LOCUS X87176 2593 bp mRNA linear HUM 09-SEP-2004
DEFINITION H.sapiens mRNA for 17-beta-hydroxysteroid dehydrogenase.
ACCESSION X87176
VERSION X87176.1
KEYWORDS 17-beta-hydroxysteroid dehydrogenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 2 (bases 1 to 2593)
AUTHORS De Launoit Y.P.
JOURNAL Submitted (11-MAY-1995) to the INSDC. Y.P. de Launoit, CNRS URA
1160 - Unite d Oncologie Mol., Institut Pasteur de Lille, 1 rue
Calmette, F- 59019 - Lille Cedex, FRANCE
REFERENCE 3 (bases 1 to 2593)
AUTHORS Adamski J., Normand T., Leenders F., Monte D., Begue A.,
Stehelin D., Jungblut P.W., de Launoit Y.
TITLE Molecular cloning of a novel widely expressed human 80 kDa
17beta-hydroxysteroid dehydrogenase IV
JOURNAL Biochem. J. 311, 437-443(1995).
PUBMED 7487879
FEATURES Location/Qualifiers
source 1..2593
/db_xref="H-InvDB:HIT000324265"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_type="liver"
/db_xref="taxon:9606"
CDS 49..2259
/product="17beta-hydroxysteroid dehydrogenase"
/db_xref="GOA:P51659"
/db_xref="H-InvDB:HIT000324265.13"
/db_xref="HGNC:HGNC:5213"
/db_xref="InterPro:IPR002347"
/db_xref="InterPro:IPR002539"
/db_xref="InterPro:IPR003033"
/db_xref="InterPro:IPR020904"
/db_xref="InterPro:IPR029069"
/db_xref="InterPro:IPR036291"
/db_xref="InterPro:IPR036527"
/db_xref="InterPro:IPR039569"
/db_xref="PDB:1IKT"
/db_xref="PDB:1S9C"
/db_xref="PDB:1ZBQ"
/db_xref="UniProtKB/Swiss-Prot:P51659"
/protein_id="CAA60643.1"
/translation="MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGD
FKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGI
LRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFG
QANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYV
APLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKI
CDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPP
FSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLA
EIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSE
KELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLS
GDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKP
VYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQS
TFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKG
AADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL"
BASE COUNT 757 a 471 c 643 g 722 t
ORIGIN
1 ggccagcgcg tctgcttgtt cgtgtgtgtg tcgttgcagg ccttattcat gggctcaccg
61 ctgaggttcg acgggcgggt ggtactggtc accggcgcgg gggcaggatt gggccgagcc
121 tatgccctgg cttttgcaga aagaggagcg ttagttgttg tgaatgattt gggaggggac
181 ttcaaaggag ttggtaaagg ctccttagct gctgataagg ttgttgaaga aataagaagg
241 agaggtggaa aagcagtggc caactatgat tcagtggaag aaggagagaa ggttgtgaag
301 acagccctgg atgcttttgg aagaatagat gttgtggtca acaatgctgg aattctgagg
361 gatcgttcct ttgctaggat aagtgatgaa gactgggata taatccacag agttcatttg
421 cggggttcat tccaagtgac acgggcagca tgggaacaca tgaagaaaca gaagtatgga
481 aggattatta tgacttcatc agcttcagga atatatggca actttggcca ggccaattat
541 agtgctgcaa agttgggtct tctgggcctt gcaaattctc ttgcaattga aggcaggaaa
601 agcaacattc attgtaacac cattgctcct aatgcgggat cacggatgac tcagacagtt
661 atgcctgaag atcttgtgga agccctgaag ccagagtatg tggcacctct tgtcctttgg
721 ctttgtcacg agagttgtga ggagaatggt ggcttgtttg aggttggagc aggatggatt
781 ggaaaattac gctgggagcg gactcttgga gctattgtaa gacaaaagaa tcacccaatg
841 actcctgagg cagtcaaggc taactggaag aagatctgtg actttgagaa tgccagcaag
901 cctcagagta tccaagaatc aactggcagt ataattgaag ttctgagtaa aatagattca
961 gaaggaggag tttcagcaaa tcatactagt cgtgcaacgt ctacagcaac atcaggattt
1021 gctggagcta ttggccagaa actccctcca ttttcttatg cttatacgga actggaagct
1081 attatgtatg cccttggagt gggagcgtca atcaaggatc caaaagattt gaaatttatt
1141 tatgaaggaa gttctgattt ctcctgtttg cccaccttcg gagttatcat aggtcagaaa
1201 tctatgatgg gtggaggatt agcagaaatt cctggacttt caatcaactt tgcaaaggtt
1261 cttcatggag agcagtactt agagttatat aaaccacttc ccagagcagg aaaattaaaa
1321 tgtgaagcag ttgttgctga tgtcctagat aaaggatccg gtgtagtgat tattatggat
1381 gtctattctt attctgagaa ggaacttata tgccacaatc agttctctct ctttcttgtt
1441 ggctctggag gctttggtgg aaaacggaca tcagacaaag tcaaggtagc tgtagccata
1501 cctaatagac ctcctgatgc tgtacttaca gataccacct ctcttaatca ggctgctttg
1561 taccgcctca gtggagactg gaatccctta cacattgatc ctaactttgc tagtctagca
1621 ggttttgaca agcccatatt acatggatta tgtacatttg gattttctgc caggcgtgtg
1681 ttacagcagt ttgcagataa tgatgtgtca agattcaagg caattaaggc tcgttttgca
1741 aaaccagtat atccaggaca aactctacaa actgagatgt ggaaggaagg aaacagaatt
1801 cattttcaaa ccaaggtcca agaaactgga gacattgtca tttcaaatgc atatgtggat
1861 cttgcaccaa catctggtac ttcagctaag acaccctctg agggcgggaa gcttcagagt
1921 acctttgtat ttgaggaaat aggacgccgc ctaaaggata ttgggcctga ggtggtgaag
1981 aaagtaaatg ctgtatttga gtggcatata accaaaggcg gaaatattgg ggctaagtgg
2041 actattgacc tgaaaagtgg ttctggaaaa gtgtaccaag gccctgcaaa aggtgctgct
2101 gatacaacaa tcatactttc agatgaagat ttcatggagg tggtcctggg caagcttgac
2161 cctcagaagg cattctttag tggcaggctg aaggccagag ggaacatcat gctgagccag
2221 aaacttcaga tgattcttaa agactacgcc aagctctgaa gggcacacta cactattaat
2281 aaaaatggaa tcattaaata ctctcttcac ccaaatatgc ttgattattc tgcaaaagtg
2341 attagaacta agatgcaggg gaaattgctt aacattttca gatatcagat aactgcagat
2401 tttcattttc tactaatttt catgtatcat tatttttaca aggaactata tataagctag
2461 cacatgatta tccttctgtt cttagatctg tatcttcata ataaaaaatt ttgcccaagt
2521 cctgtttcct tagaatttgt gatagcattg ataagttgaa aggaaaatta aatcaataaa
2581 ggcctttgat acc
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