LOCUS X87904 6643 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for semaphorin receptor (plexin-B1/SEP gene).
ACCESSION X87904
VERSION X87904.2
KEYWORDS plasma membrane receptor; plexin-B1/SEP gene; semaphorin receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 2
AUTHORS Longati P.
JOURNAL Submitted (12-JUN-1995) to the INSDC. P. Longati, Molecular
Medicine Unit, Beth Israel Hospital, 330, Brookline Avenue, Boston
MA 02, USA
REMARK Revised by [5]
REFERENCE 3 (bases 1 to 4700)
AUTHORS Maestrini E., Tamagnone L., Longati P., Cremona O., Gulisano M.,
Bione S., Tamanini F., Neel B.G., Toniolo D., Comoglio P.M.
TITLE A family of transmembrane proteins with homology to the
MET-hepatocyte growth factor receptor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 93(2), 674-678(1996).
PUBMED 8570614
REFERENCE 4
AUTHORS Tamagnone L., Artigiani S., Chen H., He Z., Ming G.L., Song H.L.,
Chedotal A., Winberg M.L., Goodman C.S., Poo M.M.,
Tessier-Lavigne M., Comoglio P.M.
TITLE Plexins are a large family of receptors for transmembrane,
secreted, and GPI-anchored semaphorins in vertebrates
JOURNAL Cell 99(1), 71-80(1999).
PUBMED 10520995
REFERENCE 5 (bases 1 to 6643)
AUTHORS Tamagnone L.
JOURNAL Submitted (01-OCT-1999) to the INSDC. L. Tamagnone, University of
Torino, IRCC, SP 142, 10060 Candiolo, Torino, ITALY
FEATURES Location/Qualifiers
source 1..6643
/db_xref="H-InvDB:HIT000324332"
/organism="Homo sapiens"
/chromosome="3"
/mol_type="mRNA"
/dev_stage="foetus"
/tissue_type="brain"
/db_xref="taxon:9606"
CDS 1..6408
/gene="plexin-B1/SEP"
/product="semaphorin receptor"
/db_xref="GOA:O43157"
/db_xref="H-InvDB:HIT000324332.12"
/db_xref="HGNC:HGNC:9103"
/db_xref="InterPro:IPR001627"
/db_xref="InterPro:IPR002165"
/db_xref="InterPro:IPR002909"
/db_xref="InterPro:IPR008936"
/db_xref="InterPro:IPR013548"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR014756"
/db_xref="InterPro:IPR015943"
/db_xref="InterPro:IPR016201"
/db_xref="InterPro:IPR031148"
/db_xref="InterPro:IPR036352"
/db_xref="InterPro:IPR041019"
/db_xref="InterPro:IPR041362"
/db_xref="PDB:2JPH"
/db_xref="PDB:2OS6"
/db_xref="PDB:2R2O"
/db_xref="PDB:2REX"
/db_xref="PDB:3HM6"
/db_xref="PDB:3OL2"
/db_xref="PDB:3SU8"
/db_xref="PDB:3SUA"
/db_xref="PDB:5B4W"
/db_xref="UniProtKB/Swiss-Prot:O43157"
/protein_id="CAB57277.1"
/translation="MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTS
GTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLL
VSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGL
AGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHF
VSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLI
QAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN
RTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPL
EATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRC
SRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPGE
SYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSL
SFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSP
DPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWA
GSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVA
AVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWT
GGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGLWELEEATLGASSCP
CVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPP
PDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCS
RCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRV
TIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVP
GRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPC
HLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKS
FLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPNQGLGRRRRVVPETACSLGPSCSS
QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADP
TLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLY
CEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLG
VGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMT
DLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLL
NSKLFLTKFIHTLETQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV
AKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSV
TGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKM
LDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVP
DGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRR
GSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL
DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTF
MDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAEL
SWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKV
TDL"
BASE COUNT 1229 a 2093 c 2020 g 1301 t
ORIGIN
1 atgcctgctc tgggcccagc tcttctccag gctctctggg ccgggtgggt cctcaccctc
61 cagccccttc caccaactgc attcactccc aatggcacgt atctgcagca cctggcaagg
121 gaccccacct caggcaccct ctacctgggg gctaccaact tcctgttcca gctgagccct
181 gggctgcagc tggaggccac agtgtccacc ggccctgtgc tagacagcag ggactgcctg
241 ccacctgtga tgcctgatga gtgcccccag gcccagccta ccaacaaccc gaatcagctg
301 ctcctggtga gcccaggggc cctggtggta tgcgggagcg tgcaccaggg ggtctgtgaa
361 cagcggcgcc tggggcagct cgagcagctg ctgctgcggc cagagcggcc tggggacaca
421 caatatgtgg ctgccaatga tcctgcggtc agcacggtgg ggctggtagc ccagggcttg
481 gcaggggagc ccctcctgtt tgtggggcga ggatacacca gcaggggtgt ggggggtggc
541 attccaccca tcacaacccg ggccctgtgg ccgcccgacc cccaagctgc cttctcctat
601 gaggagacag ccaagctggc agtgggccgc ctctccgagt acagccacca cttcgtgagt
661 gcctttgcac gtggggccag cgcctacttc ctgttcctgc ggcgggacct gcaggctcag
721 tctagagctt ttcgtgccta tgtatctcga gtgtgtctcc gggaccagca ctactactcc
781 tatgtggagt tgcctctggc ctgcgaaggt ggccgctacg ggctgatcca ggctgcagct
841 gtggccacgt ccagggaggt ggcgcatggg gaggtgctct ttgcagcttt ctcctcggct
901 gcacccccca ctgtgggccg gcccccatcg gcggctgctg gggcatctgg agcctctgcc
961 ctctgtgcct tccccctgga tgaggtggac cggcttgcta atcgcacgcg agatgcctgc
1021 tacacccggg agggtcgtgc tgaggatggg accgaggtgg cctacatcga gtatgatgtc
1081 aattctgact gtgcacagct gccagtggac accctggatg cttatccctg tggctcagac
1141 cacacgccca gccccatggc cagccgggtc ccgctggaag ccacaccaat tctggagtgg
1201 ccagggattc agctaacagc tgtggcagtc accatggaag atggacacac catcgctttc
1261 ctgggtgata gtcaagggca gctgcacagg gtctacttgg gcccagggag cgatggccac
1321 ccatactcca cacagagcat ccagcagggg tctgcagtga gcagagacct cacctttgat
1381 gggacctttg agcacctgta tgtcatgacc cagagcacac ttctgaaggt tcctgtggct
