa gccattcttt aaaatattta tagcataaat atatgttatg taaagtgtgt
2581 atatagaatt agttttttaa accttctgtt agtggctttt tgcagaagca aaacagatta
2641 agtagataga ttttgttagc atgctgcttg gttttcttac ttagtgcttt aaaatgtttt
2701 tttttatgtt taagaggggc agttataaat ggacacattg cccagaatgt tttgtaaaat
2761 gaagaccagc aaatgtaggc tgatctcctt cacaggatac acttgaaata tagaagttat
2821 gttttaaata tctctgtttt aggagttcac atatagttca gcatttattg tttaggagta
2881 taattttatt ttatctaaaa taatagtcta ttttttcttt tgtattttgt tataatctta
2941 agcaacaaag aaaaaaccct aatatttgaa tctatttatg tctttcaatt taaattcact
3001 tcagtttttg ttattgtaat atatttactt ttacatggtt ataatcactt tatattttta
3061 atgttttttt cacttaatat tttatatata catttccatg tattgatgta gttagtccac
3121 atttaaattt ttatagaatt atatagtttt tgaaaaatac agtcagtaga tgttttattt
3181 tttagctatt cagttatgtt tataagtttg catagctact tctcgacatt tggtttgttt
3241 taattttttt gtatcataat agtcctattt ttttttcaag ttggagtgaa tgtttttagt
3301 tttaagatag ataggagaca cttttttatc acatgtagtc acaacctgtt ttgtttttgt
3361 aaaacatagg aagtctcttt aatgcaatga tttgttttat atttggacta aggttcttga
3421 gcttatctcc caaggtactt tccataattt aacacagctt ctataaaagt gacttcatgc
3481 ttacttgtgg atcattcttg ctgcttaaga tgaaaagcat tggtttttta aaattagaga
3541 ataaaatatg tatttaaatt tttggtgtgt tcacataaag ggatgtagct aaaatgtttt
3601 cataggctat tatatattct cgcagcattt ccagttaaga ggatattagg tatataattc
3661 tcttcttaac cgaatgtcag atggtcttac gccacagggt gcaggtaacc cttggtctgt
3721 aagcaccacc gatccaggga tcattgtcta aataggttac tattgtttgt ttcatcttgc
3781 ttttgcattt ttatttttta atttccaaat tttaagtgtt ccctctttgg ggcaaattct
3841 tataaaaatg tttattgtaa agttatatat tttgtctacg atgggattat gcacttccca
3901 attgggattt tacatctgga tttttagtca ttctaaaaaa cacctaatta ttaaaacatt
3961 tatagagtgc ctactgtatg catgagttga gttgcttctg aggtacattt tgaatgacag
4021 catattgtaa gaaaaaaaaa ggtgaataaa atttgacatt agattataaa aaaaaaaagg
4081 aattc
//