LOCUS X87342 3480 bp mRNA linear HUM 30-MAY-1995
DEFINITION H.sapiens mRNA for human giant larvae homolog.
ACCESSION X87342
VERSION X87342.1
KEYWORDS HGL; Human giant larvae homolog.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Wiemann S., Tommerup N., Celis J.E., Ansorge W., Leffers H.
TITLE A human homolog of the Drosophila 1(2) giant larvae tumor
suppressor maps to 17q24-25
JOURNAL Unpublished.
REFERENCE 2 (bases 1 to 3480)
AUTHORS Leffers H.
JOURNAL Submitted (22-MAY-1995) to the INSDC. H. Leffers, National
University Hospital, Dept of Growth & Reproduction, Blegdamsvej 9,
DK-2100 Copenhagen, DENMARK
FEATURES Location/Qualifiers
source 1..3480
/db_xref="H-InvDB:HIT000324279"
/organism="Homo sapiens"
/chromosome="17"
/map="q24-25"
/mol_type="mRNA"
/clone_lib="lambda ZAP II, cDNA"
/clone="HGL"
/cell_line="transformed amnion cells (AMA)"
/db_xref="taxon:9606"
CDS 131..3178
/gene="HGL"
/product="Human giant larvae homologue"
/db_xref="GOA:Q6P1M3"
/db_xref="H-InvDB:HIT000324279.12"
/db_xref="HGNC:HGNC:6629"
/db_xref="InterPro:IPR000664"
/db_xref="InterPro:IPR001680"
/db_xref="InterPro:IPR013577"
/db_xref="InterPro:IPR015943"
/db_xref="InterPro:IPR019775"
/db_xref="InterPro:IPR036322"
/db_xref="PDB:3WP0"
/db_xref="PDB:3WP1"
/db_xref="PDB:6N8P"
/db_xref="PDB:6N8Q"
/db_xref="PDB:6N8R"
/db_xref="PDB:6N8S"
/db_xref="UniProtKB/Swiss-Prot:Q6P1M3"
/protein_id="CAA60780.1"
/translation="MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSL
HILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSL
KVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPA
FRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDL
QGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYG
PFPCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIG
FTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHH
VSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFW
DASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQ
KIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAA
RSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFV
KCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAK
AERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGG
TIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHD
LSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRA
EDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLIS
PSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQP
GLVMERALLSDERAATGVHIEPPWGAASAMAEQSEWLSVQAAR"
regulatory 3459..3464
/regulatory_class="polyA_signal_sequence"
BASE COUNT 623 a 1128 c 1103 g 626 t
ORIGIN
1 cgcccagcag cccgtgggca ggcgcggcgg agcgagcggg gccggcggcg ggcgccgagg
61 gacgccgagg cctcgggcgg gggctggccc ggggttccag gtctccagtg ggggctgcag
121 actaagcaaa atgaggcggt tcctgaggcc agggcatgac cctgtgcggg agaggctcaa
181 gcgggacctg ttccagttta acaagacggt ggagcatggc ttcccgcacc agcccagcgc
241 cctcggctac agcccgtccc tgcacatcct ggccatcggc acccgttctg gagccatcaa
301 gctctacgga gccccaggcg tggagttcat ggggctgcac caggagaaca acgctgtgac
361 gcagatccac ctcctgcccg gccagtgcca gctggtcacc ctgctggatg acaacagcct
421 gcacctttgg agcctgaagg tcaagggcgg ggcatcggag ctgcaggagg atgagagctt
481 cacactgcgt ggacccccag gggctgcccc cagtgccaca cagatcaccg tggtcctgcc
541 acattcctcc tgcgagctgc tctacctggg caccgagagt ggcaacgtgt ttgtggtgca
601 gctgccagct tttcgtgcgc tggaggaccg gaccatcagc tcggacgcgg tgctgcagcg