1441 tcctgtgctc agcacctgga ctgtgcatct tgccttgctc acagggaccc atactgtggg
1501 tggtgcgtgc tccttggcag gtgcagtcgc cgttctgagt gctcgagggg ccagggccca
1561 gagcagtggc tatggagctt ccagcctgag ctgggctgtc tgcaagtggc agccatgagt
1621 cctgccaaca tcagccgaga ggagacgagg gaggttttcc tatcagtgcc agacctgcca
1681 cccctgtggc caggggagtc atattcctgc cactttgggg aacatcagag tcctgccctg
1741 ctgactggtt ctggtgtgat gtgcccctcc ccagacccta gtgaggcccc agtgctgccg
1801 agaggagccg actacgtatc cgtgagcgtg gagctcagat ttggcgctgt tgtgatcgcc
1861 aaaacttccc tctctttcta tgactgtgtg gcggtcactg aactccgccc atctgcgcag
1921 tgccaggcct gtgtgagcag ccgctggggg tgtaactggt gtgtctggca gcacctgtgc
1981 acccacaagg cctcgtgtga tgctgggccc atggttgcaa gccatcagag cccgcttgtc
2041 tccccagacc ctcctgcaag aggtggaccc agcccctccc cacccacagc ccccaaagcc
2101 ctggccaccc ctgctcctga cacccttccc gtggagcctg gggctccctc cacagccaca
2161 gcttcggaca tctcacctgg ggctagtcct tccctgctca gcccctgggg gccatgggca
2221 ggttctggct ccatatcttc ccctggctcc acagggtcgc ctctccatga ggagccctcc
2281 cctcccagcc cccaaaatgg acctggaacc gctgtccctg cccccactga cttcagaccc
2341 tcagccacac ctgaggacct cttggcctcc ccgctgtcac cctcagaggt agcagcagtg
2401 ccccctgcag accctggccc cgaggctctt catcccacag tgcccctgga cctgccccct
2461 gccactgttc ctgccaccac tttcccaggg gccatgggct ccgtgaagcc cgccctggac
2521 tggctcacga gagaaggcgg cgagctgccc gaggcggacg agtggacggg gggtgacgca
2581 cccgccttct ccacttccac cctcctctca ggtgatggag actcagcaga gcttgagggc
2641 cctcccgccc ccctcatcct cccgtccagc ctcgactacc agtatgacac ccccgggctc
2701 tgggagctgg aagaggcgac cttgggggca agctcctgcc cctgtgtgga gagcgttcag
2761 ggctccacgt tgatgccggt ccatgtggag cgggaaatcc ggctgctagg caggaacctg
2821 caccttttcc aggatggccc aggagacaat gagtgtgtga tggagctgga gggcctcgag
2881 gtggtggttg aggcccgggt cgagtgtgag ccacctccag atacccagtg ccatgtcacc
2941 tgccagcagc accagctcag ctatgaggct ctgcagccgg agctccgtgt ggggctgttt
3001 ctgcgtcggg ccggccgtct gcgtgtggac agtgctgagg ggctgcatgt ggtactgtat
3061 gactgttccg tgggacatgg agactgcagc cgctgccaaa ctgccatgcc ccagtatggc
3121 tgtgtgtggt gtgaggggga gcgtccacgt tgtgtgaccc gggaggcctg tggtgaggct
3181 gaggctgtgg ccacccagtg cccagcgccc ctcatccact cggtggagcc actgactggg
3241 cctgtagacg gaggcacccg tgtcaccatc aggggctcca acctgggcca gcatgtgcag
3301 gatgtgctgg gcatggtcac ggtggctgga gtgccctgtg ctgtggatgc ccaggagtac
3361 gaggtctcca gcagcctcgt gtgcatcacc ggggccagtg gggaggaggt ggccggcgcc
3421 acagcggtgg aggtgccggg aagaggacgt ggtgtctcag aacacgactt tgcctaccag
3481 gatccgaagg tccattccat cttcccggcc cgcggcccca gagctggggg cacccgtctc
3541 accctgaatg gctccaagct cctgactggg cggctggagg acatccgagt ggtggttgga
3601 gaccagcctt gtcacttgct gccggagcag cagtcagaac aactgcggtg tgagaccagc
3661 ccacgcccca cgcctgccac gctccctgtg gctgtgtggt ttggggccac ggagcggagg
3721 cttcaacgcg gacagttcaa gtataccttg gaccccaaca tcacctctgc tggccccacc
3781 aagagcttcc tcagtggagg acgtgagata tgcgtccgtg gccagaatct ggacgtggta
3841 cagacgccaa gaatccgggt gaccgtggtc tcgagaatgc tgcagcccaa ccaggggctt
3901 ggacggaggc gtcgcgtggt cccggagacg gcatgttccc ttggaccctc ctgcagtagc
3961 cagcaatttg aggagccgtg ccatgtcaac tcctcccagc tcatcacgtg ccgcacacct
4021 gccctcccag gcctgcctga ggacccctgg gtccgggtgg aatttatcct tgacaacctg
4081 gtctttgact ttgcaacact gaaccccaca cctttctcct atgaggccga ccccaccctg
4141 cagccactca accctgagga ccccaccatg ccattccggc acaagcctgg gagtgtgttc
4201 tccgtggagg gggagaacct ggaccttgca atgtccaagg aggaggtggt ggctatgata
4261 ggggatggcc cctgtgtggt gaagacgctg acgcggcacc acctgtactg cgagcccccc
4321 gtggagcagc ccctgccacg gcaccatgcc ctccgagagg cacctgactc tttgcctgag
4381 ttcacggtgc agatggggaa cttgcgcttc tccctgggtc acgtgcagta tgacggcgag
4441 agccctgggg cttttcctgt ggcagcccag gtgggcttgg gggtgggcac ctctcttctg
4501 gctctgggtg tcatcatcat tgtcctcatg tacaggagga agagcaagca ggccctgagg
4561 gactataaga aggttcagat ccagctggag aatctggaga gcagtgtgcg ggaccgctgc
4621 aagaaggaat tcacagacct catgactgag atgaccgatc tcaccagtga cctcctgggc
4681 agcggcatcc ccttcctcga ctacaaggtg tatgcggaga ggatcttctt ccctgggcac
4741 cgcgagtcgc ccttgcaccg ggacctgggt gtgcctgaga gcagacggcc cactgtagag
4801 caagggctgg ggcagctctc taacctgctc aacagcaagc tcttcctcac caagttcatc
4861 cacacgctgg agacccagcg caccttttca gctcgggacc gtgcctacgt ggcatctctg
4921 ctcaccgtgg cactgcatgg gaagcttgag tatttcactg acatcctccg cactctgctc
4981 agtgacctgg ttgcccagta tgtggccaag aaccccaagc tgatgctgcg caggacagag
5041 actgtggtgg agaagctgct caccaactgg atgtccatct gtctgtatac cttcgtgagg
5101 gactccgtag gggagcctct gtacatgctc tttcgaggga ttaagcacca agtggataag
5161 gggccagtgg acagtgtgac aggcaaggcc aaatacacct tgaacgacaa ccgcctgctc
5221 agagaggatg tggagtaccg tcccctgacc ttgaatgcac tattggctgt ggggcctggg
5281 gcaggagagg cccagggcgt gcccgtgaag gtcctagact gtgacaccat ctcccaggca
5341 aaggagaaga tgctggacca gctttataaa ggagtgcctc tcacccagcg gccagaccct
5401 cgcacccttg atgttgagtg gcggtctggg gtggccgggc acctcattct ttctgacgag
5461 gatgtcactt ctgaggtcca gggtctgtgg aggcgcctga acacactgca gcattacaag
5521 gtcccagatg gagcaactgt ggccctcgtc ccctgcctca ccaagcatgt gctccgggaa
5581 aaccaggatt atgtccctgg agagcggacc ccaatgctgg aggatgtaga tgaggggggc
5641 atccggccct ggcacctggt gaagccaagt gatgagccgg agccgcccag gcctcggagg
5701 ggcagccttc ggggcgggga gcgtgagcgc gccaaggcca tccctgagat ctacctgacc
5761 cgcctgctgt ccatgaaggg caccctgcag aagttcgtgg atgacctgtt ccaggtgatt
5821 ctcagcacca gccgccccgt gccgctcgct gtgaagtact tctttgacct gctggatgag
5881 caggcccagc agcatggcat ctccgaccag gacaccatcc acatctggaa gaccaacagc
5941 ttgcctctga ggttctggat caatataata aaaaacccgc agtttgtgtt cgacgtgcaa
6001 acatctgata acatggatgc ggtgctcctt gtcattgcac agaccttcat ggacgcctgc
6061 accctggccg accacaagct gggccgggac tccccgatca acaaacttct gtatgcacgg
6121 gacattcccc ggtacaagcg gatggtggaa aggtactatg cagacatcag acagactgtc
6181 ccagccagcg accaagagat gaactctgtc ctggctgaac tgtcctggaa ctactccgga
6241 gacctcgggg cgcgagtggc cctgcatgaa ctctacaagt acatcaacaa gtactatgac
6301 cagatcatca ctgccctgga ggaggatggc acggcccaga agatgcagct gggctatcgg
6361 ctccagcaga ttgcagctgc tgtggaaaac aaggtcacag atctatagga acccaggagc
6421 cacggcctgc tgttgcttca gcctggcctg ggcagccctg gaagctcgga ggagaggcca
6481 ccttcttagg tgcctgtagt gactgacaag cagagttagt ggaaggtgac tcccagtctc
6541 ctggtggctc tggcctcggc cctgctggat ccacctccta gacccggggc ctcaaggctc
6601 atggggtagt acccagcctg ctccccgagt ccagcgaccc tgt
//