661 gttgccagag gaggcccgcc accggcgtgt gttcgagatg gtggaggcac tgcaggagca
721 ccctcgagac cccaaccaga tcctgatcgg ctacagccga ggcctcgttg tcatctggga
781 cctacagggc agccgcgtgc tctaccactt cctcagcagc cagcaactgg agaacatctg
841 gtggcagcgg gacggccgcc tgctcgtcag ctgtcactct gacggcagct actgccagtg
901 gcccgtgtcc agcgaagccc agcaaccaga gcccctccgc agcctcgtgc cttacggtcc
961 ctttccttgc aaagcgatta ccagaatcct ctggctgacc actaggcagg ggttgccctt
1021 caccatcttc cagggtggca tgccacgggc cagctacggg gaccgccact gcatctcagt
1081 gatccacgat ggccagcaga cggccttcga cttcacctcc cgtgtcatcg gcttcactgt
1141 cctcacagag gcagaccctg cagccacctt tgacgacccc tatgccctgg tggtgctggc
1201 tgaggaggag ctggtggtga ttgacctgca gacagcaggc tggccaccgg tccagctgcc
1261 ctacctggct tctctgcact gttccgccat cacctgctct caccacgtct ccaacatccc
1321 gctgaagctg tgggagcgga tcattgccgc cggcagccgg cagaacgcac acttctccac
1381 catggagtgg ccaattgatg gtggcaccag cctgacccca gccccacccc agagggacct
1441 gctgctcaca gggcacgagg acggcacggt gcggttctgg gatgcctcgg gtgtctgcct
1501 gcggctgctc tacaaactca gcactgtgcg cgtgttcctc accgacacgg accccaacga
1561 gaacttcagt gcccagggcg aggacgagtg gcccccactc cgcaaggtgg gctcctttga
1621 cccctacagt gatgaccccc ggctgggcat ccagaagatc ttcctctgca agtacagcgg
1681 ctacctggct gtggcaggca cggcagggca ggtgctggta ctggaactga atgacgaggc
1741 agcggagcag gctgtggagc aggtggaggc cgacctgctg caggaccaag agggctaccg
1801 ctggaagggg cacgagcgcc tggcagcccg ctcagggccc gtgcgctttg agcctggctt
1861 tcagcccttc gtgttggtgc agtgtcagcc cccggctgtg gtcacctcct tggccctgca
1921 ctctgagtgg cggctcgtgg ccttcggcac cagccatggc tttggcctct ttgaccacca
1981 gcagcggcgg caggtctttg ttaagtgcac actgcacccc agtgaccagc tggccttgga
2041 gggcccactc tcccgcgtca agtccctcaa gaagtccttg cgtcagtcat tccgccggat
2101 gcgtcggagc cgggtgtcca gccggaagcg gcacccggct ggccccccag gagaggcaca
2161 ggaggggagt gccaaggctg agcggccagg cctccagaac atggagctgg cgcctgtgca
2221 gcgcaagatc gaggctcgct cggcagagga ctccttcaca ggcttcgtcc ggaccctgta
2281 ctttgctgac acctacctga aggacagctc ccggcactgc ccctcgctgt gggctggcac
2341 caatgggggc accatctatg ccttctccct gcgtgtgcct cccgccgagc ggagaatgga
2401 tgagcctgtg cgggcagagc aggccaagga gatccagctg atgcaccggg cgccggtggt
2461 gggcatcctg gtgctcgacg gacacagcgt accccttccc gagcccctcg aagtggccca
2521 tgatctgtcg aagagccctg acatgcaggg aagccaccag ctgctcgtcg tatcagagga
2581 gcagttcaag gtgttcacgc tgcccaaggt gagtgccaag ctgaagttga agctgacggc
2641 cctggagggc tcaagagtgc ggcgggtcag cgtggcccac ttcggcagtc gtcgagccga
2701 ggactacggg gagcaccacc tggcagtcct taccaacctg ggcgacatcc aggtggtctc
2761 gctgcccctg ctcaagcccc aggtgcgcta cagctgcatc cgccgggagg acgtcagtgg
2821 catcgcctcc tgcgtcttca ccaaatatgg ccaaggcttc tacctgatct caccctcgga
2881 gtttgagcgc ttctctctct ccaccaagtg gctggtggag ccccggtgtc tggtggattc
2941 agcagaaacc aagaaccacc gccctggtaa cggtgcgggc cccaagaagg ccccgagccg
3001 agccaggaac tcagggactc agagtgatgg cgaggagaag cagcccggcc tggtgatgga
3061 gcgcgctctg ctcagtgatg agagagcggc aactggcgtt cacatcgagc cgccgtgggg
3121 tgcagcctca gcaatggcgg agcagagtga gtggctgagc gtccaggctg cgcgatgagc
3181 acacactact actgatggcc tttcgggggt ccctgcccca accggagagg ccggtgcaca
3241 gggccccgcc aggggctggg ggcatcccgg cttccacaat gcagctgctc tgggcctcgg
3301 gagaggagag accccagtcc cctgggctgc ccttcccggg cctcgtctgt ctgggtcctt
3361 tggtcaatgt tgcacagttt ttattgctcc catccctttt tgtagtgggc tgggttttaa
3421 gttataaatg ttaactgcct ctgggtgaaa aagtttttaa taaacaccta ttacctcttg
//